Homo sapiens (human): 11214
Help
Entry
11214 CDS
T01001
Symbol
AKAP13, AKAP-13, AKAP-Lbc, ARHGEF13, BRX, HA-3, Ht31, LBC, PRKA13, PROTO-LB, PROTO-LBC, c-lbc, p47
Name
(RefSeq) A-kinase anchoring protein 13
KO
K16529
A-kinase anchor protein 13
Organism
hsa
Homo sapiens (human)
Pathway
hsa04928
Parathyroid hormone synthesis, secretion and action
hsa05163
Human cytomegalovirus infection
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
11214 (AKAP13)
09160 Human Diseases
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
11214 (AKAP13)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
11214 (AKAP13)
Membrane trafficking [BR:
hsa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
11214 (AKAP13)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PH_16
RhoGEF
PH
C1_1
RII_binding_1
C1_2
SOS1_NGEF_PH
Prok-RING_1
zf_RING-like
Ank_2
Motif
Other DBs
NCBI-GeneID:
11214
NCBI-ProteinID:
NP_009131
OMIM:
604686
HGNC:
371
Ensembl:
ENSG00000170776
UniProt:
Q12802
Structure
PDB
PDBj
LinkDB
All DBs
Position
15:85380603..85749358
Genome browser
AA seq
2813 aa
AA seq
DB search
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAP
GHDCCETVKVQLCASKEGLPVFVVAEEDFHFVQDEAYDAAQFLATSAGNQQALNFTRFLD
QSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYG
DCSVRHHRELDIYTLTSESDSHHEHPFPGDGCTGPIFKLMNIQQQLMKTNLKQMDSLMPL
MMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGN
RNEETGTKSSGMPTDQESLSSGDAVLQRDLVMEPGTAQYSSGGELGGISTTNVSTPDTAG
EMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDG
LEPYTLLAAGIGEAMSPSDLALLGLEEDVMPHQNSETNSSHAQSQKGKSSPICSTTGDDK
LCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVI
SDSTFSLANSPGSESVTKDDALSFVPSQKEKGTATPELHTATDYRDGPDGNSNEPDTRPL
EDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDT
QQFHEKSISADCAKDKALQLSNSPGASSAFLKAETEHNKEVAPQVSLLTQGGAAQSLVPP
GASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKA
VTDPQGVGTPEMIPLDWEKGKLEGADHSCTMGDAEEAQIDDEAHPVLLQPVAKELPTDME
LSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATG
SLAGCFAGREEPEKIILPVQGPEPAAEMPDVKAEDEVDFRASSISEEVAVGSIAATLKMK
QGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPN
RSRDRQSLDGFYSHGMGAEGRESESEPADPGDVEEEEMDSITEVPANCSVLRSSMRSLSP
FRRHSWGPGKNAASDAEMNHRSSMRVLGDVVRRPPIHRRSFSLEGLTGGAGVGNKPSSSL
EVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSA
ISSPLTKSISLMTISHPGLDNSRPFHSTFHNTSANLTESITEENYNFLPHSPSKKDSEWK
SGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSSIPVV
GPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPT
VIMRNKPSQPKERPRSAVLLVDETATTPIFANRRSQQSVSLSKSVSIQNITGVGNDENMS
NTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESWSRII
DSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFP
CLDELISIHSQFFQRILERKKESLVDKSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKF
CGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVLFQRI
LQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQ
MFAKEDLKRKKLVRDGSVFLKNAAGRLKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTV
ISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLNRDED
EGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPT
HSPRVLFRSNTEEALKGGPLMKSAINEVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVS
LPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKRNSEQ
VVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQ
