REACTION: R10309
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Entry
R10309 Reaction
Name
(1'S)-averantin:NADP+ oxidoreductase
Definition
(1'S)-Averantin + NADP+ <=> Norsolorinic acid + NADPH + H+
Equation
C20499
+
C00006
<=>
C20452
+
C00005
+
C00080
Reaction class
RC00001
C00005_C00006
RC01491
C20452_C20499
Enzyme
1.1.1.349
Pathway
rn00254
Aflatoxin biosynthesis
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Module
M00937
Aflatoxin biosynthesis, malonyl-CoA => aflatoxin B1
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.349
R10309 (1'S)-Averantin + NADP+ <=> Norsolorinic acid + NADPH + H+
BRITE hierarchy
Orthology
K17644
norsolorinic acid ketoreductase [EC:
1.1.1.349
]
Other DBs
RHEA:
35450
LinkDB
All DBs
RCLASS: RC01491
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Entry
RC01491 RClass
Definition
C1c-C5a:*-*:C1b+C8y+O1a-C1b+C8y+O5a
Reactant pair
C07475_C10157
C11829_C11830
C16453_C19574
C20452_C20499
Related class
DB search
Reaction
R06266
R06269
R08424
R09420
R10309
Enzyme
1.1.1.146
1.1.1.184
1.1.1.349
1.3.1.20
1.14.13.81
1.21.98.3
Pathway
rn00254
Aflatoxin biosynthesis
rn00860
Porphyrin metabolism
rn00960
Tropane, piperidine and pyridine alkaloid biosynthesis
rn00980
Metabolism of xenobiotics by cytochrome P450
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Orthology
K00079
carbonyl reductase 1 [EC:
1.1.1.184
1.1.1.189
1.1.1.197
]
K00081
carbonyl reductase 2 [EC:
1.1.1.184
]
K00084
carbonyl reductase 3 [EC:
1.1.1.184
]
K00212
20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:
1.1.1.149
1.1.1.357
1.3.1.20
]
K04034
anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase [EC:
1.21.98.3
]
K04035
magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase [EC:
1.14.13.81
]
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
K17644
norsolorinic acid ketoreductase [EC:
1.1.1.349
]
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