KEGG ORTHOLOGY: K00780

ORTHOLOGY: K00780

Entry

K00780                      KO

Symbol

ST3GAL1

Name

beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.3.2 2.4.3.4]

Pathway

map00512

Mucin type O-glycan biosynthesis

map00533

Glycosaminoglycan biosynthesis - keratan sulfate

map00603

Glycosphingolipid biosynthesis - globo and isoglobo series

map00604

Glycosphingolipid biosynthesis - ganglio series

map01100

Metabolic pathways

Reaction

R05913

R05942

R05949

R05957

R05967

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00512 Mucin type O-glycan biosynthesis
    K00780  ST3GAL1; beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A)
   00533 Glycosaminoglycan biosynthesis - keratan sulfate
    K00780  ST3GAL1; beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A)
   00603 Glycosphingolipid biosynthesis - globo and isoglobo series
    K00780  ST3GAL1; beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A)
   00604 Glycosphingolipid biosynthesis - ganglio series
    K00780  ST3GAL1; beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00780  ST3GAL1; beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A)
Enzymes [BR:ko01000]
2. Transferases
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.2  beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase
     K00780  ST3GAL1; beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A)
    2.4.3.4  beta-galactoside alpha-2,3-sialyltransferase
     K00780  ST3GAL1; beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A)
Glycosyltransferases [BR:ko01003]
Terminal extension
  Sialyltransferase
   K00780  ST3GAL1; beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A)
Glycosyltransferase reactions [br08203.html]
Sialyltransferase reactions
  K00780

Other DBs

GO:

0003836

CAZy:

GT29

Genes

HSA:	6482(ST3GAL1)

PTR:	450114(ST3GAL1)

PPS:	100987531(ST3GAL1)

GGO:	101152668(ST3GAL1)

PON:	100438644(ST3GAL1)

PPYG:

129042320(ST3GAL1)

NLE:	100583104(ST3GAL1)

HMH:	116813607(ST3GAL1)

SSYN:

129486841(ST3GAL1)

MCC:	698004(ST3GAL1)

MCF:	102127575(ST3GAL1)

MTHB:

126961676

MNI:	105492840(ST3GAL1)

CSAB:

103237477(ST3GAL1)

CATY:

105588352(ST3GAL1)

PANU:

101016088(ST3GAL1)

TGE:	112630265(ST3GAL1)

MLEU:

105537480(ST3GAL1)

RRO:	104675666(ST3GAL1)

RBB:	108531600(ST3GAL1)

TFN:	117079253(ST3GAL1)

PTEH:

111550253(ST3GAL1)

CANG:

105509048(ST3GAL1)

CJC:	100400713(ST3GAL1)

SBQ:	101039394(ST3GAL1)

CIMI:

108283561(ST3GAL1)

ANAN:

105723790(ST3GAL1)

CSYR:

103264317(ST3GAL1)

MMUR:

105882778(ST3GAL1)

LCAT:

123644309(ST3GAL1)

PCOQ:

105813436(ST3GAL1)

OGA:	100966471(ST3GAL1)

MMU:	20442(St3gal1)

MCAL:

110310896(St3gal1)

MPAH:

110334937(St3gal1)

RNO:	362924(St3gal1)

MCOC:

116082717(St3gal1)

ANU:	117718586(St3gal1)

ASYL:

127668173(St3gal1)

MUN:	110563938(St3gal1)

CGE:

113830645

MAUA:

101828923(St3gal1)

PROB:

127235263(St3gal1)

PLEU:

114697712(St3gal1)

MORG:

121461291(St3gal1)

MFOT:

126503310

AAMP:

119822368(St3gal1)

NGI:	103728440(St3gal1)

HGL:	101720225(St3gal1)

CPOC:

100720961(St3gal1)

CCAN:

109693253(St3gal1)

DORD:

105992352(St3gal1)

DSP:	122125365(St3gal1)

PLOP:

125360695(St3gal1)

NCAR:

124983433

MMMA:

107142936(St3gal1)

ITI:	101975814(St3gal1)

OCU:

100339631

OPI:	101525814(ST3GAL1)

TUP:	102475684(ST3GAL1)

GVR:	103593827 103601040(ST3GAL1)

CFA:	482050(ST3GAL1)

CLUD:

