KEGG   Homo sapiens (human): 4659
Entry
4659              CDS       T01001                                 
Symbol
PPP1R12A, GUBS, M130, MBS, MYPT1
Name
(RefSeq) protein phosphatase 1 regulatory subunit 12A
  KO
K06270  protein phosphatase 1 regulatory subunit 12A
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04270  Vascular smooth muscle contraction
hsa04510  Focal adhesion
hsa04611  Platelet activation
hsa04810  Regulation of actin cytoskeleton
hsa04921  Oxytocin signaling pathway
hsa05205  Proteoglycans in cancer
Disease
H02523  Genitourinary and/or brain malformation syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    4659 (PPP1R12A)
   04022 cGMP-PKG signaling pathway
    4659 (PPP1R12A)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    4659 (PPP1R12A)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    4659 (PPP1R12A)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    4659 (PPP1R12A)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    4659 (PPP1R12A)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    4659 (PPP1R12A)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    4659 (PPP1R12A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    4659 (PPP1R12A)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     4659 (PPP1R12A)
SSDB
Motif
Pfam: Ank_2 Ank_4 PRKG1_interact Ank_5 Ank Ank_3
Other DBs
NCBI-GeneID: 4659
NCBI-ProteinID: NP_001137357
OMIM: 602021
HGNC: 7618
Ensembl: ENSG00000058272
Pharos: O14974(Tbio)
UniProt: O14974 B2RAH5
Structure
LinkDB
Position
12:complement(79773563..79935460)
AA seq 1030 aa
MKMADAKQKRNEQLKRWIGSETDLEPPVVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLL
HRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLD
IAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRD
ARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAA
HWGKEEACRILVDNLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSP
LIESTANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEKVDEEEEGKKDESSCSSEED
EEDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATK
ISPKEEERKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSL
DNKEKEKDSKGTRLAYVAPTIPRRLASTSDIEEKENRDSSSLRTSSSYTRRKWEDDLKKN
SSVNEGSTYHKSCSFGRRQDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGS
SSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTAGTVSSTT
EVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTR
EQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTP
SSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSI
RERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAGDR
YDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDL
KLQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGA
LIRVISKLSK
NT seq 3093 nt   +upstreamnt  +downstreamnt
atgaagatggcggacgcgaagcagaagcggaacgagcagctgaaacgctggatcggctcc
gagacggacctcgagcctccggtggtgaagcgccagaagaccaaggtgaagttcgacgat
ggcgccgtcttcctggctgcttgctccagcggcgacacggacgaggtcctcaagctgctg
caccgcggcgccgacatcaattacgccaatgtggacggactcactgccctgcaccaggct
tgcattgatgacaatgttgatatggtgaagtttctggtagaaaatggagcaaatattaat
caacctgataatgaaggctggataccactacatgcagcagcttcctgtggatatcttgat
attgcagagtttttgattggtcaaggagcacatgtaggggctgtcaacagtgaaggagat
acacctttagatattgcggaggaggaggcaatggaagagctacttcaaaatgaagttaat
cggcaaggggttgatatagaagcagctcgaaaggaagaagaacggatcatgcttagagat
gccaggcagtggctaaatagtggtcatataaatgatgtccggcatgcaaaatctggaggt
acagcacttcacgttgcagctgctaaaggctatacggaagttttaaaacttttaatacag
gcaggctatgatgttaatattaaagactatgatggctggacacctcttcatgctgcagct
cattggggtaaagaagaagcatgtcgaattttagtggacaatctgtgtgatatggagatg
gtcaacaaagtgggccaaacagcctttgatgtagcagatgaagacattttaggatattta
