KEGG   PATHWAY: ats00061
Entry
ats00061                    Pathway                                
Name
Fatty acid biosynthesis - Aegilops tauschii (wheat D)
Class
Metabolism; Lipid metabolism
Pathway map
ats00061  Fatty acid biosynthesis
ats00061

Module
ats_M00082  Fatty acid biosynthesis, initiation [PATH:ats00061]
ats_M00083  Fatty acid biosynthesis, elongation [PATH:ats00061]
ats_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:ats00061]
Other DBs
GO: 0006633
Organism
Aegilops tauschii (wheat D) [GN:ats]
Gene
109753542  acetyl-CoA carboxylase 1 [KO:K11262] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
109754335  acetyl-CoA carboxylase 2-like [KO:K11262] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
109753580  malonate--CoA ligase [KO:K18660] [EC:6.2.1.76 6.2.1.-]
109785446  uncharacterized protein LOC109785446 [KO:K00645] [EC:2.3.1.39]
109782252  3-oxoacyl-[acyl-carrier-protein] synthase III, chloroplastic [KO:K00648] [EC:2.3.1.180]
109747300  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
109752735  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
109741331  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109782457  3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial isoform X1 [KO:K09458] [EC:2.3.1.179]
109758063  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109733888  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109772431  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109777613  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109779150  3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic-like isoform X1 [KO:K00059] [EC:1.1.1.100]
109741677  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109741688  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109783977  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109782171  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109743774  3-oxoacyl-[acyl-carrier-protein] reductase 4-like [KO:K00059] [EC:1.1.1.100]
109753388  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109755486  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109758636  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109773627  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109768910  uncharacterized protein LOC109768910 [KO:K00059] [EC:1.1.1.100]
109746058  uncharacterized protein LOC109746058 [KO:K02372] [EC:4.2.1.59]
109775828  enoyl-[acyl-carrier-protein] reductase [NADH] 2, chloroplastic [KO:K00208] [EC:1.3.1.9 1.3.1.10]
109748461  enoyl-[acyl-carrier-protein] reductase [NADH] 1, chloroplastic [KO:K00208] [EC:1.3.1.9 1.3.1.10]
109763440  probable trans-2-enoyl-CoA reductase, mitochondrial [KO:K07512] [EC:1.3.1.- 1.3.1.38]
109747972  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
109761208  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
109765270  oleoyl-acyl carrier protein thioesterase 1, chloroplastic-like [KO:K10782] [EC:3.1.2.14]
109737747  stearoyl-[acyl-carrier-protein] 9-desaturase 5, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109779328  acyl-[acyl-carrier-protein] desaturase 4, chloroplastic-like isoform X1 [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109743731  stearoyl-[acyl-carrier-protein] 9-desaturase 5, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109782689  acyl-[acyl-carrier-protein] desaturase 7, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109747362  stearoyl-[acyl-carrier-protein] 9-desaturase 1, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109748975  acyl-[acyl-carrier-protein] desaturase 7, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109759486  acyl-[acyl-carrier-protein] desaturase 7, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109766563  stearoyl-[acyl-carrier-protein] 9-desaturase 5, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109742804  stearoyl-[acyl-carrier-protein] 9-desaturase 2, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109748642  stearoyl-[acyl-carrier-protein] 9-desaturase 5, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109749248  acyl-[acyl-carrier-protein] desaturase 7, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109763251  acyl-[acyl-carrier-protein] desaturase 4, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109763252  acyl-[acyl-carrier-protein] desaturase 4, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109739555  long chain acyl-CoA synthetase 9, chloroplastic-like [KO:K01897] [EC:6.2.1.3]
109753022  long chain acyl-CoA synthetase 2 [KO:K01897] [EC:6.2.1.3]
109760892  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
109736138  probable acyl-activating enzyme 16, chloroplastic [KO:K01897] [EC:6.2.1.3]
109736139  probable acyl-activating enzyme 16, chloroplastic [KO:K01897] [EC:6.2.1.3]
109779749  long chain acyl-CoA synthetase 6, peroxisomal-like isoform X1 [KO:K01897] [EC:6.2.1.3]
109779770  long chain acyl-CoA synthetase 8 [KO:K01897] [EC:6.2.1.3]
109759520  long chain acyl-CoA synthetase 9, chloroplastic-like [KO:K01897] [EC:6.2.1.3]
109763519  long chain acyl-CoA synthetase 4-like isoform X1 [KO:K01897] [EC:6.2.1.3]
109772725  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
109741381  long chain acyl-CoA synthetase 6, peroxisomal-like isoform X1 [KO:K01897] [EC:6.2.1.3]
109774792  long chain acyl-CoA synthetase 1 [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
ats00020  Citrate cycle (TCA cycle)
ats00062  Fatty acid elongation
ats00071  Fatty acid degradation
ats00410  beta-Alanine metabolism
ats00561  Glycerolipid metabolism
ats00564  Glycerophospholipid metabolism
ats00620  Pyruvate metabolism
ats00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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