Homo sapiens (human): 29851 Help Entry 29851             CDS       T01001                                  Gene name ICOS, AILIM, CD278, CVID1 Definition (RefSeq) inducible T cell costimulator   KO K06713   inducible T-cell co-stimulator Organism hsa  Homo sapiens (human) Pathway hsa04514   Cell adhesion molecules hsa04660   T cell receptor signaling pathway hsa04672   Intestinal immune network for IgA production hsa05340   Primary immunodeficiency Disease H00088   Common variable immunodeficiency Drug target Feladilimab:  D11996 Vopratelimab:  D11433 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04514 Cell adhesion molecules     29851 (ICOS)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     29851 (ICOS)    04672 Intestinal immune network for IgA production     29851 (ICOS)  09160 Human Diseases   09163 Immune disease    05340 Primary immunodeficiency     29851 (ICOS)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:hsa04090]     29851 (ICOS) CD molecules [BR:hsa04090]  Proteins   29851 (ICOS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  V-set_2 V-set Motif Other DBs NCBI-GeneID:  29851 NCBI-ProteinID:  NP_036224 OMIM:  604558 HGNC:  5351 Ensembl:  ENSG00000163600 Vega:  OTTHUMG00000132880 Pharos:  Q9Y6W8(Tbio) UniProt:  Q9Y6W8 Q53QY6 LinkDB All DBs Position 2q33.2 AA seq 199 aa AA seqDB search MKSGLWYFFLFCLRIKVLTGEINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQ ILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFK VTLTGGYLHIYESQLCCQLKFWLPIGCAAFVVVCILGCILICWLTKKKYSSSVHDPNGEY MFMRAVNTAKKSRLTDVTL NT seq 600 nt NT seq  +upstreamnt  +downstreamnt atgaagtcaggcctctggtatttctttctcttctgcttgcgcattaaagttttaacagga gaaatcaatggttctgccaattatgagatgtttatatttcacaacggaggtgtacaaatt ttatgcaaatatcctgacattgtccagcaatttaaaatgcagttgctgaaaggggggcaa atactctgcgatctcactaagacaaaaggaagtggaaacacagtgtccattaagagtctg aaattctgccattctcagttatccaacaacagtgtctctttttttctatacaacttggac cattctcatgccaactattacttctgcaacctatcaatttttgatcctcctccttttaaa gtaactcttacaggaggatatttgcatatttatgaatcacaactttgttgccagctgaag ttctggttacccataggatgtgcagcctttgttgtagtctgcattttgggatgcatactt atttgttggcttacaaaaaagaagtattcatccagtgtgcacgaccctaacggtgaatac atgttcatgagagcagtgaacacagccaaaaaatctagactcacagatgtgaccctataa

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