RQDLANLQKQQAQYLEEKRRREREWEARERELREREALLAQREEEVQQGQQDLEKEREEL
QQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQVSHPHTKLMRIPSF
FPSPEEPPSPSAPSIAKSGSLDSELSVSPKRNSISRTHKDKGPFHILSSTSQTNKGPEGQ
SQAPASTSASTRLFGLTKPKEKKEKKKKNKTSRSQPGDGPASEVSAEGEEIFC
NT seq
8442 nt
NT seq
+upstream
nt +downstream
nt
atgaaacttaatccacagcaagctcccttatatggtgattgtgttgttacagtgctgctt
gctgaagaggacaaagctgaagatgatgtagtgttttacttggtatttttgggttccacc
ctccgtcactgtacaagtactcggaaggtcagttctgatacattggagaccattgctcct
ggtcatgattgttgtgaaacagtgaaggtgcagctctgtgcttccaaagagggccttccc
gtgtttgtggtggctgaagaagactttcatttcgtccaggatgaagcgtatgatgcagct
caattcctagcaaccagtgctggaaatcagcaggctttgaactttacccgttttcttgac
cagtcaggacccccatctggggatgtgaattcccttgataagaagttggtgctggcattc
aggcacctgaagctgcccacggagtggaatgtattggggacagatcagagtttgcatgat
gctggcccgcgagagacattgatgcattttgctgtgcggctgggactgctgaggttgacg
tggttcctgttgcagaagccaggtggccgcggagctctcagtatccacaaccaggaaggg
gcgacgcctgtgagcttggccttggagcgaggctatcacaagctgcaccagcttctaacc
gaggagaatgctggagaaccagactcctggagcagtttatcctatgaaataccgtatgga
gactgttctgtgaggcatcatcgagagttggacatctatacattaacctctgagtctgat
tcacatcatgaacacccatttcctggagacggttgcactggaccaatttttaaacttatg
aacatccaacagcaactaatgaaaacaaacctcaagcagatggacagtcttatgccctta
atgatgacagcacaggatccttccagtgccccagagacagatggccagtttcttccctgt
gcaccggagcccacggaccctcagcgactttcttcttctgaagagactgagagcactcag
tgctgcccagggagccctgttgcacagactgaaagtccctgtgatttgtcaagcatagtt
gaggaggagaatacagaccgttcctgtaggaagaaaaataaaggcgtggaaagaaaaggg
gaagaggtggagccagcacctattgtggactctggaactgtatctgatcaagacagctgc
cttcagagcttgcctgattgtggagtaaagggcacggaaggcctttcgtcctgtggaaac
agaaatgaagaaactggaacaaaatcttctggaatgcccacagaccaggagtccctgagc
agtggagatgctgtgcttcagagagacttggtcatggagccaggcacagcccagtattcc
tctggaggtgaactgggaggcatttcaacaacaaatgtcagtaccccagacactgcaggg
gaaatggaacatgggctcatgaacccagatgccactgtttggaagaatgtgcttcaggga
ggggaaagtacaaaggaaagatttgagaactctaatattggcacagctggagcctctgac
gtgcacgtcacaagtaagcctgtggataaaatcagtgttccaaactgtgcccctgctgcc
agttccctggatggtaacaaacctgctgagtcttcacttgcatttagtaatgaagaaacc
tccactgaaaaaacagcagaaacggaaacttcacgaagtcgtgaggagagtgctgatgct
ccagtagatcagaattctgtggtgattccagctgctgcaaaagacaagatttcagatgga
ttagaaccttatactctcttagcagcaggcataggtgaggcaatgtcaccctcagattta
gcccttcttgggctggaagaagatgtaatgccacaccagaactcagaaacaaattcatct
catgctcaaagccaaaagggcaaatcctcacccatttgttctacaactggagacgataaa
ctttgtgcagactctgcatgtcaacagaacacagtgacttctagtggcgatttggttgca
aaactgtgtgataacatagttagcgagtccgaaagcaccacagcaaggcaacccagctca
caagatccacccgatgcctcccactgtgaagacccacaggctcatacagtcacctctgac
cctgtaagggatacccaggaacgtgcggatttttgtcctttcaaagtggtggataacaaa
ggccaacgaaaagatgtgaaactagataaacctttaacaaatatgcttgaggtggtttca
catccacatccagttgtccctaaaatggagaaagaactggtgccagaccaggcagtaata
tcagacagtactttctctctggcaaacagtccaggcagtgaatcagtaaccaaggatgac
gcactttcttttgtcccctcccagaaagaaaagggaacagcaactcctgaactacataca
gctacagattatagagatggcccagatggaaattcgaatgagcctgatacgcggccacta
gaagacagggcagtaggcctgtccacatcctccactgctgcagagcttcagcacgggatg
gggaataccagtctcacaggacttggtggagagcatgagggtcccgcccctccagcaatc
ccagaagctctgaatatcaaggggaacactgactcttccctgcaaagtgtgggtaaggcc
actttggctttagattcagttttgactgaagaaggaaaacttctggtggtttcagaaagc
tctgcagctcaggaacaagataaggataaagcggtgacctgttcctctattaaggaaaat
gctctctcttcaggaactttgcaggaagagcagagaacaccacctcctggacaagatact
