KEGG   Homo sapiens (human): 5663
Entry
5663              CDS       T01001                                 
Symbol
PSEN1, ACNINV3, AD3, FAD, PS-1, PS1, PSNL1, S182
Name
(RefSeq) presenilin 1
  KO
K04505  presenilin 1 [EC:3.4.23.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04310  Wnt signaling pathway
hsa04330  Notch signaling pathway
hsa04722  Neurotrophin signaling pathway
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05165  Human papillomavirus infection
Network
nt06166  Human papillomavirus (HPV)
nt06460  Alzheimer disease
nt06466  Pathways of neurodegeneration
nt06511  NOTCH signaling
nt06534  Unfolded protein response
  Element
N00382  HPV E6 to Notch signaling pathway
N01007  Mutation-caused aberrant PSEN to mGluR5-Ca2+ -apoptotic pathway
N01008  Mutation-caused aberrant PSEN1 to mGluR5-Ca2+ -apoptotic pathway
N01010  Mutation-caused aberrant PSEN1 to PERK-ATF4 signaling pathway
N01012  Mutation-caused aberrant PSEN1 to IRE1a-XBP1 signaling pathway
N01016  Mutation-caused aberrant PSEN1 to ATF6-mediated transcription
N01017  Mutation-caused aberrant PSEN1 to anterograde axonal transport
N01478  Notch proteolytic activation
Disease
H00056  Alzheimer disease
H00078  Frontotemporal lobar degeneration
H00294  Dilated cardiomyopathy
H00681  Acne inversa
Drug target
Avagacestat: D09869
Begacestat: D08869
Crenigacestat: D11151
Nirogacestat (DG03016): D10960 D11453<US>
Osugacestat: D12235
Semagacestat: D09377
Tarenflurbil: D09010
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    5663 (PSEN1)
   04330 Notch signaling pathway
    5663 (PSEN1)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    5663 (PSEN1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5663 (PSEN1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    5663 (PSEN1)
   05022 Pathways of neurodegeneration - multiple diseases
    5663 (PSEN1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5663 (PSEN1)
Peptidases and inhibitors [BR:hsa01002]
 Aspartic peptidases
  Family A22: presenilin family
   5663 (PSEN1)
SSDB
Motif
Pfam: Presenilin
Other DBs
NCBI-GeneID: 5663
NCBI-ProteinID: NP_000012
OMIM: 104311
HGNC: 9508
Ensembl: ENSG00000080815
UniProt: P49768 A0A024R6A3
Structure
LinkDB
Position
14:73136417..73223691
AA seq 467 aa
MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR
QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI
YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY
LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA
VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL
TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
NT seq 1404 nt   +upstreamnt  +downstreamnt
atgacagagttacctgcaccgttgtcctacttccagaatgcacagatgtctgaggacaac
cacctgagcaatactgtacgtagccagaatgacaatagagaacggcaggagcacaacgac
agacggagccttggccaccctgagccattatctaatggacgaccccagggtaactcccgg
caggtggtggagcaagatgaggaagaagatgaggagctgacattgaaatatggcgccaag
catgtgatcatgctctttgtccctgtgactctctgcatggtggtggtcgtggctaccatt
aagtcagtcagcttttatacccggaaggatgggcagctaatctataccccattcacagaa
gataccgagactgtgggccagagagccctgcactcaattctgaatgctgccatcatgatc
agtgtcattgttgtcatgactatcctcctggtggttctgtataaatacaggtgctataag
gtcatccatgcctggcttattatatcatctctattgttgctgttctttttttcattcatt
tacttgggggaagtgtttaaaacctataacgttgctgtggactacattactgttgcactc
ctgatctggaattttggtgtggtgggaatgatttccattcactggaaaggtccacttcga
ctccagcaggcatatctcattatgattagtgccctcatggccctggtgtttatcaagtac
ctccctgaatggactgcgtggctcatcttggctgtgatttcagtatatgatttagtggct
gttttgtgtccgaaaggtccacttcgtatgctggttgaaacagctcaggagagaaatgaa
acgctttttccagctctcatttactcctcaacaatggtgtggttggtgaatatggcagaa
ggagacccggaagctcaaaggagagtatccaaaaattccaagtataatgcagaaagcaca
gaaagggagtcacaagacactgttgcagagaatgatgatggcgggttcagtgaggaatgg
gaagcccagagggacagtcatctagggcctcatcgctctacacctgagtcacgagctgct
gtccaggaactttccagcagtatcctcgctggtgaagacccagaggaaaggggagtaaaa
cttggattgggagatttcattttctacagtgttctggttggtaaagcctcagcaacagcc
agtggagactggaacacaaccatagcctgtttcgtagccatattaattggtttgtgcctt
acattattactccttgccattttcaagaaagcattgccagctcttccaatctccatcacc
tttgggcttgttttctactttgccacagattatcttgtacagccttttatggaccaatta
gcattccatcaattttatatctag

KEGG   Homo sapiens (human): 5664
Entry
