KEGG   PATHWAY: bhz00290
Entry
bhz00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Bordetella hinzii
Class
Metabolism; Amino acid metabolism
Pathway map
bhz00290  Valine, leucine and isoleucine biosynthesis
bhz00290

Module
bhz_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:bhz00290]
bhz_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bhz00290]
bhz_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:bhz00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Bordetella hinzii [GN:bhz]
Gene
ACR54_01095  tdcB_1; L-threonine dehydratase catabolic TdcB [KO:K01754] [EC:4.3.1.19]
ACR54_04238  ilvA; L-threonine dehydratase biosynthetic IlvA [KO:K01754] [EC:4.3.1.19]
ACR54_01805  leuC_2; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
ACR54_00184  leuC_1; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
ACR54_02459  leuC_3; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
ACR54_01806  leuD1; 3-isopropylmalate dehydratase small subunit 1 [KO:K01704] [EC:4.2.1.33 4.2.1.35]
ACR54_00185  leuD_1; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
ACR54_02460  leuD_2; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
ACR54_01807  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
ACR54_01082  ilvI_1; Acetolactate synthase isozyme 3 large subunit [KO:K01652] [EC:2.2.1.6]
ACR54_01554  ilvX; Putative acetolactate synthase large subunit IlvX [KO:K01652] [EC:2.2.1.6]
ACR54_01557  ilvG_1; Acetolactate synthase isozyme 2 large subunit [KO:K01652] [EC:2.2.1.6]
ACR54_00851  ilvB; Acetolactate synthase large subunit [KO:K01652] [EC:2.2.1.6]
ACR54_02296  ilvG_2; Acetolactate synthase isozyme 2 large subunit [KO:K01652] [EC:2.2.1.6]
ACR54_02522  ilvG_3; Acetolactate synthase isozyme 2 large subunit [KO:K01652] [EC:2.2.1.6]
ACR54_04581  ilvI_2; Acetolactate synthase isozyme 3 large subunit [KO:K01652] [EC:2.2.1.6]
ACR54_01083  ilvH; Acetolactate synthase isozyme 3 small subunit [KO:K01653] [EC:2.2.1.6]
ACR54_01084  ilvC; Ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
ACR54_00380  ilvD_1; Dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
ACR54_02415  ilvD_2; Dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
ACR54_00505  ilvE_1; Branched-chain-amino-acid aminotransferase [KO:K00826] [EC:2.6.1.42]
ACR54_03651  ilvE_3; Branched-chain-amino-acid aminotransferase [KO:K00826] [EC:2.6.1.42]
ACR54_03335  ilvE_2; Branched-chain-amino-acid aminotransferase [KO:K00826] [EC:2.6.1.42]
ACR54_03865  leuA_1; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
ACR54_04537  leuA_2; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
bhz00260  Glycine, serine and threonine metabolism
bhz00280  Valine, leucine and isoleucine degradation
bhz00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

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