caacaatttcatgaaaaatcaatctcagctgactgtgccaaggacaaagcacttcagcta
agtaattcaccgggtgcatcctctgcctttcttaaggcagaaactgaacataacaaggaa
gtggccccacaagtctcactgctgactcaaggtggggctgcccagagcctggtgccacca
ggagcaagtctggccacagagtcaaggcaggaagccttgggggcagagcacaacagctcc
gctctgttgccatgtctgttgccagatgggtctgatgggtccgatgctcttaactgcagt
cagccttctcctctggatgttggagtgaagaacactcaatcccagggaaaaactagtgcc
tgtgaggtgagtggagatgtgacggtggatgttacaggggttaatgctctacaaggtatg
gctgagcccagaagagagaatatatcacacaacacccaagacatcctgattccaaacgtc
ttgttgagccaagagaagaatgccgttctaggtttgccagtggctctacaggacaaagct
gtgactgacccacagggagttggaaccccagagatgatacctcttgattgggagaaaggg
aagctggagggagcagaccacagctgtaccatgggtgacgctgaggaagcccaaatagac
gatgaagcacatcctgtcctactgcagcctgttgccaaggagctccccacagacatggag
ctctcagcccatgatgatggggccccagctggtgtgagggaagtcatgcgagccccgcct
tcaggcagggaaaggagcactccctctctaccttgcatggtctctgcccaggacgcacct
ctgcctaagggggcagacttgatagaggaggctgccagccgtatagtggatgctgtcatc
gaacaagtcaaggccgctggagcactgcttactgagggggaggcctgtcacatgtcactg
tccagccctgagttgggtcctctcactaaaggactagagagtgcttttacagaaaaagtg
agtactttcccacctggggagagcctaccaatgggcagtactcctgaggaagccacgggg
agccttgcaggatgttttgctggaagggaggagccagagaagatcattttacctgtccag
gggcctgagccagcagcagaaatgccagacgtgaaagctgaagatgaagtggattttaga
gcaagttcaatttctgaagaagtggctgtagggagcatagctgctacactgaagatgaag
caaggcccaatgacccaggcgataaaccgagaaaactggtgtacaatagagccatgccct
gatgcagcatctcttctggcttccaagcagagcccagaatgtgagaacttcctggatgtt
ggactgggcagagagtgtacctcaaaacaaggtgtacttaaaagagaatctgggagtgat
tctgacctctttcactcacccagtgatgacatggacagcatcatcttcccaaagccagag
gaagagcatttggcctgtgatatcaccggatccagttcatccaccgatgacacggcttca
ctggaccgacattcttctcatggcagtgatgtgtctctctcccagattttaaagccaaac
aggtcaagagatcggcaaagccttgatggattctacagccatgggatgggagctgagggt
cgagaaagtgagagtgagcctgctgacccaggcgacgtggaggaggaggagatggacagt
atcactgaagtgcctgcaaactgctctgtcctaaggagctccatgcgctctctttctccc
ttccggaggcacagctgggggcctgggaaaaatgcagccagcgatgcagaaatgaaccac
cggagttcaatgcgagttcttggggatgttgtcaggagacctcccattcataggagaagt
ttcagtctagaaggcttgacaggaggagctggtgtcggaaacaagccatcctcatctcta
gaagtaagctctgcaaatgccgaagagctcagacacccattcagtggtgaggaacgggtt
gactctttggtgtcactttcagaagaggatctggagtcagaccagagagaacataggatg
tttgatcagcagatatgtcacagatctaagcagcagggatttaattactgtacatcagcc
atttcctctccattgacaaaatccatctcattaatgacaatcagccatcctggattggac
aattcacggcccttccacagtaccttccacaataccagtgctaatctgactgagagtata
acagaagagaactataatttcctgccacatagcccctccaagaaagattctgaatggaag
agtggaacaaaagtcagtcgtacattcagctacatcaagaataaaatgtctagcagcaag
aagagcaaagaaaaggaaaaagaaaaagataagattaaggagaaggagaaagattctaaa
gacaaggagaaagataagaagactgtcaacgggcacactttcagttccattcctgttgtg
ggtcccatcagctgtagccagtgtatgaagcccttcaccaacaaagatgcctatacttgt
gcaaattgcagtgcttttgtccacaaaggctgccgagaaagtctagcctcctgtgcaaag
gtcaaaatgaagcagcccaaagggagccttcaggcacatgacacatcatcactgcccacg
gtcattatgagaaacaagccctcacagcccaaggagcgtcctcggtccgcagtcctcctg
gtggatgaaaccgctaccaccccaatatttgccaatagacgatcccagcagagtgtctcg
ctctccaaaagtgtctccatacagaacattactggagttggcaatgatgagaacatgtca
aacacctggaaattcctgtctcattcaacagactcactaaataaaatcagcaaggtcaat
gagtcaacagaatcacttactgatgagggagtaggtacagacatgaatgaaggacaacta
ctgggagactttgagattgagtccaaacagctggaagcagagtcttggagtcggataata
gacagcaagtttctaaaacagcaaaagaaagatgtggtcaaacggcaagaagtaatatat
gagttgatgcagacagagtttcatcatgtccgcactctcaagatcatgagtggtgtgtac
