KEGG T01001: 1329

Homo sapiens (human): 1329

Entry

1329              CDS       T01001

Symbol

COX5B, COXVB

Name

(RefSeq) cytochrome c oxidase subunit 5B

K02265

cytochrome c oxidase subunit 5b

Organism

hsa Homo sapiens (human)

Pathway

hsa00190

Oxidative phosphorylation

hsa01100

Metabolic pathways

hsa04260

Cardiac muscle contraction

hsa04714

Thermogenesis

hsa04932

Non-alcoholic fatty liver disease

hsa05010

Alzheimer disease

hsa05012

Parkinson disease

hsa05014

Amyotrophic lateral sclerosis

hsa05016

Huntington disease

hsa05020

Prion disease

hsa05022

Pathways of neurodegeneration - multiple diseases

hsa05208

Chemical carcinogenesis - reactive oxygen species

hsa05415

Diabetic cardiomyopathy

Module

hsa_M00154

Cytochrome c oxidase

Network

nt06252  Mitochondrial ROS formation (cancer)
nt06460  Alzheimer disease
nt06466  Pathways of neurodegeneration

Element

N00998

Electron transfer in Complex IV

N00999

Mutation-caused aberrant Abeta to electron transfer in Complex IV

N01394

Arsenic to electron transfer in complex IV

Brite

KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    1329 (COX5B)
09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    1329 (COX5B)
  09159 Environmental adaptation
   04714 Thermogenesis
    1329 (COX5B)
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    1329 (COX5B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    1329 (COX5B)
   05012 Parkinson disease
    1329 (COX5B)
   05014 Amyotrophic lateral sclerosis
    1329 (COX5B)
   05016 Huntington disease
    1329 (COX5B)
   05020 Prion disease
    1329 (COX5B)
   05022 Pathways of neurodegeneration - multiple diseases
    1329 (COX5B)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    1329 (COX5B)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    1329 (COX5B)

SSDB

Motif

Pfam:

COX5B

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Pharos:

P10606(Tbio)

UniProt:

P10606 A0A384NL93

Structure

LinkDB

Position

2:97646062..97648383

AA seq 129 aa
MASRLLRGAGTLAAQALRARGPSGAAAMRSMASGGGVPTDEEQATGLEREIMLAAKKGLD
PYNVLAPKGASGTREDPNLVPSISNKRIVGCICEEDNTSVVWFWLHKGEAQRCPRCGAHY
KLVPQQLAH

NT seq 390 nt +upstreamnt +downstreamnt
atggcttcaaggttacttcgcggagctggaacgctggccgcgcaggccctgagggctcgc
ggccccagtggcgcggccgcgatgcgctccatggcatctggaggtggtgttcccactgat
gaagagcaggcgactgggttggagagggagatcatgctggctgcaaagaagggactggac
ccatacaatgtactggccccaaagggagcttcaggcaccagggaagaccctaatttagtc
ccctccatctccaacaagagaatagtaggctgcatctgtgaagaggacaataccagcgtc
gtctggttttggctgcacaaaggcgaggcccagcgatgcccccgctgtggagcccattac
aagctggtgccccagcagctggcacactga

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