KEGG   PATHWAY: cgib00533
Entry
cgib00533                   Pathway                                
Name
Glycosaminoglycan biosynthesis - keratan sulfate - Carassius gibelio (silver crucian carp)
Description
Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, Gal(b1-4)GlcNAc(b1-3), with sulfate esters at C-6 of GlcNAc and Gal residues. There are two types of KS distinguished by the protein linkage: type I for N-linked via the N-glycan core structure and type II for O-linked via the O-glycan core 2 structure.
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
cgib00533  Glycosaminoglycan biosynthesis - keratan sulfate
cgib00533

Other DBs
GO: 0018146
Organism
Carassius gibelio (silver crucian carp) [GN:cgib]
Gene
127983686  alpha-(1,6)-fucosyltransferase-like [KO:K00717] [EC:2.4.1.68]
127933373  alpha-(1,6)-fucosyltransferase-like [KO:K00717] [EC:2.4.1.68]
127976039  alpha-(1,6)-fucosyltransferase-like [KO:K00717] [EC:2.4.1.68]
127938087  alpha-(1,6)-fucosyltransferase-like [KO:K00717] [EC:2.4.1.68]
127971459  beta-1,4-galactosyltransferase 1 isoform X1 [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
127976547  beta-1,4-galactosyltransferase 1-like [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
127949703  beta-1,4-galactosyltransferase 1-like [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
128027614  beta-1,4-galactosyltransferase 1-like [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
128027620  beta-1,4-galactosyltransferase 1-like [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
127951700  beta-1,4-galactosyltransferase 2-like [KO:K07967] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
128030792  beta-1,4-galactosyltransferase 2-like [KO:K07967] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
127944238  beta-1,4-galactosyltransferase 3-like [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
127975011  beta-1,4-galactosyltransferase 3-like [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
128011322  beta-1,4-galactosyltransferase 3 isoform X1 [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
128030701  si:dkey-199f5.8; beta-1,4-galactosyltransferase 3 [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
127942088  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2-like [KO:K00741] [EC:2.4.1.149]
127976516  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2-like [KO:K00741] [EC:2.4.1.149]
127949283  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2-like isoform X1 [KO:K00741] [EC:2.4.1.149]
128031743  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2-like [KO:K00741] [EC:2.4.1.149]
127985489  si:dkey-175m17.6; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 [KO:K00741] [EC:2.4.1.149]
128027136  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2-like [KO:K00741] [EC:2.4.1.149]
128020143  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2-like isoform X1 [KO:K00741] [EC:2.4.1.149]
127946803  carbohydrate sulfotransferase 6 [KO:K09671] [EC:2.8.2.-]
128014369  carbohydrate sulfotransferase 6-like [KO:K09671] [EC:2.8.2.-]
127958879  beta-1,4-galactosyltransferase 4 [KO:K07969] [EC:2.4.1.90 2.4.1.275 2.4.1.-]
127991291  beta-1,4-galactosyltransferase 4-like [KO:K07969] [EC:2.4.1.90 2.4.1.275 2.4.1.-]
127942588  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7-like [KO:K09664] [EC:2.4.1.-]
127962885  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7-like [KO:K09664] [EC:2.4.1.-]
127987282  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [KO:K09664] [EC:2.4.1.-]
128018718  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7-like [KO:K09664] [EC:2.4.1.-]
127934707  carbohydrate sulfotransferase 1-like [KO:K01022] [EC:2.8.2.21]
127946787  carbohydrate sulfotransferase 1-like [KO:K01022] [EC:2.8.2.21]
127977923  si:ch73-62b13.1; carbohydrate sulfotransferase 1-like [KO:K01022] [EC:2.8.2.21]
128014724  carbohydrate sulfotransferase 1 [KO:K01022] [EC:2.8.2.21]
127951046  ST3 beta-galactoside alpha-2,3-sialyltransferase 3b isoform X1 [KO:K00781] [EC:2.4.3.6]
127960173  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase-like isoform X1 [KO:K00781] [EC:2.4.3.6]
128015249  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase-like isoform X1 [KO:K00781] [EC:2.4.3.6]
128026497  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase-like isoform X1 [KO:K00781] [EC:2.4.3.6]
127946426  carbohydrate sulfotransferase 2-like [KO:K04745] [EC:2.8.2.-]
127950873  carbohydrate sulfotransferase 2-like [KO:K04745] [EC:2.8.2.-]
128013512  carbohydrate sulfotransferase 2-like [KO:K04745] [EC:2.8.2.-]
128025866  carbohydrate sulfotransferase 2-like [KO:K04745] [EC:2.8.2.-]
127957433  CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1-like [KO:K00780] [EC:2.4.3.2 2.4.3.4]
127934635  CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 2-like [KO:K03368] [EC:2.4.3.2 2.4.3.4]
127977328  CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 2-like [KO:K03368] [EC:2.4.3.2 2.4.3.4]
Reference
PMID:11030741
  Authors
Funderburgh JL.
  Title
Keratan sulfate: structure, biosynthesis, and function.
  Journal
Glycobiology 10:951-958 (2000)
DOI:10.1093/glycob/10.10.951
Reference
PMID:14706853
  Authors
Seko A, Yamashita K.
  Title
beta1,3-N-Acetylglucosaminyltransferase-7 (beta3Gn-T7) acts efficiently on keratan sulfate-related glycans.
  Journal
FEBS Lett 556:216-20 (2004)
DOI:10.1016/S0014-5793(03)01440-6
Reference
PMID:12511560
  Authors
Seko A, Dohmae N, Takio K, Yamashita K.
  Title
Beta 1,4-galactosyltransferase (beta 4GalT)-IV is specific for GlcNAc 6-O-sulfate. Beta 4GalT-IV acts on keratan sulfate-related glycans and a precursor glycan of 6-sulfosialyl-Lewis X.
  Journal
J Biol Chem 278:9150-8 (2003)
DOI:10.1074/jbc.M211480200
Related
pathway
cgib00510  N-Glycan biosynthesis
cgib00512  Mucin type O-glycan biosynthesis
KO pathway
ko00533   
LinkDB

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