KEGG   Homo sapiens (human): 10274
Entry
10274             CDS       T01001                                 
Symbol
STAG1, MRD47, SA1, SCC3A
Name
(RefSeq) STAG1 cohesin complex component
  KO
K06671  cohesin complex subunit SA-1/2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06512  Chromosome cohesion and segregation
  Element
N01482  Cohesin loading
N01484  Establishment of cohesion
N01485  Cohesin dissociation in prophase
Disease
H00773  Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    10274 (STAG1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    10274 (STAG1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Sister chromatid cohesion proteins
   Cohesin complex
    10274 (STAG1)
SSDB
Motif
Pfam: STAG SCD RFX5_DNA_bdg Cnd3
Other DBs
NCBI-GeneID: 10274
NCBI-ProteinID: NP_005853
OMIM: 604358
HGNC: 11354
Ensembl: ENSG00000118007
Pharos: Q8WVM7(Tbio)
UniProt: Q8WVM7 Q4LE48
Structure
LinkDB
Position
3:complement(136336236..136752378)
AA seq 1258 aa
MITSELPVLQDSTNETTAHSDAGSELEETEVKGKRKRGRPGRPPSTNKKPRKSPGEKSRI
EAGIRGAGRGRANGHPQQNGEGEPVTLFEVVKLGKSAMQSVVDDWIESYKQDRDIALLDL
INFFIQCSGCRGTVRIEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMPGPQWKKFRSNFCE
FIGVLIRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNL
SIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRY
RDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTN
RELFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLV
YSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEH
AAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAH
PPVGRGTGKRVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFD
LEIYSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKTYSILCSEEYTIQNRVDIARSQ
LIDEFVDRFNHSVEDLLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLL
KTGIEHGAMPEQIVVQALQCSHYSILWQLVKITDGSPSKEDLLVLRKTVKSFLAVCQQCL
SNVNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFID
QDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDY
GDIIKETLSKTRQIDKIQCAKTLILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFA
LTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKK
TVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSSSKTSSVRNKKG
RPPLHKKRVEDESLDNTWLNRTDTMIQTPGPLPAPQLTSTVLRENSRPMGDQIQEPESEH
GSEPDFLHNPQMQISWLGQPKLEDLNRKDRTGMNYMKVRTGVRHAVRGLMEEDAEPIFED
VMMSSRSQLEDMNEEFEDTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGFGMPMF
NT seq 3777 nt   +upstreamnt  +downstreamnt
atgattacttcagaattaccagtgttacaggattcaactaatgaaactactgcccattcc
gatgctggcagcgagcttgaagaaacagaggtcaaaggaaaaagaaaaaggggtcgtcct
ggccggcctccatctacaaataagaaacctcgaaaatctccaggtgagaagagcagaatt
gaagctggaattagaggagcaggccgtggaagagctaatggacaccctcaacagaatggg
gaaggggagcctgtcacattatttgaggtggtgaaactggggaaaagtgcaatgcagtcc
gtggtggatgactggattgaatcatataaacaagacagggacatcgcacttctggattta
atcaacttttttatccagtgttcaggatgtcgaggtactgtgagaatagagatgtttcga
aatatgcagaatgcagaaatcatcagaaaaatgactgaagaatttgatgaggacagtggt
gattatcctcttaccatgcctggacctcagtggaaaaaatttcgttcaaacttttgtgaa
tttattggagtcctgattcgacagtgtcagtatagcataatttatgatgagtatatgatg
gacacagtaatctcccttttgacgggtttgtcagactcccaggtcagagcttttaggcat
acaagtaccctggctgccatgaagctcatgactgctctggtgaatgttgccttaaacctc
agtattcatcaggataatacccagagacaatatgaagccgagagaaataaaatgattggg
aagagagccaatgaaaggttggagttactacttcagaaacgcaaagagctgcaagaaaat
caggatgaaatcgaaaatatgatgaactctatttttaagggtatatttgttcatagatac
cgtgatgctattgctgagattagagccatttgtattgaagaaattggagtatggatgaaa
atgtatagtgatgccttcctaaatgacagttacctaaaatatgttggctggactcttcat
gacaggcaaggggaagtcaggctgaagtgtttgaaagctctgcagagtctatataccaat
agagaattattccccaaattggaactattcactaaccgattcaaggatcgcattgtatca
atgacacttgataaagaatatgatgttgctgtggaagctattcgattggttactctgata