agccaggggatgatggcggatctgctttttgagcagcagatggtagaaaagctgttcccc
tgtttggatgagctgatcagtatccatagccaattcttccagaggattctggagcggaag
aaggagtctctggtggataaaagtgaaaagaactttctcatcaagaggataggggatgtg
cttgtaaatcagttttcaggtgagaatgcagaacgtttaaagaagacatatggcaagttt
tgtgggcaacataaccagtctgtaaactacttcaaagacctttatgccaaggataagcgt
tttcaagcctttgtaaagaagaagatgagcagttcagttgttagaaggcttggaattcca
gagtgcatattgcttgtaactcagcggattaccaagtacccagttttattccaaagaata
ttgcagtgtaccaaagacaatgaagtggagcaggaagatctagcacagtccttgagcctg
gtgaaggatgtgattggagctgtagacagcaaagtggcaagttatgaaaagaaagtgcgt
ctcaatgagatttatacaaagacagatagcaagtcaatcatgaggatgaagagtggtcag
atgtttgccaaggaagatttgaaacggaagaagcttgtacgtgatgggagtgtgtttctg
aagaatgcagcaggaaggttgaaagaggttcaagcagttcttctcactgacattttagtt
ttccttcaagaaaaagaccagaagtacatctttgcatcattggaccagaagtcaacagtg
atctctttaaagaagctgattgtgagagaagtggcacatgaggagaaaggtttattcctg
atcagcatggggatgacagatccagagatggtagaagtccatgccagctccaaagaggaa
cgaaacagctggattcagatcattcaggacacaatcaacaccctgaacagagatgaagat
gaaggaattcctagtgagaatgaggaagaaaagaaaatgttggacaccagagcccgagaa
ttaaaagaacaacttcaccagaaggaccaaaaaatcctactcttgttggaagagaaggag
atgattttccgggacatggctgagtgcagcacccctctcccagaggattgctccccaaca
catagccctagagttctcttccgctccaacacagaagaggctctcaaaggaggaccttta
atgaaaagtgcaataaatgaggtggagatccttcagggtttggtgagtggaaatctggga
ggcacacttgggccgactgtcagcagccccattgagcaagatgtggtcggtcccgtttcc
ctgccccggagagcagagacctttggaggatttgacagccatcagatgaatgcttcaaaa
ggaggcgagaaggaagagggagatgatggccaagatcttaggagaacggaatcagatagt
ggcctaaaaaagggtggaaatgctaacctggtatttatgcttaaaagaaacagtgagcag
gttgtccagagcgttgttcatctctacgagctcctcagcgctctgcagggtgtggtgctg
cagcaggacagctacattgaggaccagaaactggtgctgagcgagagggcgctcactcgc
agcttgtcccgcccgagctccctcattgagcaggagaagcagcgcagcctggagaagcag
cgccaggacctggccaacctgcagaagcagcaggcccagtacctcgaggagaagcgcagg
cgcgagcgtgagtgggaagctcgtgagagggagctgcgggagcgggaggccctcctggcc
cagcgcgaggaggaggtgcagcaggggcagcaggacctggaaaaggagcgggaggagctc
cagcagaagaagggcacataccagtatgacctggagcgactgcgtgctgcccagaaacag
cttgagagggaacaggagcagctgcgccgggaggcagagcggctcagccagcggcagaca
gaacgggacctgtgtcaggtttcccatccacataccaagctgatgaggatcccatcgttc
ttccccagtcctgaggagcccccctcgccatctgcaccttccatagccaaatcagggtca
ttggactcagaactttcagtgtccccaaaaaggaacagcatctctcggacacacaaagat
aaggggccttttcacatactgagttcaaccagccagacaaacaaaggaccagaagggcag
agccaggcccctgcgtccacctctgcctctacccgcctgtttgggttaacaaagccaaag
gaaaagaaggagaaaaaaaagaagaacaaaaccagccgctctcagcccggtgatggtccc
gcgtcagaagtatcagcagagggtgaagagatcttctgctga
Homo sapiens (human): 9138
Help
Entry
9138 CDS
T01001
Symbol
ARHGEF1, GEF1, IMD62, LBCL2, LSC, P115-RHOGEF, SUB1.5
Name
(RefSeq) Rho guanine nucleotide exchange factor 1
KO
K12330
Rho guanine nucleotide exchange factor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04270
Vascular smooth muscle contraction
hsa04611
Platelet activation
hsa04810
Regulation of actin cytoskeleton
hsa04928
Parathyroid hormone synthesis, secretion and action
hsa05130
Pathogenic Escherichia coli infection
hsa05135
Yersinia infection
hsa05163
Human cytomegalovirus infection
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05417
Lipid and atherosclerosis
Network
nt06167
Human cytomegalovirus (HCMV)
nt06180
Pathogenic Escherichia coli
nt06533
Chemokine signaling
Element
N00405
CXCR4-GNA12/13-Rho signaling pathway
