Homo sapiens (human): 3280
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Entry
3280 CDS
T01001
Symbol
HES1, HES-1, HHL, HRY, bHLHb39
Name
(RefSeq) hes family bHLH transcription factor 1
KO
K06054
hairy and enhancer of split 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa03460
Fanconi anemia pathway
hsa04330
Notch signaling pathway
hsa04950
Maturity onset diabetes of the young
hsa05165
Human papillomavirus infection
hsa05169
Epstein-Barr virus infection
hsa05200
Pathways in cancer
hsa05224
Breast cancer
Network
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06216
NOTCH signaling (cancer)
nt06270
Breast cancer
nt06465
Prion disease
nt06511
NOTCH signaling
Element
N00086
Notch signaling pathway
N00087
NOTCH-overexpression to Notch signaling pathway
N00225
EBV EBNA2 to RBP-Jk-mediated transcription
N00380
HPV E6 to Notch signaling pathway
N00381
HPV E6 to Notch signaling pathway
N00382
HPV E6 to Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03460 Fanconi anemia pathway
3280 (HES1)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
3280 (HES1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
3280 (HES1)
09162 Cancer: specific types
05224 Breast cancer
3280 (HES1)
09172 Infectious disease: viral
05169 Epstein-Barr virus infection
3280 (HES1)
05165 Human papillomavirus infection
3280 (HES1)
09167 Endocrine and metabolic disease
04950 Maturity onset diabetes of the young
3280 (HES1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
3280 (HES1)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
3280 (HES1)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Hairy, Hairy/E(SPL)
3280 (HES1)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
DSBR (double strand breaks repair)
FA (Fanconi anemia) pathway
FA core complex binding factors
3280 (HES1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Hairy_orange
HLH
bHLH_NCOA
Spectrin_1st_PEPL
ALTTAQ_rpt
Motif
Other DBs
NCBI-GeneID:
3280
NCBI-ProteinID:
NP_005515
OMIM:
139605
HGNC:
5192
Ensembl:
ENSG00000114315
UniProt:
Q14469
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:194136148..194138732
Genome browser
AA seq
280 aa
AA seq
DB search
MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTL
ILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNE
VTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHPALQAPPPPPPGPGGPQHAP
FAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAH
SGPVIPVYTSNSGTSVGPNAVSPSSGPSLTADSMWRPWRN
NT seq
843 nt
NT seq
+upstream
nt +downstream
nt
atgccagctgatataatggagaaaaattcctcgtccccggtggctgctaccccagccagt
gtcaacacgacaccggataaaccaaagacagcatctgagcacagaaagtcatcaaagcct
attatggagaaaagacgaagagcaagaataaatgaaagtctgagccagctgaaaacactg
attttggatgctctgaagaaagatagctcgcggcattccaagctggagaaggcggacatt
ctggaaatgacagtgaagcacctccggaacctgcagcgggcgcagatgacggctgcgctg
agcacagacccaagtgtgctggggaagtaccgagccggcttcagcgagtgcatgaacgag
gtgacccgcttcctgtccacgtgcgagggcgttaataccgaggtgcgcactcggctgctc
ggccacctggccaactgcatgacccagatcaatgccatgacctaccccgggcagccgcac
cccgccttgcaggcgccgccaccgcccccaccgggacccggcggcccccagcacgcgccg
ttcgcgccgccgccgccactcgtgcccatccccgggggcgcggcgccccctcccggcggc
gccccctgcaagctgggcagccaggctggagaggcggctaaggtgtttggaggcttccag
gtggtaccggctcccgatggccagtttgctttcctcattcccaacggggccttcgcgcac
agcggccctgtcatccccgtctacaccagcaacagcggcacctccgtgggccccaacgca
gtgtcaccttccagcggcccctcgcttacggcggactccatgtggaggccgtggcggaac
tga
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