112662040(ST3GAL1)

VVP:	112915992(ST3GAL1)

VLG:	121499124(ST3GAL1)

NPO:	129502431(ST3GAL1)

AML:	100467054(ST3GAL1)

UMR:	103656747(ST3GAL1)

UAH:	113252698(ST3GAL1)

UAR:	123801924(ST3GAL1)

ELK:

111146617

LLV:

125096805

MPUF:

101675267(ST3GAL1)

MNP:	132014316(ST3GAL1)

MLK:	131826382(ST3GAL1)

NVS:	122904284(ST3GAL1)

ORO:	101370180(ST3GAL1)

EJU:	114211147(ST3GAL1)

ZCA:	113931017(ST3GAL1)

MLX:	118015233(ST3GAL1)

NSU:	110578948(ST3GAL1)

LWW:	102747658(ST3GAL1)

FCA:	101089330(ST3GAL1)

PYU:	121043082(ST3GAL1)

PCOO:

112859725(ST3GAL1)

PBG:	122495837(ST3GAL1)

PVIV:

125156693(ST3GAL1)

LRUF:

124507830

LGF:	123585428(ST3GAL1)

AJU:

106971497

PTG:	102950618(ST3GAL1)

PPAD:

109273094(ST3GAL1)

PUC:

125924719

PLEZ:

122211070(ST3GAL1)

HHV:	120237048(ST3GAL1)

BTA:	282351(ST3GAL1)

BOM:	102267241(ST3GAL1)

BIU:	109568527(ST3GAL1)

BBUB:

102416340(ST3GAL1)

BBIS:

104984848(ST3GAL1)

CHX:	102180329(ST3GAL1)

OAS:	101122606(ST3GAL1)

BTAX:

128059100(ST3GAL1)

CSUM:

138088238(ST3GAL1)

ODA:	120879055(ST3GAL1)

CCAD:

122450847(ST3GAL1)

MREE:

136144775(ST3GAL1)

OVR:	110148648(ST3GAL1)

MBEZ:

129560496(ST3GAL1)

SSC:	445537(ST3GAL1)

CFR:	102516304(ST3GAL1)

CBAI:

105082956(ST3GAL1)

CDK:	105096461(ST3GAL1)

VPC:	102537485(ST3GAL1)

BACU:

102998657(ST3GAL1)

BMUS:

118883441(ST3GAL1)

LVE:	103088944(ST3GAL1)

OOR:	101270756(ST3GAL1)

LALB:

132508421(ST3GAL1)

DLE:	111165172(ST3GAL1)

PCAD:

102987290(ST3GAL1)

PSIU:

116742172(ST3GAL1)

NASI:

112396999(ST3GAL1)

ECB:	100069007(ST3GAL1)

EPZ:	103555856(ST3GAL1)

EAI:	106824816(ST3GAL1)

MYB:	102244244(ST3GAL1)

MYD:	102757000(ST3GAL1)

MMYO:

118670579(ST3GAL1)

MLF:	102420218(ST3GAL1)

MDT:	132219766(ST3GAL1)

MYUM:

138993260(ST3GAL1)

PKL:	118718648(ST3GAL1)

EFUS:

103299752(ST3GAL1)

MNA:	107539559(ST3GAL1)

DRO:	112315489(ST3GAL1)

SHON:

118988696(ST3GAL1)

AJM:	119064792(ST3GAL1)

PDIC:

114514682(ST3GAL1)

PHAS:

123833109(ST3GAL1)

PPAM:

129084340(ST3GAL1)

HAI:	109387429(ST3GAL1)

RFQ:	117033812(ST3GAL1)

PALE:

102898997(ST3GAL1)

PGIG:

120588731(ST3GAL1)

PVP:	105299394(ST3GAL1)

RAY:	107511329(ST3GAL1)

MJV:	108399236(ST3GAL1)

TOD:	119237524(ST3GAL1)

SARA:

101553922(ST3GAL1)

SFUM:

130021402(ST3GAL1)

SETR:

125997124(ST3GAL1)

LAV:	100667581(ST3GAL1)

TMU:

101353731

ETF:	101649658(ST3GAL1)

DNM:	101439342(ST3GAL1)

MDO:	100032599(ST3GAL1)

GAS:	123255647(ST3GAL1)