N01088
Escherichia EspH to LPA-GNA12/13-RhoA signaling pathway
N01097
LPA-GNA12/13-RhoA signaling pathway
N01768
CXCR4-GNA12/13 signaling pathway
Disease
H02526
Disorders of adaptive immunity
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
9138 (ARHGEF1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
9138 (ARHGEF1)
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
9138 (ARHGEF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
9138 (ARHGEF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
9138 (ARHGEF1)
05205 Proteoglycans in cancer
9138 (ARHGEF1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
9138 (ARHGEF1)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
9138 (ARHGEF1)
05135 Yersinia infection
9138 (ARHGEF1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
9138 (ARHGEF1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
9138 (ARHGEF1)
Membrane trafficking [BR:
hsa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
9138 (ARHGEF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PH_13
AbiJ_NTD3
SOS1_NGEF_PH
Motif
Other DBs
NCBI-GeneID:
9138
NCBI-ProteinID:
NP_004697
OMIM:
601855
HGNC:
681
Ensembl:
ENSG00000076928
UniProt:
Q92888
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:41883184..41930141
Genome browser
AA seq
912 aa
AA seq
DB search
MEDFARGAASPGPSRPGLVPVSIIGAEDEDFENELETNSEEQNSQFQSLEQVKRRPAHLM
ALLQHVALQFEPGPLLCCLHADMLGSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPNVAF
ELDRTRADLISEDVQRRFVQEVVQSQQVAVGRQLEDFRSKRLMGMTPWEQELAQLEAWVG
RDRASYEARERHVAERLLMHLEEMQHTISTDEEKSAAVVNAIGLYMRHLGVRTKSGDKKS
GRNFFRKKVMGNRRSDEPAKTKKGLSSILDAARWNRGEPQVPDFRHLKAEVDAEKPGATD
RKGGVGMPSRDRNIGAPGQDTPGVSLHPLSLDSPDREPGADAPLELGDSSPQGPMSLESL
APPESTDEGAETESPEPGDEGEPGRSGLELEPEEPPGWRELVPPDTLHSLPKSQVKRQEV
ISELLVTEAAHVRMLRVLHDLFFQPMAECLFFPLEELQNIFPSLDELIEVHSLFLDRLMK
RRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKDPRFCAFV
QEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPTEREKVELAAECCREILH
HVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTK
DKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVAT
DHKAFYVLFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPAPASRPKPRPSPSST
REPLLSSSENGNGGRETSPADARTERILSDLLPFCRPGPEGQLAATALRKVLSLKQLLFP
AEEDNGAGPPRDGDGVPGGGPLSPARTQEIQENLLSLEETMKQLEELEEEFCRLRPLLSQ
LGGNSVPQPGCT
NT seq
2739 nt
NT seq
+upstream
nt +downstream
nt
atggaagacttcgcccgaggggcggcctccccaggcccctcccggcctggcctggttccc
gtcagcatcatcggggctgaggatgaggattttgagaacgagctggagacaaactcagaa
gagcaaaacagccagttccagagcctggagcaggtgaagcggcgcccagcccacctcatg
gccctcctgcagcacgtggccctgcagtttgagccaggacccctgctttgctgtctgcat
gccgacatgctgggctcactgggccccaaggaggccaagaaggccttcctggacttctac
cacagcttcctggagaagacagcggttctccgggtgccggtccctcccaacgtcgccttt
gaacttgaccgcactagggctgacctcatctccgaggatgtccagcggcggttcgtgcag
gaggtggtgcaaagccagcaggtagccgtgggccggcagctggaggacttccgttccaag
cggctcatgggcatgacgccctgggagcaggagctggcccagctggaggcttgggttggg
cgggaccgagccagctacgaggcccgggagcggcacgtggcggagcggctgctcatgcac
ctggaggagatgcaacataccatctctaccgacgaagaaaagagtgctgccgtggtcaac
gccattggcctgtacatgcgccaccttggggtgcggaccaagagtggagacaagaagtcg
gggaggaacttcttccggaaaaaggtgatggggaaccggcggtcggacgagcctgccaag
accaagaaggggctgagcagcatcctggatgccgcccgctggaaccggggagagccccag
gttccagattttcgacacctcaaagcagaggttgatgccgagaagccaggtgctacagac
