Homo sapiens (human): 29851 Help Entry 29851             CDS       T01001                                  Symbol ICOS, AILIM, CD278, CVID1 Name (RefSeq) inducible T cell costimulator   KO K06713   inducible T-cell co-stimulator Organism hsa  Homo sapiens (human) Pathway hsa04514   Cell adhesion molecules hsa04660   T cell receptor signaling pathway hsa04672   Intestinal immune network for IgA production hsa05340   Primary immunodeficiency Network nt06537  TCR/BCR signaling   Element N01696   ICOSLG/ICOS-PI3K signaling pathway Disease H00088   Common variable immunodeficiency Drug target Acazicolcept:  D12300 Feladilimab:  D11996 Izuralimab:  D12195 Vopratelimab:  D11433 Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     29851 (ICOS)  09160 Human Diseases   09163 Immune disease    05340 Primary immunodeficiency     29851 (ICOS)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:hsa04090]     29851 (ICOS) CD molecules [BR:hsa04090]  Proteins   29851 (ICOS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  V-set_2 V-set Motif Other DBs NCBI-GeneID:  29851 NCBI-ProteinID:  NP_036224 OMIM:  604558 HGNC:  5351 Ensembl:  ENSG00000163600 UniProt:  Q9Y6W8 Q53QY6 Structure PDBPDBj LinkDB All DBs Position 2:203936763..203961577 Genome browser AA seq 199 aa AA seqDB search MKSGLWYFFLFCLRIKVLTGEINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQ ILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFK VTLTGGYLHIYESQLCCQLKFWLPIGCAAFVVVCILGCILICWLTKKKYSSSVHDPNGEY MFMRAVNTAKKSRLTDVTL NT seq 600 nt NT seq  +upstreamnt  +downstreamnt atgaagtcaggcctctggtatttctttctcttctgcttgcgcattaaagttttaacagga gaaatcaatggttctgccaattatgagatgtttatatttcacaacggaggtgtacaaatt ttatgcaaatatcctgacattgtccagcaatttaaaatgcagttgctgaaaggggggcaa atactctgcgatctcactaagacaaaaggaagtggaaacacagtgtccattaagagtctg aaattctgccattctcagttatccaacaacagtgtctctttttttctatacaacttggac cattctcatgccaactattacttctgcaacctatcaatttttgatcctcctccttttaaa gtaactcttacaggaggatatttgcatatttatgaatcacaactttgttgccagctgaag ttctggttacccataggatgtgcagcctttgttgtagtctgcattttgggatgcatactt atttgttggcttacaaaaaagaagtattcatccagtgtgcacgaccctaacggtgaatac atgttcatgagagcagtgaacacagccaaaaaatctagactcacagatgtgaccctataa

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