cttcatggaagtgaagaagctctttccaatgaagactgtgaaaatgtttaccacttggtg
tactcggcacatcgccctgttgctgtggcagctggagagttccttcacaaaaagctattt
agcagacatgacccacaagcagaagaagcattagcaaagaggaggggaagaaacagcccg
aatggaaacctcattaggatgctggttcttttctttcttgaaagtgagttacatgaacat
gcagcctacttggtggacagtttatgggagagctctcaagaactgttgaaagactgggaa
tgtatgacagagttgctattagaagaacctgttcaaggagaggaagcaatgtctgatcgt
caagagagtgctcttatagagctaatggtttgtacaattcgtcaagctgctgaggcacat
cctccagtgggaaggggtaccggcaagagagtgctaactgccaaagaaaggaaaactcaa
attgatgatagaaacaaattgactgaacattttattattacacttcctatgttactgtca
aagtattctgcagatgcagagaaggtagcaaacttgctacaaatcccacagtattttgat
ttagaaatctacagcacaggtagaatggaaaagcatctggatgctttattaaaacagatt
aagtttgttgtggagaaacacgtagaatcagatgttctagaagcctgcagtaaaacctat
agtatcttatgcagtgaagaatataccatccagaacagagttgacatagctcgaagccag
ctgattgatgagtttgtagatcgattcaatcattctgtggaagacctattgcaagaggga
gaagaagctgatgatgatgacatttacaatgttctttctacattaaagcggttaacttct
tttcacaatgcacatgatctcacaaaatgggatctctttggtaattgctacagattattg
aagactggaattgaacatggagccatgccagaacagatagtcgtgcaagcactgcagtgt
tcccattattcgattctttggcagttggtgaaaattactgatggctctccttccaaagag
gatttgttggtattgaggaaaacggtgaaatcctttttggctgtttgccagcagtgcctg
tctaatgttaatactccagtgaaagaacaggctttcatgttactctgtgatcttctgatg
attttcagccaccaattaatgacaggtggcagagagggccttcagcctttggtgttcaat
ccagatactggactccaatctgaactcctcagttttgtgatggatcacgtttttattgac
caagacgaggagaaccagagcatggagggtgatgaagaagatgaagctaataaaattgag
gccttacataaaagaaggaatctacttgctgctttcagcaaacttatcatttatgacatt
gttgacatgcatgcagctgcagacatcttcaaacactacatgaagtattacaatgactat
ggtgatattattaaggaaacactgagtaaaaccaggcagattgataaaattcagtgtgcc
aagactctcattctcagtttgcaacagttatttaatgaacttgttcaagagcaaggtccc
aacctagataggacatctgcccatgtcagtggcattaaagaactggcacgtcgctttgcc
cttacatttggattggaccagattaagacacgagaagcagttgccacacttcacaaggat
ggcatagagtttgcatttaaataccaaaatcagaaaggacaagagtatccacctcctaat
ctggcttttcttgaagtactaagtgaattttcttctaaacttcttcgacaggacaaaaag
acagttcattcatacctagagaaattccttaccgagcagatgatggaaaggagggaggat
gtatggcttccactcatctcctatagaaattcattagtcactgggggtgaagatgataga
atgtctgtgaacagtggaagtagcagcagcaaaacctcatcagtaaggaataagaaagga
cgacctccacttcataaaaaacgagtagaagatgagagtctggataacacatggctaaac
aggactgacaccatgattcagactcctggccccctgccagcaccacaactcacatccact
gtactgcgggagaacagtcggcccatgggagaccagattcaagaacctgagtctgaacat
ggttctgaaccagactttttacacaatcctcagatgcagatctcttggttaggccagccg
aagttagaagacttaaatcggaaggacagaacaggaatgaactacatgaaagtgagaact
ggagtgaggcatgctgttcggggtctaatggaggaagatgctgagcccatctttgaagat
gtgatgatgtcatcccgaagccagttagaagatatgaatgaagaatttgaggacaccatg
gttattgatctgcctccatcaagaaatcggcgagagagagctgagctaaggccagacttc
tttgactctgcagctatcatagaagatgattcaggatttggaatgcctatgttctga

KEGG   Homo sapiens (human): 10735
Entry
10735             CDS       T01001                                 
Symbol
STAG2, HPE13, MKMS, NEDXCF, SA-2, SA2, SCC3B, bA517O1.1
Name
(RefSeq) STAG2 cohesin complex component
  KO
K06671  cohesin complex subunit SA-1/2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06512  Chromosome cohesion and segregation
  Element
N01482  Cohesin loading
N01484  Establishment of cohesion
N01485  Cohesin dissociation in prophase
Disease
H00267  Holoprosencephaly
H02582  Mullegama-Klein-Martinez syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    10735 (STAG2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    10735 (STAG2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Sister chromatid cohesion proteins
   Cohesin complex
    10735 (STAG2)
SSDB
Motif
Pfam: STAG SCD Cnd3 AdoHcyase_NAD
Other DBs
NCBI-GeneID: 10735
NCBI-ProteinID: NP_001036216
OMIM: 300826
HGNC: 11355
Ensembl: ENSG00000101972
Pharos: Q8N3U4(Tbio)