cggaagggaggcgtggggatgccctctcgggaccggaatatcggggctcctgggcaggac
acccctggagtctctctgcaccctctgtccctggacagcccagaccgggaaccaggtgct
gacgcccccctggagctgggggactcatccccgcagggcccaatgagcctggagtccttg
gcgcccccagagagtaccgacgagggggccgaaaccgagagccccgagcctggagatgag
ggggagccggggcggtcgggactggagcttgaaccagaagagcctcccggctggcgggaa
ctcgtccccccagacaccctgcacagcctgcccaagagccaggtgaagcggcaggaggtc
atcagcgagctgctggtgacagaggcggcccacgtgcgcatgctgcgggtgctgcacgac
ctcttcttccagcccatggcagaatgcctgttcttccccttggaggagctgcagaacatc
ttccccagcctggacgagctcatcgaggtgcattccctgttcctcgatcgcctgatgaag
cggaggcaggagagtggctacctcatcgaggagatcggagacgtgctgctggcccggttt
gatggtgctgagggctcctggttccagaaaatctcctcccgcttctgcagccgccagtca
tttgccttagagcagctcaaagccaagcaacgcaaggaccctcggttctgtgccttcgtg
caggaagctgagagccgcccgcggtgccgccgcctgcagctgaaggacatgatccccacg
gagatgcagcggctgaccaagtaccccctgctcctgcagagcatcgggcagaacacagaa
gagcccacagaacgggagaaagtggagctggcagccgagtgctgccgggaaattctacac
cacgtcaaccaagccgtgcgtgacatggaggacctgctgaggctcaaggactatcagcgg
cgcctggacttgtcccaccttcggcagagcagcgaccctatgctgagcgagttcaagaac
ctggacatcaccaagaagaaattggtccacgagggcccactgacgtggcgggtgactaag
gacaaggcagtggaggtgcatgtgctgctgctggacgacctgctgctgctgctccagcgc
caggacgagcggctgctgctcaagtcccatagccggacactgacgcccacgcccgatggc
aagaccatgctgcggcccgtgctgcggctcacctccgccatgacccgcgaggtggccacc
gatcacaaagccttctacgtcctttttacctgggaccaggaggcccagatatacgagctg
gtggcacagactgtgtcggagcggaaaaactggtgtgctctcatcactgagactgccgga
tccctgaaagtccctgcccctgcctctcgccctaagccccggcccagcccgagcagcacc
cgagaacccctcctcagcagctctgagaacggcaatggtggccgagagacgtctccagct
gatgcccggaccgagagaatcctcagtgacctcctgcccttctgcagaccaggccccgag
ggccagctcgctgccacggcccttcggaaagtgctgtccctgaagcagcttctgtttccg
gcggaggaagacaatggggcggggcctcctcgagatggggatggggtcccagggggcggc
cccctgagcccagcacggacccaggaaatccaggagaacctgctcagcttggaggagacc
atgaagcagctggaggagttggaggaggaattttgccgcctgagacccctcctgtctcag
cttggggggaactctgtcccccagcctggctgcacttga
Homo sapiens (human): 9826
Help
Entry
9826 CDS
T01001
Symbol
ARHGEF11, GTRAP48, PDZ-RHOGEF
Name
(RefSeq) Rho guanine nucleotide exchange factor 11
KO
K12331
Rho guanine nucleotide exchange factor 11
Organism
hsa
Homo sapiens (human)
Pathway
hsa04270
Vascular smooth muscle contraction
hsa04928
Parathyroid hormone synthesis, secretion and action
hsa05130
Pathogenic Escherichia coli infection
hsa05163
Human cytomegalovirus infection
hsa05200
Pathways in cancer
Network
nt06180
Pathogenic Escherichia coli
Element
N01097
LPA-GNA12/13-RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
9826 (ARHGEF11)
09153 Circulatory system
04270 Vascular smooth muscle contraction
9826 (ARHGEF11)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
9826 (ARHGEF11)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
9826 (ARHGEF11)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
9826 (ARHGEF11)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
9826 (ARHGEF11)
Membrane trafficking [BR:
hsa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
9826 (ARHGEF11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
RGS
PDZ_2
PH_13
PH
DUF1410
Pept_S41_N_bact
Motif
Other DBs
NCBI-GeneID:
9826
NCBI-ProteinID:
NP_055599
OMIM:
605708
HGNC:
14580
Ensembl:
ENSG00000132694
UniProt:
O15085
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:complement(156934840..157046903)