SHR:	100924982(ST3GAL1)

AFZ:

127544472

PCW:	110216084(ST3GAL1)

TVP:	118845859(ST3GAL1)

PBRV:

138155918(ST3GAL1)

OAA:	100081042(ST3GAL1)

TACU:

119940324(ST3GAL1)

GGA:	396140(ST3GAL1)

PCOC:

116227762(ST3GAL1)

MGP:	100550797(ST3GAL1)

CJO:	107310569(ST3GAL1)

TPAI:

128090866(ST3GAL1)

LMUT:

125690924(ST3GAL1)

NMEL:

110393609(ST3GAL1)

APLA:

101790636(ST3GAL1)

ACYG:

106043283(ST3GAL1)

CATA:

118255469(ST3GAL1)

AFUL:

116486098(ST3GAL1)

TGU:	100224643(ST3GAL1)

LSR:	110477007(ST3GAL1)

SCAN:

103814648(ST3GAL1)

PMOA:

120505163(ST3GAL1)

OTC:	121337464(ST3GAL1)

PRUF:

121359946(ST3GAL1)

ATRC:

139587471(ST3GAL1)

GFR:	102033897(ST3GAL1)

FAB:	101811246(ST3GAL1)

OMA:	130249798(ST3GAL1)

PHI:	102106597(ST3GAL1)

PMAJ:

107200730(ST3GAL1)

CCAE:

111925076(ST3GAL1)

CCW:	104692627(ST3GAL1)

CBRC:

103619017(ST3GAL1)

ACOE:

138105485(ST3GAL1)

ETL:	114066593(ST3GAL1)

ZAB:	102063168(ST3GAL1)

ZLE:	135444682(ST3GAL1)

ACHL:

103804333(ST3GAL1)

SVG:	106856641(ST3GAL1)

MMEA:

130581206(ST3GAL1)

HRT:	120761191(ST3GAL1)

SATI:

136371969(ST3GAL1)

CCIC:

134043482(ST3GAL1)

FPG:	101915219(ST3GAL1)

FCH:	102059972(ST3GAL1)

CCRI:

104167538(ST3GAL1)

NNT:	104410944(ST3GAL1)

SHAB:

115608134(ST3GAL1)

ACUN:

113476242(ST3GAL1)

TALA:

104360705(ST3GAL1)

ACHC:

115340841(ST3GAL1)

HALD:

104319137(ST3GAL1)

HLE:	104837648(ST3GAL1)

AGEN:

126047779

HHAR:

128141990(ST3GAL1)

GCL:

127029987

LDI:	104354157(ST3GAL1)

MNB:	103771815(ST3GAL1)

DPUB:

104301555(ST3GAL1)

PPUS:

135181285(ST3GAL1)

AVIT:

104280023(ST3GAL1)

BRHI:

104499756(ST3GAL1)

EGZ:	104134451(ST3GAL1)

NNI:	104016852(ST3GAL1)

PCRI:

104035546(ST3GAL1)

PCAO:

104047352(ST3GAL1)

PADL:

103916389(ST3GAL1)

AFOR:

103894562(ST3GAL1)

FGA:

104071643

GSTE:

104263153

CLV:	102084549(ST3GAL1)

MUI:	104548163(ST3GAL1)

PGUU:

104459940(ST3GAL1)

PLET:

104628369

EHS:	104509491(ST3GAL1)

CMAC:

104474974(ST3GAL1)

CUCA:

104058497(ST3GAL1)

TEO:	104376213(ST3GAL1)

BREG:

104629386(ST3GAL1)

OHA:	104333514(ST3GAL1)

ACAR:

104526830(ST3GAL1)

CPEA:

104393996(ST3GAL1)

CVF:	104292701(ST3GAL1)

RTD:	128906371(ST3GAL1)

CRID:

134512267(ST3GAL1)

AAM:	106496288(ST3GAL1)

AROW:

112961677(ST3GAL1)

NPD:	112951270(ST3GAL1)

TGT:	104576543(ST3GAL1)

DNE:	112991290(ST3GAL1)

SCAM:

104140614(ST3GAL1)

ASN:	102376781(ST3GAL1)

AMJ:	102572981(ST3GAL1)

CPOO:

109322138(ST3GAL1)