gaagagttgcaaaagaaacaaaatctgctccatagtgaaaaacgggacaagaaatctcca
ctaattgaatcaacagcaaatatggacaataatcagtcacagaagacctttaaaaacaaa
gagacgttgattattgaaccagagaaaaatgcatcccgtattgaatctctggaacaagaa
aaggttgatgaagaagaagaaggaaagaaggatgagtctagctgctctagtgaagaagat
gaggaagatgactcggaatcagaagctgaaacagataagacaaaacccctggcttctgta
actaatgccaacacttctagtacacaagcagctcctgtagctgttacaacacctactgtg
tcatcaggtcaagcaacacctacatcacctattaaaaagtttccaaccacagctacaaaa
atttctcccaaagaagaagagagaaaagatgagtctcctgcaacttggaggttaggactt
agaaagacgggcagctatggtgcacttgctgaaatcacagcatctaaagagggtcagaaa
gaaaaagatactgcaggtgttacacgttcagcttcaagtcccagactttcctcctctttg
gataataaagaaaaggagaaagatagtaaaggaactaggcttgcatatgttgcacctaca
ataccaagacgactagccagtacatctgacattgaagagaaagaaaacagagattcttca
agtttgcgaacaagtagttcatatacaaggagaaaatgggaagatgatcttaaaaaaaat
agctcagttaatgaaggatcaacgtatcataaaagttgctcctttggtagaagacaagat
gatttgattagttctagtgttccaagcaccacatcaacaccaacagttacctctgcagct
gggcttcagaaaagcctgctttccagcacaagcactactacaaagattacaacgggttct
tcctcagcaggcacacaaagcagtacctcaaatcgtttgtgggctgaggatagtactgag
aaagaaaaggacagtgttcctacggcagtgaccattcctgttgctccaactgttgtaaat
gctgcagcttctaccacaaccctgactacaactactgctggcactgtctcctccacaaca
gaggtcagggagagacgcagatcatacctcactcctgttagggatgaagagtctgaatcc
caaagaaaagcaagatctagacaagcaagacaatctagaagatcaacacagggagtgaca
ttaactgatcttcaagaagctgagaaaacaataggaagaagtcgttctacccgaaccaga
gaacaagaaaatgaagaaaaagaaaaagaggaaaaagagaaacaagataaagagaaacaa
gaagaaaagaaggagtcagaaacatctagagaagatgaatataaacaaaagtactccaga
acgtatgatgagacttaccagcgttataggccagtatcaacttcaagttcaaccactcca
tcctcttcactttctactatgagcagttcactgtatgcttcaagtcaactaaacaggcca
aatagtcttgtaggcataacttctgcttactccagaggaataacaaaagaaaatgaaaga
gagggagaaaaaagagaagaggagaaagaaggagaagataaatcacaacctaaatcaatc
agagaacgacgacgaccaagagagaaaagaagatctacaggagtttcattttggacacaa
gatagtgatgaaaatgaacaagaacaacaatcagacacagaagagggatccaataagaaa
gaaactcagacggattccatttctagatatgaaaccagttctacatcagctggtgatcga
tatgattccttgctgggtcgctctggatcatacagttacttagaagaaagaaaaccttac
agcagcaggctagaaaaggatgactcaactgactttaaaaagctttatgaacaaattcta
gctgaaaatgaaaagctgaaggcacagctacatgatacaaatatggaactaacagatctt
aaattacagttggaaaaggccacccagagacaagaaagatttgctgatagatcactgttg
gaaatggaaaaaagggaacgaagagctctagaaagaagaatatctgaaatggaagaagag
ctcaaaatgttaccagacctaaaagcagacaaccagaggctaaaggatgaaaatggggcc
ttgatcagagttataagcaaactttccaaataa

KEGG   Homo sapiens (human): 4660
Entry
4660              CDS       T01001                                 
Symbol
PPP1R12B, MYPT2, PP1bp55
Name
(RefSeq) protein phosphatase 1 regulatory subunit 12B
  KO
K12329  protein phosphatase 1 regulatory subunit 12B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04270  Vascular smooth muscle contraction
hsa04510  Focal adhesion
hsa04810  Regulation of actin cytoskeleton
hsa04921  Oxytocin signaling pathway
hsa05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    4660 (PPP1R12B)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    4660 (PPP1R12B)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    4660 (PPP1R12B)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    4660 (PPP1R12B)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    4660 (PPP1R12B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    4660 (PPP1R12B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     4660 (PPP1R12B)
SSDB
Motif
Pfam: PRKG1_interact Ank_4 Ank_2 Ank_5 Ank Ank_3 MEDS
Other DBs
NCBI-GeneID: 4660
NCBI-ProteinID: NP_002472
OMIM: 603768
HGNC: 7619
Ensembl: ENSG00000077157
Pharos: O60237(Tbio)
UniProt: O60237
LinkDB
Position
1:202348699..202592702
AA seq 982 aa
MAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDGA
VFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQ
DNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQ
GVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAG
YELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEL
LQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEENKESSSS
SSEEEEGEDEASESETEKEADKKPEAFVNHSNSESKSSITEQIPAPAQNTFSASSARRFS
SGLFNKPEEPKDESPSSWRLGLRKTGSHNMLSEVANSREPIRDRGSSIYRSSSSPRISAL
LDNKDKERENKSYISSLAPRKLNSTSDIEEKENRESAVNLVRSGSYTRQLWRDEAKGNEI
PQTIAPSTYVSTYLKRTPHKSQADTTAEKTADNVSSSTPLCVITNRPLPSTANGVTATPV
LSITGTDSSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERT
FSRSRAERQAQEQPREKPTDTEGLEGSPEKHEPSAVPATEAGEGQQPWGRSLDEEPICHR
LRCPAQPDKPTTPASPSTSRPSLYTSSHLLWTNRFSVPDSESSETTTNTTTAKEMDKNEN
EEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESG
GSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKL
QEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELK
SDNQRLKDENGALIRVISKLSK
NT seq 2949 nt   +upstreamnt  +downstreamnt
atggcggaactggagcacctaggagggaagcgggcagagtcggcgcgaatgcggcgggca
gagcagcttcggcgctggcggggctcgctgacagagcaggagcctgcggagcgacgaggc
gcggggcggcagccgctgaccaggcgcgggagccccagggtccgcttcgaggacggtgct
gtctttctggccgcctgctctagcggggacaccgacgaggtgagaaagcttctggcaaga
ggtgctgatatcaacacggtcaacgtggacggcttgacagccctgcaccaggcatgtatt
gatgaaaatttggacatggtgaagtttctggtggagaacagagccaatgtaaaccagcaa
gacaacgagggctggacaccccttcatgcagcagcttcctgtggctatctcaacatagca
gagtatttcattaatcacggagccagtgtaggtattgtcaatagtgaaggtgaagttccc
tctgaccttgcagaagagccagccatgaaggatcttcttctggagcaagtaaagaagcaa
ggagttgatctagagcagtcaagaaaagaagaagagcagcagatgttgcaggatgcccgc
cagtggctcaacagtgggaaaatagaggatgtgaggcaggctcgctcaggggctacagcc
cttcatgtggctgctgccaagggctactctgaagtcctcagacttttaattcaggctggc
tatgaactcaatgttcaggattatgatggctggactcccctccatgctgctgcacactgg
ggagtgaaggaggcttgctccatcctggcagaagcactttgtgacatggatattcgaaat
aaactgggccagacaccatttgatgtggctgatgagggtctcgtggagcatttggagttg
ctccagaagaagcagaatgtgcttcgaagtgaaaaggagacacggaataaactcattgag
tcagatctgaacagcaagattcagagtgggttctttaagaacaaagagaagatgctctat
gaggaggagacacctaagtcccaagaaatggaggaagaaaataaagaatctagtagctcc
agctcagaggaggaggaaggtgaagatgaagcttctgagtcagaaactgagaaggaggca
gataaaaagccagaagcctttgtcaatcattccaactctgaaagcaagagtagtatcaca
gagcagataccagcaccagctcaaaataccttctctgcctcttctgctaggaggttctct
tctggcctttttaacaagccagaagagcccaaagatgaatctccttcttcatggagattg
ggactgagaaaaactggcagccacaacatgctgagtgaggtggccaattccagggaacct
ataagggaccgaggctcttccatctatcgctcctcttcaagccctcggatttctgctcta
ctggacaacaaagataaggagagagaaaacaaaagctatattagttcactagcaccccgg
aagctcaacagcacaagtgatattgaagaaaaggagaacagagaatcagctgttaatcta
gtgaggagtggctcctatacccggcagctatggagggatgaagcaaaaggaaatgaaatc
ccacagacaattgctccctccacctatgtatcaacttacttgaaaaggactcctcacaaa
tcccaggccgacacaacagcagagaaaacagcagacaatgtctcttctagcaccccgctc
tgtgtgatcaccaatcgccctcttcctagcactgccaatggggttacagctactcctgtg
ctctccattactggaacagattcctctgtggaagccagggagaagaggaggtcctatctg
actcctgtacgggatgaggaagcagagtctttacggaaagcacgctccagacaagctcgg
cagacacgaaggtctactcaaggtgtcaccctaacagaccttcaagaagcagaaaggaca
ttcagccggtcgagggcagagaggcaagctcaggagcagcctcgtgagaagcccacagac
actgaagggcttgaggggagccctgagaagcatgagccctcagcagttccagcaacagaa
gctggggagggccagcagccctggggcaggagtctggatgaagagcctatctgtcatcgc
ctgaggtgcccagctcagccagacaaacccaccacgccagcatctccttctacgtcaaga
ccctcactctacaccagttcccacctgctatggacaaatagattttcagtccctgattct
gagagttcagagactaccacaaacactacaactgcaaaggaaatggacaaaaatgagaat
gaagaagcagatttggatgagcagtcctctaagaggctgtccatccgagagaggaggcgg
cccaaggaacgacgaagaggcacaggcatcaatttctggacaaaggatgaggatgaaact
gatggctctgaagaggtcaaagaaacgtggcatgaaagactttctaggttggaatcggga
ggtagtaatcctacaaccagtgattcttacggtgaccgggcttcagcaagagcccgtcgg