Genome browser
AA seq
1522 aa
AA seq
DB search
MSVRLPQSIDRLSSLSSLGDSAPERKSPSHHRQPSDASETTGLVQRCVIIQKDQHGFGFT
VSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLL
GSSPSSMGISGLQQDPSPAGAPRITSVIPSPPPPPPLPPPQRITGPKPLQDPEVQKHATQ
ILRNMLRQEEKELQDILPLYGDTSQRPSEGRLSLDSQEGDSGLDSGTERFPSLSESLMNR
NSVLSDPGLDSPRTSPVIMARVAQHHRRQGSDAAVPSTGDQGVDQSPKPLIIGPEEDYDP
GYFNNESDIIFQDLEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQASPKDSRSL
GKDIWNIFLEKNAPLRVKIPEMLQAEIDSRLRNSEDARGVLCEAQEAAMPEIQEQIHDYR
TKRTLGLGSLYGENDLLDLDGDPLRERQVAEKQLAALGDILSKYEEDRSAPMDFALNTYM
SHAGIRLREARPSNTAEKAQSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKKRNPILKYI
GKPKSSSQSTFHIPLSPVEVKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLES
DSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEATRLHQSASSSTSSLS
TRSLENPTPPFTPKMGRRSIESPSLGFCTDTLLPHLLEDDLGQLSDLEPEPDAQNWQHTV
GKDVVAGLTQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKENLMPREELARLFP
NLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIAL
ELIKTKQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGT
SEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLDATALERASNPLAAEFKSLD
LTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQ
TFSPVLKLNAVLIRSVATDKRAFFIICTSKLGPPQIYELVALTSSDKNTWMELLEEAVRN
ATRHPGAAPMPVHPPPPGPREPAQQGPTPSRVELDDSDVFHGEPEPEELPGGTGSQQRVQ
GKHQVLLEDPEQEGSAEEEELGVLPCPSTSLDGENRGIRTRNPIHLAFPGPLFMEGLADS
ALEDVENLRHLILWSLLPGHTMETQAAQEPEDDLTPTPSVISVTSHPWDPGSPGQAPPGG
EGDNTQLAGLEGERPEQEDMGLCSLEHLPPRTRNSGIWESPELDRNLAEDASSTEAAGGY
KVVRKAEVAGSKVVPALPESGQSEPGPPEVEGGTKATGNCFYVSMPSGPPDSSTDHSEAP
MSPPQPDSLPAGQTEPQPQLQGGNDDPRRPSRSPPSLALRDVGMIFHTIEQLTLKLNRLK
DMELAHRELLKSLGGESSGGTTPVGSFHTEAARWTDGSLSPPAKEPLASDSRNSHELGPC
PEDGSDAPLEDSTADAAASPGP
NT seq
4569 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtaaggttaccccagagtatagacaggttaagtagcctgtcttctctgggagat
tctgcaccagagcgcaagtccccttcccaccatcgccagccttcggatgcctctgagaca
acaggtctcgttcaacgctgtgtcattatccaaaaggaccagcatggcttcggcttcaca
gtcagtggggatcgcattgttctggtgcagtctgtgcggcctggaggtgcagccatgaag
gccggtgtgaaagagggcgaccggatcatcaaagtcaacggcaccatggtgaccaatagc
tcacacctggaagtggtaaagctgatcaaatctggcgcctatgtcgcactcaccctcctg
ggctcttcaccttcatccatgggcatctctgggctccagcaggacccatccccagcagga
gctccccgaatcacgtcagtgatcccctcaccaccacctcctccacctctaccacctcca
caacgcatcacaggacccaaacctctgcaggatcccgaagttcaaaaacatgccacccag
atcctcaggaatatgctgaggcaggaagaaaaagaattacaggacatacttccactatat
ggtgacaccagccagagaccatcagaaggccggctctctctggattcccaggagggggac
agtggcttggactctgggacagaacgctttccttccctcagtgagtcattgatgaatcgg
aactcggtactgtcagaccctgggctagacagtcctcgaacctcccctgtgatcatggcc
agggtggcccagcaccacaggcggcagggctcggatgcagcagtcccctcaaccggtgac
cagggtgtagatcaaagcccaaagcctttaattattggcccagaggaagactatgacccg
ggttatttcaacaacgagagcgacatcatattccaggatctggagaaactgaagtctcgg
ccagctcacctgggggtttttctacgttacatcttctctcaggcggaccccagtccactg
cttttttacctgtgtgcagaagtttatcagcaggcaagccccaaggattcccgaagcttg
gggaaagacatctggaatattttcctggagaaaaatgcgcctctgagagtgaagatccct
gagatgctacaggctgaaattgactcgcgcctgcggaacagcgaagatgcccgtggtgtt
ctctgtgaagctcaagaggcagccatgcctgagatccaagagcagatccacgactacaga
acgaagcgcacactggggctgggcagcctgtatggtgaaaatgacctgctggacctggat
ggggaccctctccgagagcgccaagtggctgagaagcagctggctgcccttggagatatt
ttgtccaagtatgaggaagacaggagcgcccccatggacttcgccctcaatacctacatg