GGN:	109305212(ST3GAL1)

PSS:	102456540(ST3GAL1)

CMY:	102942769(ST3GAL1)

CCAY:

125632862(ST3GAL1)

DCC:	119850925(ST3GAL1)

CPIC:

101932394(ST3GAL1)

TST:	117873832(ST3GAL1)

CABI:

116820761(ST3GAL1)

MRV:	120398042(ST3GAL1)

ACS:	100553436(st3gal1)

ASAO:

132775123(ST3GAL1)

PVT:	110085871(ST3GAL1)

SUND:

121927988(ST3GAL1)

PBI:	103056646(ST3GAL1)

PMUR:

107299399(ST3GAL1) 107301072

CTIG:

120311229(ST3GAL1)

TSR:	106541007(ST3GAL1)

PGUT:

117675817(ST3GAL1)

APRI:

131194092(ST3GAL1)

PTEX:

113438337(ST3GAL1)

NSS:	113419241(ST3GAL1)

VKO:	123033683(ST3GAL1)

PMUA:

114600231(ST3GAL1)

PRAF:

128417063(ST3GAL1)

ZVI:	118090445(ST3GAL1)

HCG:	128323048(ST3GAL1)

GJA:	107126269(ST3GAL1)

STOW:

125439480(ST3GAL1)

EMC:	129333094(ST3GAL1)

XLA:	108695455(st3gal1.S) 108719427(st3gal1.L)

XTR:	100329190(st3gal1)

NPR:	108792323(ST3GAL1)

RTEM:

120941548(ST3GAL1)

BBUF:

121001212(ST3GAL1)

PWL:	138282840(ST3GAL1)

MUO:	115459609 115480611(ST3GAL1)

GSH:	117355162(ST3GAL1)

SRX:

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

LROH:

OMC:

MASI:

TROS:

130567422(st3gal1l3)

TDW:

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

103036550(st3gal1l3)

CMAO:

EEE:

CHAR:

SPIL:

TRU:	446079(st3gal1)

TFS:

LCO:

NCC:

TBEN:

CGOB:

PGEO:

117454746(st3gal1)

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

SCHU:

CUD:

SPUL:

LMIX:

ALAT:

ASTR:

MZE:

ONL:

OAU:

OLA:	100049378(st3gal1)

OML:	112136318(st3gal1l3)

CSAI:

133423941

XMA:	102230934(st3gal1)

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:	124879555 124879683

NFU:

KMR:

NWH:

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

103394178(st3gal1)

POV:	109631673(st3gal1)

SSEN:

122786116(st3gal1l2)

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

ENY:	140361427 140361857

MALB:

BSPL:

SJO:

SSCO:

GMH:	115535912 115535967

SASA:

106570220 106588596

STRU:

115166805 115173205 115173724 115175752 115204572 115204573

OTW:	112229662 112264645

OMY:	110488197 110496379

OGO:	124006696 124012050 124013218 124022803 124026744 124035490

ONE:	115125258 115128521 115131480 115146848

OKI:	109874382 109883165 109903523 109907403 116352874

OKE:	118371755 118378704 118379391 118399462 127909345

OMM:	135537713 135537714 135549831 135552077

OCLA:

139372661 139373563 139388446 139392289 139396672

SALP:

111955199 111956066

SNH:	120022419 120027304 120027435

CCLU:

121541998 121548166 121571956 121585595

ELS:	105012755(st3gal1)

OEP:

134006680

SFM:	108919256 114909397 114909398

PKI:	111843952(st3gal1)

AANG:

118233925

AROT:

135261691

LOC:	102689819(st3gal1)

PSPA:

121313692 121314019

ARUT:

117399438 117435447

PSEX:

120515892

LCM:	102345200(st3gal1A)

CMK:

RTP:

CPLA:

HOC:

LERI:

LRJ:

LPIC:

AAMU:

Reference

PMID:1383214

Authors

Gillespie W, Kelm S, Paulson JC

Title

Cloning and expression of the Gal beta 1, 3GalNAc alpha 2,3-sialyltransferase.

Journal

J Biol Chem 267:21004-10 (1992)
DOI:10.1016/S0021-9258(19)36789-4

Sequence

[ssc:445537]

LinkDB

DBGET integrated database retrieval system