gaggcccgggaggcccgcctagccaccctgaccagccgtgtagaagaagacagcaacaga
gattataaaaaactctatgagagtgctctgactgaaaaccaaaaactgaaaacaaaactt
caggaagcccagctagagctagcagatataaagtccaagcttgagaaggtggcccagcag
aaacaagaaaagacctctgaccgatcatcagtgctggagatggagaaacgggagaggcga
gccttggagcgcaaaatgtcagaaatggaggaagaaatgaaggtgttaacagaactgaaa
tccgacaaccagaggctgaaagatgaaaatggtgccctcatcagagtcatcagcaaactg
tccaagtag

KEGG   Homo sapiens (human): 54776
Entry
54776             CDS       T01001                                 
Symbol
PPP1R12C, AAVS1, LENG3, MBS85, p84, p85
Name
(RefSeq) protein phosphatase 1 regulatory subunit 12C
  KO
K17457  protein phosphatase 1 regulatory subunit 12C
Organism
hsa  Homo sapiens (human)
Pathway
hsa04270  Vascular smooth muscle contraction
hsa04510  Focal adhesion
hsa04810  Regulation of actin cytoskeleton
hsa04921  Oxytocin signaling pathway
hsa05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    54776 (PPP1R12C)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    54776 (PPP1R12C)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    54776 (PPP1R12C)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    54776 (PPP1R12C)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    54776 (PPP1R12C)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    54776 (PPP1R12C)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     54776 (PPP1R12C)
SSDB
Motif
Pfam: PRKG1_interact Ank_2 Ank_4 Ank_5 Ank_3 Ank DUF4695
Other DBs
NCBI-GeneID: 54776
NCBI-ProteinID: NP_060077
OMIM: 613245
HGNC: 14947
Ensembl: ENSG00000125503
Pharos: Q9BZL4(Tdark)
UniProt: Q9BZL4
LinkDB
Position
19:complement(55090918..55117637)
AA seq 782 aa
MSGEDGPAAGPGAAAAAARERRREQLRQWGARAGAEPGPGERRARTVRFERAAEFLAACA
GGDLDEARLMLRAADPGPGAELDPAAPPPARAVLDSTNADGISALHQACIDENLEVVRFL
VEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESDAME
GLLKAEIARRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEARHPRTGASALHVAAAKGYI
EVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLA
DEEVLSLLEELARKQEDLRNQKEASQSRGQEPQAPSSSKHRRSSVCRLSSREKISLQDLS
KERRPGGAGGPPIQDEDEGEEGPTEPPPAEPRTLNGVSSPPHPSPKSPVQLEEAPFSRRF
GLLKTGSSGALGPPERRTAEGAPGAGLQRSASSSWLEGTSTQAKELRLARITPTPSPKLP
EPSVLSEVTKPPPCLENSSPPSRIPEPESPAKPNVPTASTAPPADSRDRRRSYQMPVRDE
ESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKAPESEKPAQSLDPSRRPRVPGVE
NSDSPAQRAEAPDGQGPGPQAAREHRKVGKEWRGPAEGEEAEPADRSQESSTLEGGPSAR
RQRWQRDLNPEPEPESEEPDGGFRTLYAELRRENERLREALTETTLRLAQLKVELERATQ
RQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKL
SK
NT seq 2349 nt   +upstreamnt  +downstreamnt
atgtccggagaggatggcccggcggctggcccgggggcggcggcggcggctgcccgggag
cggcgacgggagcagctgcggcagtggggggcgcgggcgggcgccgagcctggccccgga
gagcgccgcgcccgcaccgtccgcttcgagcgcgccgccgagttcctggcggcctgtgcg
ggcggcgacctggacgaggcgcgtctgatgctgcgcgccgccgaccctggccccggcgcc
gagctcgaccccgccgcgccgccgcccgcccgcgccgtgctggactccaccaacgccgac
ggtatcagcgccctgcaccaggcctgcattgatgagaacctggaggtggtgcgcttcttg
gtggagcagggcgccactgtgaaccaggcagacaacgagggctggacgccactgcacgtg
gccgcctcctgtggctacctagatatcgccaggtacctcctgagccacggggccaacatc
gccgccgtcaacagtgacggggacctgcccctggacctggccgagtcggacgccatggag
gggctgctgaaggcggagatcgcccgccgaggtgtggatgtggaagcagccaagcgggca
gaagaggaattgctccttcatgacacgaggtgctggctgaatgggggcgccatgccagag
gcccggcacccccgcacaggcgcctctgccctgcacgtggctgctgccaagggctacatt
gaggtgatgaggttgctccttcaggctggctacgacccagagctccgggacggggacggc
tggactcccctgcacgcagcggcacactggggcgtggaggatgcctgccgcctgctggcc
gagcatggcgggggcatggactcactgacccatgcggggcagcgtccctgtgacctggcc
gatgaggaagtactgagcctgttggaggaactggcccggaaacaggaggaccttcggaac
caaaaagaagcttcccagagccggggccaggagccccaagcgccctctagcagcaaacac
agaaggagctctgtgtgtcgtctgagcagtcgcgagaagatttccctccaggacttgtcc
