REACTION: R13040
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Entry
R13040 Reaction
Definition
5(S)-HETE + NADP+ <=> 5-OxoETE + NADPH + H+
Equation
C04805
+
C00006
<=>
C14732
+
C00005
+
C00080
Comment
5-hydroxyeicosanoid dehydrogenase
Reaction class
RC00241
C04805_C14732
Enzyme
1.1.1.-
Pathway
rn00590
Arachidonic acid metabolism
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.-
R13040 5(S)-HETE + NADP+ <=> 5-OxoETE + NADPH + H+
BRITE hierarchy
Reference
1 [PMID:
24056189
]
Authors
Powell WS, Rokach J.
Title
The eosinophil chemoattractant 5-oxo-ETE and the OXE receptor.
Journal
Prog Lipid Res 52:651-65 (2013)
DOI:
10.1016/j.plipres.2013.09.001
LinkDB
All DBs
RCLASS: RC00241
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Entry
RC00241 RClass
Definition
C1c-C5a:*-*:C1b+C2b+O1a-C1b+C2b+O5a
Reactant pair
C00584_C04707
C00639_C05960
C00696_C04758
C01312_C04835
C02165_C05949
C04577_C04742
C04654_C04741
C04805_C14732
C14762_C14765
C16469_C16471
C20943_C20944
Related class
DB search
Reaction
R02580
R02683
R02800
R03520
R03863
R03864
R04517
R04518
R04552
R07058
R08094
R10918
R10919
R13040
Enzyme
1.1.1.35
1.1.1.141
1.1.1.196
1.1.1.197
1.1.1.231
1.1.1.232
1.1.1.386
1.1.1.-
1.3.1.48
Pathway
rn00590
Arachidonic acid metabolism
rn00591
Linoleic acid metabolism
rn00902
Monoterpenoid biosynthesis
rn00907
Pinene, camphor and geraniol degradation
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01120
Microbial metabolism in diverse environments
Orthology
K00022
3-hydroxyacyl-CoA dehydrogenase [EC:
1.1.1.35
]
K00069
15-hydroxyprostaglandin dehydrogenase (NAD) [EC:
1.1.1.141
]
K01782
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:
1.1.1.35
4.2.1.17
5.1.2.3
]
K01825
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:
1.1.1.35
4.2.1.17
5.1.2.3
5.3.3.8
]
K07119
prostaglandin reductase 3 [EC:
1.3.1.48
]
K13948
prostaglandin reductase 1 [EC:
1.3.1.74
1.3.1.48
]
K13949
prostaglandin reductase 2 [EC:
1.3.1.48
]
K20142
ipsdienol dehydrogenase [EC:
1.1.1.386
]
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integrated database retrieval system
