KEGG   PATHWAY: ath00350
Entry
ath00350                    Pathway                                
Name
Tyrosine metabolism - Arabidopsis thaliana (thale cress)
Class
Metabolism; Amino acid metabolism
Pathway map
ath00350  Tyrosine metabolism
ath00350

Module
ath_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:ath00350]
Other DBs
GO: 0006570
Organism
Arabidopsis thaliana (thale cress) [GN:ath]
Gene
AT1G06570  PDS1; 4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
AT1G12050  [KO:K01555] [EC:3.7.1.2]
AT1G22430  [KO:K00121] [EC:1.1.1.284 1.1.1.1]
AT1G22440  [KO:K00121] [EC:1.1.1.284 1.1.1.1]
AT1G31670  [KO:K00276] [EC:1.4.3.21]
AT1G31690  [KO:K00276] [EC:1.4.3.21]
AT1G31710  [KO:K00276] [EC:1.4.3.21]
AT1G32780  [KO:K00001] [EC:1.1.1.1]
AT1G62800  ASP4; aspartate aminotransferase 4 [KO:K14454] [EC:2.6.1.1]
AT1G62810  CuAO1; Copper amine oxidase family protein [KO:K00276] [EC:1.4.3.21]
AT1G64710  [KO:K00001] [EC:1.1.1.1]
AT1G71920  HISN6B; HISTIDINE BIOSYNTHESIS 6B [KO:K00817] [EC:2.6.1.9]
AT1G77120  ADH1; alcohol dehydrogenase 1 [KO:K18857] [EC:1.1.1.1]
AT2G02380  GSTZ2; glutathione S-transferase (class zeta) 2 [KO:K01800] [EC:5.2.1.2]
AT2G02390  GSTZ1; glutathione S-transferase zeta 1 [KO:K01800] [EC:5.2.1.2]
AT2G20340  AAS; Pyridoxal phosphate (PLP)-dependent transferases superfamily protein [KO:K01593] [EC:4.1.1.28 4.1.1.105]
AT2G22250  AAT; aspartate aminotransferase [KO:K15849] [EC:2.6.1.1 2.6.1.78 2.6.1.79]
AT2G24850  TAT3; tyrosine aminotransferase 3 [KO:K00815] [EC:2.6.1.5]
AT2G30970  ASP1; aspartate aminotransferase 1 [KO:K14455] [EC:2.6.1.1]
AT2G42490  [KO:K00276] [EC:1.4.3.21]
AT3G16700  [KO:K01557] [EC:3.7.1.5]
AT3G43670  [KO:K00276] [EC:1.4.3.21]
AT4G12290  [KO:K00276] [EC:1.4.3.21]
AT4G14940  AO1; amine oxidase 1 [KO:K00276] [EC:1.4.3.21]
AT4G15940  [KO:K01557] [EC:3.7.1.5]
AT4G22110  [KO:K00121] [EC:1.1.1.284 1.1.1.1]
AT4G23590  [KO:K00815] [EC:2.6.1.5]
AT4G28410  [KO:K00815] [EC:2.6.1.5]
AT4G28420  [KO:K00815] [EC:2.6.1.5]
AT4G28680  TYRDC; L-tyrosine decarboxylase [KO:K01592] [EC:4.1.1.25]
AT4G31990  ASP5; aspartate aminotransferase 5 [KO:K00811] [EC:2.6.1.1]
AT5G10330  HPA1; histidinol phosphate aminotransferase 1 [KO:K00817] [EC:2.6.1.9]
AT5G11520  ASP3; aspartate aminotransferase 3 [KO:K14454] [EC:2.6.1.1]
AT5G19550  ASP2; aspartate aminotransferase 2 [KO:K14454] [EC:2.6.1.1]
AT5G24760  [KO:K00001] [EC:1.1.1.1]
AT5G36160  [KO:K00815] [EC:2.6.1.5]
AT5G42250  [KO:K00121] [EC:1.1.1.284 1.1.1.1]
AT5G43940  HOT5; GroES-like zinc-binding dehydrogenase family protein [KO:K00121] [EC:1.1.1.284 1.1.1.1]
AT5G53970  TAT7; Tyrosine transaminase family protein [KO:K00815] [EC:2.6.1.5]
AT5G54080  HGO; homogentisate 1,2-dioxygenase [KO:K00451] [EC:1.13.11.5]
AT5G57170  [KO:K07253] [EC:5.3.2.1]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
ath00020  Citrate cycle (TCA cycle)
ath00360  Phenylalanine metabolism
ath00400  Phenylalanine, tyrosine and tryptophan biosynthesis
ath00620  Pyruvate metabolism
ath00650  Butanoate metabolism
ath00940  Phenylpropanoid biosynthesis
ath00950  Isoquinoline alkaloid biosynthesis
KO pathway
ko00350   

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