aaggagcgccggcctggtggggctggggggccccccatccaggacgaggatgagggggaa
gaaggtcccaccgaaccaccccctgcagaacccagaaccctcaatggcgtctcctccccg
ccgcaccccagccctaagagtcccgtgcagcttgaagaggcccccttctccaggcgcttt
ggcctcctgaagacagggagttctggtgccctgggtccccctgaaaggcggacagcggag
ggagcccctggggctgggctgcagcgctcggcttcctcctcctggctggaagggacctcc
actcaggccaaggagctccgtcttgccagaattaccccgaccccctccccgaagctgccg
gagccctctgtcctgtctgaggtcaccaagcctcctccttgcttggagaactcctcgcct
ccctccaggattccggagcctgaatccccagcgaagccaaacgtccccacagcctccacg
gcgcccccagcggactcccgggaccgacggaggtcctaccagatgcctgtgcgggatgag
gagtcggaatcccagagaaaagctcgctcccgtctcatgcgccagtctcggaggtccaca
cagggtgtgactcttacagacctgaaggaggcagagaaggctgcagggaaggccccagag
tcagagaagccggcgcagagcctggacccttcccgaaggccccgcgtccctggagtggag
aactctgacagccctgcccagagagcagaggcgcccgacgggcagggtccgggaccgcag
gcggccagggagcaccgcaaggtcggaaaggagtggagggggcctgcggagggggaggag
gcggagccggctgaccgcagccaggagtccagcaccctggagggcggcccctcggcccgc
aggcagcggtggcagcgggacctcaacccagaacctgagccagaatcggaagagccagac
ggaggctttaggacgctgtatgcagagctgcgcagggagaacgagcggcttcgcgaggcc
ctgaccgagaccacgctgcggctggcgcagctcaaggtggagctggagcgggccacgcag
aggcaagaacgcttcgctgagaggccagccctcctggaactggagagattcgagcgcagg
gccctggaacgcaaggccgcagagctggaggaggagctgaaggccctgtctgacctccgc
gctgacaaccagcgcctcaaggatgagaatgcagcgttgatccgcgtcatcagcaaactc
tccaagtga

KEGG   Homo sapiens (human): 5499
Entry
5499              CDS       T01001                                 
Symbol
PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A
Name
(RefSeq) protein phosphatase 1 catalytic subunit alpha
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04390  Hippo signaling pathway
hsa04510  Focal adhesion
hsa04611  Platelet activation
hsa04720  Long-term potentiation
hsa04728  Dopaminergic synapse
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04810  Regulation of actin cytoskeleton
hsa04910  Insulin signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04931  Insulin resistance
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05168  Herpes simplex virus 1 infection
hsa05205  Proteoglycans in cancer
hsa05415  Diabetic cardiomyopathy
Network
nt06138  PKR-eIF2alpha signaling (viruses)
nt06168  Herpes simplex virus 1 (HSV-1)
  Element
N00572  HSV ICP34.5 to PKR-eIF2alpha signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5499 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    5499 (PPP1CA)
   04024 cAMP signaling pathway
    5499 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    5499 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5499 (PPP1CA)
   04218 Cellular senescence
    5499 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    5499 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    5499 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5499 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    5499 (PPP1CA)
   04921 Oxytocin signaling pathway
    5499 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5499 (PPP1CA)
   04270 Vascular smooth muscle contraction
    5499 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    5499 (PPP1CA)
   04720 Long-term potentiation
    5499 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    5499 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    5499 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    5499 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    5499 (PPP1CA)
   05034 Alcoholism
    5499 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    5499 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    5499 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5499 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5499 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5499 (PPP1CA)