5664              CDS       T01001                                 
Symbol
PSEN2, AD3L, AD4, CMD1V, PS2, STM2
Name
(RefSeq) presenilin 2
  KO
K04522  presenilin 2 [EC:3.4.23.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa04722  Neurotrophin signaling pathway
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06460  Alzheimer disease
nt06466  Pathways of neurodegeneration
nt06511  NOTCH signaling
  Element
N01007  Mutation-caused aberrant PSEN to mGluR5-Ca2+ -apoptotic pathway
N01478  Notch proteolytic activation
Disease
H00056  Alzheimer disease
H00294  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    5664 (PSEN2)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    5664 (PSEN2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    5664 (PSEN2)
   05022 Pathways of neurodegeneration - multiple diseases
    5664 (PSEN2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5664 (PSEN2)
Peptidases and inhibitors [BR:hsa01002]
 Aspartic peptidases
  Family A22: presenilin family
   5664 (PSEN2)
SSDB
Motif
Pfam: Presenilin
Other DBs
NCBI-GeneID: 5664
NCBI-ProteinID: NP_000438
OMIM: 600759
HGNC: 9509
Ensembl: ENSG00000143801
UniProt: P49810
Structure
LinkDB
Position
1:226870616..226903668
AA seq 448 aa
MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
DRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGV
KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
TFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq 1347 nt   +upstreamnt  +downstreamnt
atgctcacattcatggcctctgacagcgaggaagaagtgtgtgatgagcggacgtcccta
atgtcggctgagagccccacgccgcgctcctgccaggagggcaggcagggcccagaggat
ggagagaacactgcccagtggagaagccaggagaacgaggaggacggtgaggaggaccct
gaccgctatgtctgtagtggggttcccgggcggccgccaggcctggaggaagagctgacc
ctcaaatacggagcgaagcacgtgatcatgctgtttgtgcctgtcactctgtgcatgatc
gtggtggtagccaccatcaagtctgtgcgcttctacacagagaagaatggacagctcatc
tacacgccattcactgaggacacaccctcggtgggccagcgcctcctcaactccgtgctg
aacaccctcatcatgatcagcgtcatcgtggttatgaccatcttcttggtggtgctctac
aagtaccgctgctacaagttcatccatggctggttgatcatgtcttcactgatgctgctg
ttcctcttcacctatatctaccttggggaagtgctcaagacctacaatgtggccatggac
taccccaccctcttgctgactgtctggaacttcggggcagtgggcatggtgtgcatccac
tggaagggccctctggtgctgcagcaggcctacctcatcatgatcagtgcgctcatggcc
ctagtgttcatcaagtacctcccagagtggtccgcgtgggtcatcctgggcgccatctct
gtgtatgatctcgtggctgtgctgtgtcccaaagggcctctgagaatgctggtagaaact
gcccaggagagaaatgagcccatattccctgccctgatatactcatctgccatggtgtgg
acggttggcatggcgaagctggacccctcctctcagggtgccctccagctcccctacgac
ccggagatggaagaagactcctatgacagttttggggagccttcataccccgaagtcttt
gagcctcccttgactggctacccaggggaggagctggaggaagaggaggaaaggggcgtg
aagcttggcctcggggacttcatcttctacagtgtgctggtgggcaaggcggctgccacg
ggcagcggggactggaataccacgctggcctgcttcgtggccatcctcattggcttgtgt
ctgaccctcctgctgcttgctgtgttcaagaaggcgctgcccgccctccccatctccatc
acgttcgggctcatcttttacttctccacggacaacctggtgcggccgttcatggacacc
ctggcctcccatcagctctacatctga

KEGG   Homo sapiens (human): 55851
Entry
55851             CDS       T01001                                 
Symbol
PSENEN, ACNINV2, MDS033, MSTP064, PEN-2, PEN2
Name
(RefSeq) presenilin enhancer, gamma-secretase subunit
  KO
K06170  presenilin enhancer 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa05010  Alzheimer disease
Network
nt06511  NOTCH signaling
  Element
N01478  Notch proteolytic activation
Disease
H00681  Acne inversa
Drug target
Avagacestat: D09869
Begacestat: D08869
Crenigacestat: D11151
Nirogacestat (DG03016): D10960 D11453<US>
Osugacestat: D12235
Semagacestat: D09377
Tarenflurbil: D09010
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    55851 (PSENEN)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    55851 (PSENEN)
SSDB
Motif
Pfam: PEN-2
Other DBs
NCBI-GeneID: 55851
NCBI-ProteinID: NP_001268461
OMIM: 607632
HGNC: 30100
Ensembl: ENSG00000205155
UniProt: Q9NZ42
Structure
LinkDB
Position
19:35745651..35747519
AA seq 101 aa
MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLVPAYTEQSQIKGYVWRS
AVGFLFWVIVLTSWITIFQIYRPRWGALGDYLSFTIPLGTP
NT seq 306 nt   +upstreamnt  +downstreamnt
atgaacctggagcgagtgtccaatgaggagaaattgaacctgtgccggaagtactacctg
ggggggtttgctttcctgccttttctctggttggtcaacatcttctggttcttccgagag
gccttccttgtcccagcctacacagaacagagccaaatcaaaggctatgtctggcgctca