agccatgctgggatccgtcttcgagaggcacgaccttccaacacagctgaaaaggcccag
tctgctcctgacaaggacaagtggctaccgttcttccctaagaccaagaagagcagcaat
tccaagaaagaaaaggatgccttggaggacaagaagcgaaaccctatcctcaaatacatt
gggaagcccaaaagctcttctcaaagcacatttcatattcccttgtcccctgtggaagtc
aaaccaggcaatgtgaggaacatcattcagcactttgagaacaaccagcagtatgatgcc
ccagaacctgggacacaacgactctcgaccggaagctttcctgaggacctgctggagagt
gacagttcacgctcagagattcgcctgggccgctctgaaagcctcaagggccgggaagag
atgaaacggtctcgaaaggcagagaacgtgccccgctctcgcagtgatgttgacatggat
gctgctgcggaggctactcgcctgcaccagtcagcctcgtcctctacctccagcctctcc
accaggtctcttgagaacccaacccctccattcactcccaaaatgggccgcaggagcatt
gagtcccccagtttggggttctgcacagataccctccttccccacctcctagaggatgat
ctgggccagctgtctgacctggagccagagccagatgcccaaaattggcagcatacagtg
ggcaaggatgtggtggctgggctaacccagcgggagattgaccggcaagaggtcatcaat
gagctgtttgtgactgaagcttcccacctgcgcacactccgggtcctggacctgatcttc
taccagcgaatgaagaaggagaacctgatgccccgggaggagctggcccggctcttcccg
aacctgcctgaactcatagagattcacaattcctggtgtgaagccatgaagaagctccgg
gaggaaggccccatcatcaaagagatcagtgacctcatgctggcccggtttgatggccct
gcccgagaggaactccagcaagtggctgcacagttctgttcctatcagtcaatagcccta
gagctaatcaagaccaagcaacgcaaggagagtcgattccagctcttcatgcaggaggct
gagagccaccctcagtgtcggcggctgcagctgagagacctcatcatctctgagatgcag
cggctcaccaagtacccgctgctgctggagagcatcatcaagcacacagagggtggcacc
tctgagcatgagaagctgtgccgggcccgggaccagtgccgggagattctcaagtatgtg
aatgaagcggtaaaacaaacagagaaccgccaccgtttagagggctaccagaaacgcctg
gatgccaccgccctggagagggccagcaaccccctggcagcagagttcaagagcctggat
cttacaaccagaaaaatgatccatgagggacccctgacctggaggatcagcaaggataag
accttggacctccacgtgctgctgctggaggacctcctagtgctgctacagaaacaggat
gagaagctattgctgaagtgccacagcaagactgctgtgggctcctcagacagcaagcag
accttcagccccgtgctcaagctcaatgctgtgctcatccgctctgtggccacagataaa
cgggccttcttcatcatctgcacctccaagctgggcccaccccagatctatgagctggtt
gcattgacgtcatcagacaagaacacatggatggagctcttagaagaggccgtgcggaat
gccaccaggcaccccggagctgccccaatgcccgtccatcctccacccccaggtccccgg
gagccagcccagcagggccccacacccagcagggtagaactggatgactcagacgtgttc
catggtgaacctgaacctgaggagctgcctggaggcactgggtcccagcagagggtccaa
gggaagcaccaggtcctgctagaggaccctgagcaggagggcagtgcagaggaagaggaa
ctgggtgtcctgccttgcccttccacatccctggatggagagaacaggggcatcaggaca
aggaaccccatccacttggccttcccaggccctctgttcatggaagggctcgctgactcc
gctctggaagatgtggagaacctgcgacatctgatcctgtggagcctgctgccaggtcac
accatggaaactcaggctgcccaggagcccgaggacgacctgacacccacaccttctgtc
atcagcgtcacctctcacccctgggacccaggctccccagggcaagcaccccctgggggt
gaaggggacaacacccagcttgcagggctggagggggaacggccagagcaggaagacatg
ggtctctgttctctggaacacctacccccaaggaccagaaattctgggatatgggagtct
ccagaactggacaggaatctggctgaagatgcttcaagcacagaggcagcaggaggttac
aaagttgtgagaaaagctgaggtggcaggcagcaaggttgtccctgcactaccagagagt
ggccagtcagagcctgggccacctgaagtggaaggcggaacaaaggctacggggaactgc
ttttatgtcagcatgccatcaggacccccggactcaagcaccgaccactcagaggcaccc
atgagcccccctcagcctgacagcctccctgcagggcagacagagcctcagcctcagctg
cagggaggcaacgatgatccaagacgccccagccgctctcctccaagcctggccctcagg
gacgtgggcatgatcttccataccattgagcagctcactctcaagctcaacaggctcaag
gatatggagctggcccacagagagctgctcaagtcccttgggggagagtcatctggtggc
accacgcctgtgggcagtttccacacagaagcagctagatggacagatggctccctctca
cctcccgctaaggagcccctagcttctgactccaggaacagccatgaactggggccctgc
cctgaggatggctctgacgcccccctggaagacagcacagcagacgcagccgcgtcacca
ggaccataa
DBGET
integrated database retrieval system