   03041 Spliceosome [BR:hsa03041]
    5499 (PPP1CA)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     5499 (PPP1CA)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     5499 (PPP1CA)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     5499 (PPP1CA)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     5499 (PPP1CA)
Spliceosome [BR:hsa03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    5499 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 5499
NCBI-ProteinID: NP_002699
OMIM: 176875
HGNC: 9281
Ensembl: ENSG00000172531
Pharos: P62136(Tchem)
UniProt: P62136
Structure
LinkDB
Position
11:complement(67398183..67401858)
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactcgatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggcaagaatgtacagctgacagagaacgagatccgcggtctgtgcctg
aaatcccgggagatttttctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacatacacggccagtactacgaccttctgcgactatttgagtatggcggt
ttccctcccgagagcaactacctctttctgggggactatgtggacaggggcaagcagtcc
ttggagaccatctgcctgctgctggcctataagatcaagtaccccgagaacttcttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctatggtttctacgatgagtgc
aagagacgctacaacatcaaactgtggaaaaccttcactgactgcttcaactgcctgccc
atcgcggccatagtggacgaaaagatcttctgctgccacggaggcctgtccccggacctg
cagtctatggagcagattcggcggatcatgcggcccacagatgtgcctgaccagggcctg
ctgtgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaacgac
cgtggcgtctcttttacctttggagccgaggtggtggccaagttcctccacaagcacgac
ttggacctcatctgccgagcacaccaggtggtagaagacggctacgagttctttgccaag
cggcagctggtgacacttttctcagctcccaactactgtggcgagtttgacaatgctggc
gccatgatgagtgtggacgagaccctcatgtgctctttccagatcctcaagcccgccgac
aagaacaaggggaagtacgggcagttcagtggcctgaaccctggaggccgacccatcacc
ccaccccgcaattccgccaaagccaagaaatag

KEGG   Homo sapiens (human): 5500
Entry
5500              CDS       T01001                                 
Symbol
PPP1CB, HEL-S-80p, MP, NSLH2, PP-1B, PP1B, PP1beta, PP1c, PPP1CD, PPP1beta
Name
(RefSeq) protein phosphatase 1 catalytic subunit beta
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04390  Hippo signaling pathway
hsa04510  Focal adhesion
hsa04611  Platelet activation
hsa04720  Long-term potentiation
hsa04728  Dopaminergic synapse
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04810  Regulation of actin cytoskeleton
hsa04910  Insulin signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04931  Insulin resistance
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05168  Herpes simplex virus 1 infection
hsa05205  Proteoglycans in cancer
hsa05415  Diabetic cardiomyopathy
Network
nt06138  PKR-eIF2alpha signaling (viruses)
nt06168  Herpes simplex virus 1 (HSV-1)
  Element
N00572  HSV ICP34.5 to PKR-eIF2alpha signaling pathway
Disease
H00523  Noonan syndrome and related disorders
H02191  Noonan-like syndrome with loose anagen hair
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5500 (PPP1CB)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    5500 (PPP1CB)
   04024 cAMP signaling pathway
    5500 (PPP1CB)
   04022 cGMP-PKG signaling pathway
    5500 (PPP1CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5500 (PPP1CB)
   04218 Cellular senescence
    5500 (PPP1CB)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    5500 (PPP1CB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    5500 (PPP1CB)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5500 (PPP1CB)
  09152 Endocrine system
   04910 Insulin signaling pathway
    5500 (PPP1CB)
   04921 Oxytocin signaling pathway
