KEGG   PATHWAY: amg00280
Entry
amg00280                    Pathway                                
Name
Valine, leucine and isoleucine degradation - Alteromonas macleodii English Channel 673
Class
Metabolism; Amino acid metabolism
Pathway map
amg00280  Valine, leucine and isoleucine degradation
amg00280

Module
amg_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:amg00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Alteromonas macleodii English Channel 673 [GN:amg]
Gene
AMEC673_01430  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
AMEC673_05245  leucine dehydrogenase [KO:K00263] [EC:1.4.1.9]
AMEC673_09775  alpha keto acid dehydrogenase complex, E1 component subunit alpha [KO:K00166] [EC:1.2.4.4]
AMEC673_09780  2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type subunit beta [KO:K00167] [EC:1.2.4.4]
AMEC673_09785  dihydrolipoamide acetyltransferase [KO:K09699] [EC:2.3.1.168]
AMEC673_14340  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
AMEC673_11065  acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
AMEC673_00465  Acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
AMEC673_07685  isovaleryl-CoA dehydrogenase [KO:K00253] [EC:1.3.8.4]
AMEC673_02395  fadB; multifunctional fatty acid oxidation complex subunit alpha [KO:K01825] [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
AMEC673_05875  fadJ; multifunctional fatty acid oxidation complex subunit alpha [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
AMEC673_05870  fadI; 3-ketoacyl-CoA thiolase [KO:K00632] [EC:2.3.1.16]
AMEC673_02390  fadA; 3-ketoacyl-CoA thiolase [KO:K00632] [EC:2.3.1.16]
AMEC673_15890  3-hydroxyisobutyrate dehydrogenase [KO:K00020] [EC:1.1.1.31]
AMEC673_15885  methylmalonate-semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.18 1.2.1.27]
AMEC673_16405  methylmalonate-semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.18 1.2.1.27]
AMEC673_02200  NAD-dependent aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
AMEC673_07670  methylcrotonyl-CoA carboxylase subunit alpha [KO:K01968] [EC:6.4.1.4]
AMEC673_07680  methylcrotonyl CoA carboxylase subunit beta [KO:K01969] [EC:6.4.1.4]
AMEC673_07675  Enoyl-CoA hydratase/isomerase [KO:K13766] [EC:4.2.1.18]
AMEC673_07665  hydroxymethylglutaryl-CoA lyase [KO:K01640] [EC:4.1.3.4]
AMEC673_09720  putative succinyl-CoA transferase subunit alpha [KO:K01028] [EC:2.8.3.5]
AMEC673_09715  3-oxoacid CoA-transferase subunit B family enzyme [KO:K01029] [EC:2.8.3.5]
AMEC673_08090  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AMEC673_07695  acetyl-CoA acetyltransferase with thiolase domain [KO:K00626] [EC:2.3.1.9]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
amg00020  Citrate cycle (TCA cycle)
amg00240  Pyrimidine metabolism
amg00290  Valine, leucine and isoleucine biosynthesis
amg00640  Propanoate metabolism
amg00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   
LinkDB

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