KEGG   PATHWAY: acc00290
Entry
acc00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Acinetobacter pittii
Class
Metabolism; Amino acid metabolism
Pathway map
acc00290  Valine, leucine and isoleucine biosynthesis
acc00290

Module
acc_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:acc00290]
acc_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:acc00290]
acc_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:acc00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Acinetobacter pittii [GN:acc]
Gene
BDGL_001397  ilvA; threonine dehydratase biosynthetic (threonine deaminase) [KO:K01754] [EC:4.3.1.19]
BDGL_002245  tdcB; threonine dehydratase catabolic [KO:K01754] [EC:4.3.1.19]
BDGL_003327  leuC; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
BDGL_003328  leuD; 3-isopropylmalate isomerase subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
BDGL_003330  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
BDGL_003453  ilvI; acetolactate synthase III, large subunit [KO:K01652] [EC:2.2.1.6]
BDGL_000235  hypothetical protein [KO:K01652] [EC:2.2.1.6]
BDGL_003454  ilvH; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
BDGL_003455  ilvC; ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
BDGL_002927  ilvD1; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
BDGL_002369  ilvE; branched-chain amino acid transferase [KO:K00826] [EC:2.6.1.42]
BDGL_000849  putative PLP-dependent aminotransferase [KO:K14260] [EC:2.6.1.66 2.6.1.2]
BDGL_003385  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
acc00260  Glycine, serine and threonine metabolism
acc00280  Valine, leucine and isoleucine degradation
acc00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

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