    5500 (PPP1CB)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5500 (PPP1CB)
   04270 Vascular smooth muscle contraction
    5500 (PPP1CB)
  09156 Nervous system
   04728 Dopaminergic synapse
    5500 (PPP1CB)
   04720 Long-term potentiation
    5500 (PPP1CB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    5500 (PPP1CB)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    5500 (PPP1CB)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    5500 (PPP1CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    5500 (PPP1CB)
   05034 Alcoholism
    5500 (PPP1CB)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    5500 (PPP1CB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    5500 (PPP1CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5500 (PPP1CB)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5500 (PPP1CB)
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5500 (PPP1CB)
   03041 Spliceosome [BR:hsa03041]
    5500 (PPP1CB)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     5500 (PPP1CB)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     5500 (PPP1CB)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     5500 (PPP1CB)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     5500 (PPP1CB)
Spliceosome [BR:hsa03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    5500 (PPP1CB)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 5500
NCBI-ProteinID: NP_002700
OMIM: 600590
HGNC: 9282
Ensembl: ENSG00000213639
Pharos: P62140(Tbio)
UniProt: P62140 V9HW04
LinkDB
Position
2:28751604..28802940
AA seq 327 aa
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI
CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ
SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL
DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
KAKYQYGGLNSGRPVTPPRTANPPKKR
NT seq 984 nt   +upstreamnt  +downstreamnt
atggcggacggggagctgaacgtggacagcctcatcacccggctgctggaggtacgagga
tgtcgtccaggaaagattgtgcagatgactgaagcagaagttcgaggcttatgtatcaag
tctcgggagatctttctcagccagcctattcttttggaattggaagcaccgctgaaaatt
tgtggagatattcatggacaatatacagatttactgagattatttgaatatggaggtttc
ccaccagaagccaactatcttttcttaggagattatgtggacagaggaaagcagtctttg
gaaaccatttgtttgctattggcttataaaatcaaatatccagagaacttctttctctta
agaggaaaccatgagtgtgctagcatcaatcgcatttatggattctatgatgaatgcaaa
cgaagatttaatattaaattgtggaagaccttcactgattgttttaactgtctgcctata
gcagccattgtggatgagaagatcttctgttgtcatggaggattgtcaccagacctgcaa
tctatggagcagattcggagaattatgagacctactgatgtccctgatacaggtttgctc
tgtgatttgctatggtctgatccagataaggatgtgcaaggctggggagaaaatgatcgt
ggtgtttcctttacttttggagctgatgtagtcagtaaatttctgaatcgtcatgattta
gatttgatttgtcgagctcatcaggtggtggaagatggatatgaattttttgctaaacga
cagttggtaaccttattttcagccccaaattactgtggcgagtttgataatgctggtgga
atgatgagtgtggatgaaactttgatgtgttcatttcagatattgaaaccatctgaaaag
aaagctaaataccagtatggtggactgaattctggacgtcctgtcactccacctcgaaca
gctaatccgccgaagaaaaggtga

KEGG   Homo sapiens (human): 5501
Entry
5501              CDS       T01001                                 
Symbol
PPP1CC, PP-1G, PP1C, PPP1G
Name
(RefSeq) protein phosphatase 1 catalytic subunit gamma
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04390  Hippo signaling pathway
hsa04510  Focal adhesion
hsa04611  Platelet activation
hsa04720  Long-term potentiation
hsa04728  Dopaminergic synapse
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04810  Regulation of actin cytoskeleton
hsa04910  Insulin signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04931  Insulin resistance
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05168  Herpes simplex virus 1 infection
hsa05205  Proteoglycans in cancer
hsa05415  Diabetic cardiomyopathy