UniProt: Q8N3U4 Q6MZM3
Structure
LinkDB
Position
X:123960560..124102656
AA seq 1231 aa
MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG
GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF
FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG
VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN
MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA
IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL
NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA
HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL
VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG
RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY
TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE
LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI
ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN
TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD
NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII
KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG
LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV
YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG
KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS
VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP
SKNRRERTELKPDFFDPASIMDESVLGVSMF
NT seq 3696 nt   +upstreamnt  +downstreamnt
atgatagcagctccagaaataccaactgattttaatctactacaggagtcagaaacacat
ttttcttctgacacagattttgaagatatcgaaggaaaaaaccaaaagcaaggcaaaggc
aaaacttgtaaaaaaggcaaaaagggcccagcagaaaagggcaaaggtggaaatggagga
ggaaaacctccttctggtccaaaccgaatgaatggtcatcaccaacagaatggagtggaa
aacatgatgttgtttgaagttgttaaaatgggcaagagtgctatgcagtcggtggtagat
gattggatagaatcatacaagcatgaccgagatatagcacttcttgaccttatcaacttt
tttattcagtgttcaggctgtaaaggagttgtcacagcagaaatgtttagacatatgcag
aactctgagataattcgaaaaatgactgaagaattcgatgaggatagtggagattatcca
cttaccatggctggtcctcagtggaagaagttcaaatccagtttttgtgaattcattggc
gtgttagtacggcaatgtcaatatagtatcatatatgatgagtatatgatggatacagtc
atttcacttcttacaggattgtctgactcacaagtcagagcatttcgacatacaagcacc
ctggcagctatgaagttgatgacagctttggtgaatgtggcactaaatcttagcattaat
atggataatacacaaagacaatatgaagcagaacggaataaaatgattggaaaacgagcc
aatgagaggctagaactcctgctacaaaagcggaaagagcttcaggaaaatcaagatgaa
atagaaaatatgatgaatgcaatatttaaaggagtgtttgtacatagataccgtgatgcg
atagctgaaattcgagctatttgcattgaagagattggcatttggatgaagatgtatagt
gatgcctttcttaatgacagttatttaaaatatgttggttggactatgcatgataagcaa
ggtgaagtaagactcaaatgtcttactgctctacaagggctttattataacaaagagctt
aattccaaactggaactttttaccagtcggttcaaggatagaattgtgtctatgaccctt
gacaaagaatatgatgttgcagtacaagcaataaaattactcactcttgttttacagagt
agtgaagaagttctcactgcagaagattgtgaaaatgtctatcatctggtttattcagct
caccggccagtagcagtagcagctggagaatttctctacaaaaagctcttcagtcgtaga
gatccagaggaggatggaatgatgaaaagaagaggaagacaaggtccaaatgccaacctt
gttaagacattggtttttttctttctagaaagtgagttacatgagcatgcagcatacctt
gtggatagcatgtgggactgtgctactgagctgctgaaagactgggaatgtatgaatagc
ttgttactggaagagccacttagtggagaggaagcactaacagataggcaagagagtgct
ctgattgaaataatgctttgtaccattagacaagcggctgaatgtcatcctcccgtggga
agagggacaggaaaaagggtgcttacagcaaaggagaagaagacacagttggatgatagg
acaaaaatcactgagctttttgccgtggcccttcctcagttattagcaaaatactctgta
gatgcagaaaaggtgactaacttgttgcagttgcctcagtactttgatttggaaatatat
accactggacgattagaaaagcatttggatgccttattgcgacagatccggaatattgta
gagaagcacacagatacagatgttttggaagcatgttctaaaacttaccatgcactctgt
aatgaagagttcacaatcttcaacagagtagatatttcaagaagtcaactgatagatgaa
ttggcagataaatttaaccggcttcttgaagattttctgcaagagggtgaagaacctgat
gaagatgatgcatatcaggtattgtcaacattgaagaggatcactgcttttcataatgcc
catgacctttcaaagtgggatttatttgcttgtaattacaaactcttgaaaactggaatc
gaaaatggagacatgcctgagcagattgttattcacgcactgcagtgtactcactatgta
atcctttggcaacttgctaagataactgaaagcagctctacaaaggaggacttgctgcgt
ttaaagaaacaaatgagagtattttgtcagatatgtcaacattacctgaccaacgtgaat
actactgttaaggaacaggccttcactattctgtgtgatattttgatgatcttcagccat
cagattatgtcaggagggcgtgacatgttagagccattagtgtatacccctgattcttca
ttgcagtctgagttgctcagctttattttggatcatgtcttcattgaacaggatgatgat
aataatagtgcagatggtcagcaagaggatgaagccagtaaaattgaagctctgcacaag
agaagaaatttacttgcagcattttgtaagctaattgtatatactgtggtggagatgaat
acagctgcagatatcttcaaacagtatatgaagtattataatgactatggagatatcatc
aaagaaacaatgagtaaaacaaggcagatagacaaaattcagtgtgctaagacccttatt
ctcagtctgcaacagctttttaatgaaatgatacaagaaaatggctataattttgataga
tcatcctctacatttagtggcataaaagaacttgctcgacgttttgctttaacttttgga
cttgatcagttgaaaacaagagaagccattgccatgctacacaaagatggcatagaattt
gcttttaaagagcctaatccgcaaggggagagccatccacctttaaatttggcatttctt
gatattctgagtgaattttcttctaaactacttcgacaagacaaaagaacagtgtatgtt
tacttggaaaagttcatgacctttcagatgtcactccgaagagaggatgtgtggcttcca
ctgatgtcttaccgaaattctttgctagctggtggtgatgatgacaccatgtcagtcatt
agtggaatcagcagccgggggtcaacagtacggagtaaaaaatcaaaaccatctacagga
aaacggaaagtggttgagggcatgcagctttcactcactgaagaaagtagtagtagtgac
agtatgtggttaagcagagaacaaacactgcacacccctgttatgatgcagacaccacaa
ctcacctccactattatgagagagcccaaaagattacggcctgaggatagcttcatgagt
gtttatccaatgcagactgaacatcatcaaacacctcttgattataatcggcgtggcaca
agcctaatggaagatgatgaagagccaattgtggaagatgttatgatgtcctcagaaggg
aggattgaggatcttaatgagggaatggattttgacaccatggatatagatttgccacca
tcaaagaacagacgagagagaacagaactgaagcctgatttctttgatccagcttcaatt
atggatgaatcagttcttggagtgtcaatgttttaa

KEGG   Homo sapiens (human): 113130
Entry
113130            CDS       T01001                                 
Symbol
CDCA5, SORORIN
Name
(RefSeq) cell division cycle associated 5
  KO
K17390  sororin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa05206  MicroRNAs in cancer
Network
nt06512  Chromosome cohesion and segregation
  Element
N01483  Cohesin acetylation
N01484  Establishment of cohesion
N01485  Cohesin dissociation in prophase
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    113130 (CDCA5)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    113130 (CDCA5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    113130 (CDCA5)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Sister chromatid cohesion proteins
   Other sister chromatid cohesion factors
    113130 (CDCA5)
SSDB
Motif
Pfam: Sororin
Other DBs
NCBI-GeneID: 113130
NCBI-ProteinID: NP_542399
OMIM: 609374
HGNC: 14626
Ensembl: ENSG00000146670
Pharos: Q96FF9(Tbio)
UniProt: Q96FF9
LinkDB
Position
11:complement(65061093..65084040)
AA seq 252 aa
MSGRRTRSGGAAQRSGPRAPSPTKPLRRSQRKSGSELPSILPEIWPKTPSAAAVRKPIVL
KRIVAHAVEVPAVQSPRRSPRISFFLEKENEPPGRELTKEDLFKTHSVPATPTSTPVPNP
EAESSSKEGELDARDLEMSKKVRRSYSRLETLGSASTSTPGRRSCFGFEGLLGAEDLSGV
SPVVCSKLTEVPRVCAKPWAPDMTLPGISPPPEKQKRKKKKMPEILKTELDEWAAAMNAE
FEAAEQFDLLVE
NT seq 759 nt   +upstreamnt  +downstreamnt
atgtctgggaggcgaacgcggtccggaggagccgctcagcgctccgggccaagggcccca
tctcctactaagcctctgcggaggtcccagcggaaatcaggctctgaactcccgagcatc
ctccctgaaatctggccgaagacacccagtgcggctgcagtcagaaagcccatcgtctta
aagaggatcgtggcccatgctgtagaggtcccagctgtccaatcacctcgcaggagccct
aggatttcctttttcttggagaaagaaaacgagccccctggcagggagcttactaaggag
gaccttttcaagacacacagcgtccctgccacccccaccagcactcctgtgccgaaccct
gaggccgagtccagctccaaggaaggagagctggacgccagagacttggaaatgtctaag
aaagtcaggcgttcctacagccggctggagaccctgggctctgcctctacctccacccca
ggccgccggtcctgctttggcttcgaggggctgctgggggcagaagacttgtccggagtc
tcgccagtggtgtgctccaaactcaccgaggtccccagggtttgtgcaaagccctgggcc
ccagacatgactctccctggaatctccccaccacccgagaaacagaaacgtaagaagaag
aaaatgccagagatcttgaaaacggagctggatgagtgggctgcggccatgaatgccgag
tttgaagctgctgagcagtttgatctcctggttgaatga

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