Network
nt06138  PKR-eIF2alpha signaling (viruses)
nt06168  Herpes simplex virus 1 (HSV-1)
  Element
N00572  HSV ICP34.5 to PKR-eIF2alpha signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5501 (PPP1CC)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    5501 (PPP1CC)
   04024 cAMP signaling pathway
    5501 (PPP1CC)
   04022 cGMP-PKG signaling pathway
    5501 (PPP1CC)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5501 (PPP1CC)
   04218 Cellular senescence
    5501 (PPP1CC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    5501 (PPP1CC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    5501 (PPP1CC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5501 (PPP1CC)
  09152 Endocrine system
   04910 Insulin signaling pathway
    5501 (PPP1CC)
   04921 Oxytocin signaling pathway
    5501 (PPP1CC)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5501 (PPP1CC)
   04270 Vascular smooth muscle contraction
    5501 (PPP1CC)
  09156 Nervous system
   04728 Dopaminergic synapse
    5501 (PPP1CC)
   04720 Long-term potentiation
    5501 (PPP1CC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    5501 (PPP1CC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    5501 (PPP1CC)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    5501 (PPP1CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    5501 (PPP1CC)
   05034 Alcoholism
    5501 (PPP1CC)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    5501 (PPP1CC)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    5501 (PPP1CC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5501 (PPP1CC)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5501 (PPP1CC)
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5501 (PPP1CC)
   03041 Spliceosome [BR:hsa03041]
    5501 (PPP1CC)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     5501 (PPP1CC)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     5501 (PPP1CC)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     5501 (PPP1CC)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     5501 (PPP1CC)
Spliceosome [BR:hsa03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    5501 (PPP1CC)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 5501
NCBI-ProteinID: NP_002701
OMIM: 176914
HGNC: 9283
Ensembl: ENSG00000186298
Pharos: P36873(Tchem)
UniProt: P36873 A0A024RBP2
Structure
LinkDB
Position
12:complement(110708376..110742891)
AA seq 323 aa
MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
KKKPNATRPVTPPRGMITKQAKK
NT seq 972 nt   +upstreamnt  +downstreamnt
atggcggatttagataaactcaacatcgacagcattatccaacggctgctggaagtgaga
gggtccaagcctggtaagaatgtccagcttcaggagaatgaaatcagaggactgtgctta
aagtctcgtgaaatctttctcagtcagcctatcctactagaacttgaagcaccactcaaa
atatgtggtgacatccatggacaatactatgatttgctgcgactttttgagtacggtggt
ttcccaccagaaagcaactacctgtttcttggggactatgtggacaggggaaagcagtca
ttggagacgatctgcctcttactggcctacaaaataaaatatcctgagaatttttttctt
ctcagagggaaccatgaatgtgccagcatcaacagaatttatggattttatgatgaatgt
aaaagaagatacaacattaaactatggaaaactttcacagactgttttaactgtttaccg
atagcagccatcgtggatgagaagatattctgctgtcatggaggtttatcaccagatctt
caatctatggagcagattcggcgaattatgcgaccaactgatgtaccagatcaaggtctt
ctttgtgatcttttgtggtctgaccccgataaagatgtcttaggctggggtgaaaatgac
agaggagtgtccttcacatttggtgcagaagtggttgcaaaatttctccataagcatgat
ttggatcttatatgtagagcccatcaggtggttgaagatggatatgaattttttgcaaag
aggcagttggtcactctgttttctgcgcccaattattgcggagagtttgacaatgcaggt
gccatgatgagtgtggatgaaacactaatgtgttcttttcagattttaaagcctgcagag
aaaaagaagccaaatgccacgagacctgtaacgcctccaaggggtatgatcacaaagcaa
gcaaagaaatag

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