gctgtgggcttcctcttctgggtgatagtgctcacctcctggatcaccatcttccagatc
taccggccccgctggggtgcccttggggactacctctccttcaccatacccctgggcacc
ccctga

KEGG   Homo sapiens (human): 23385
Entry
23385             CDS       T01001                                 
Symbol
NCSTN, ATAG1874
Name
(RefSeq) nicastrin
  KO
K06171  nicastrin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa05010  Alzheimer disease
Network
nt06511  NOTCH signaling
  Element
N01478  Notch proteolytic activation
Disease
H00681  Acne inversa
Drug target
Avagacestat: D09869
Begacestat: D08869
Crenigacestat: D11151
Nirogacestat (DG03016): D10960 D11453<US>
Osugacestat: D12235
Semagacestat: D09377
Tarenflurbil: D09010
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    23385 (NCSTN)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    23385 (NCSTN)
SSDB
Motif
Pfam: Nicastrin Ncstrn_small Peptidase_M28
Other DBs
NCBI-GeneID: 23385
NCBI-ProteinID: NP_056146
OMIM: 605254
HGNC: 17091
Ensembl: ENSG00000162736
UniProt: Q92542
Structure
LinkDB
Position
1:160343383..160358949
AA seq 709 aa
MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQI
GCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAG
LAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPI
FLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTF
SINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVA
SFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVD
SFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQ
PLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFV
TDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQ
DLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLY
EYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIRARI
FLIASKELELITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY
NT seq 2130 nt   +upstreamnt  +downstreamnt
atggctacggcagggggtggctctggggctgacccgggaagtcggggtctccttcgcctt
ctgtctttctgcgtcctactagcaggtttgtgcaggggaaactcagtggagaggaagata
tatatccccttaaataaaacagctccctgtgttcgcctgctcaacgccactcatcagatt
ggctgccagtcttcaattagtggagacacaggggttatccacgtagtagagaaagaggag
gacctacagtgggtattgactgatggccccaaccccccttacatggttctgctggagagc
aagcattttaccagggatttaatggagaagctgaaagggagaaccagccgaattgctggt
cttgcagtgtccttgaccaagcccagtcctgcctcaggcttctctcctagtgtacagtgc
ccaaatgatgggtttggtgtttactccaattcctatgggccagagtttgctcactgcaga
gaaatacagtggaattcgctgggcaatggtttggcttatgaagactttagtttccccatc
tttcttcttgaagatgaaaatgaaaccaaagtcatcaagcagtgctatcaagatcacaac
ctgagtcagaatggctcagcaccaaccttcccactatgtgccatgcagctcttttcacac
atgcatgctgtcatcagcactgccacctgcatgcggcgcagctccatccaaagcaccttc
agcatcaacccagaaatcgtctgtgaccccctgtctgattacaatgtgtggagcatgcta
aagcctataaatacaactgggacattaaagcctgacgacagggttgtggttgctgccacc
cggctggatagtcgttcctttttctggaatgtggccccaggggctgaaagcgcagtggct
tcctttgtcacccagctggctgctgctgaagctttgcaaaaggcacctgatgtgaccacc
ctgccccgcaatgtcatgtttgtcttctttcaaggggaaacttttgactacattggcagc
tcgaggatggtctacgatatggagaagggcaagtttcccgtgcagttagagaatgttgac
tcatttgtggagctgggacaggtggccttaagaacttcattagagctttggatgcacaca
gatcctgtttctcagaaaaatgagtctgtacggaaccaggtggaggatctcctggccaca
ttggagaagagtggtgctggtgtccctgctgtcatcctcaggaggccaaatcagtcccag
cctctcccaccatcttccctgcagcgatttcttcgagctcgaaacatctctggcgttgtt
ctggctgaccactctggtgccttccataacaaatattaccagagtatttacgacactgct
gagaacattaatgtgagctatcccgaatggctgagccctgaagaggacctgaactttgta
acagacactgccaaggccctggcagatgtggccacggtgctgggacgtgctctgtatgag
cttgcaggaggaaccaacttcagcgacacagttcaggctgatccccaaacggttacccgc
ctgctctatgggttcctgattaaagccaacaactcatggttccagtctatcctcaggcag
gacctaaggtcctacttgggtgacgggcctcttcaacattacatcgctgtctccagcccc
accaacaccacttatgttgtacagtatgccttggcaaatttgactggcacagtggtcaac
ctcacccgagagcagtgccaggatccaagtaaagtcccaagtgaaaacaaggatctgtat
gagtactcatgggtccagggccctttgcattctaatgagacggaccgactcccccggtgt
gtgcgttctactgcacgattagccagggccttgtctcctgcctttgaactgagtcagtgg
agctctactgaatactctacatggactgagagccgctggaaagatatccgtgcccggata
tttctcatcgccagcaaagagcttgagttgatcaccctgacagtgggcttcggcatcctc
atcttctccctcatcgtcacctactgcatcaatgccaaagctgatgtccttttcattgct
ccccgggagccaggagctgtgtcatactga

KEGG   Homo sapiens (human): 51107
Entry
51107             CDS       T01001                                 
Symbol
APH1A, 6530402N02Rik, APH-1, APH-1A, CGI-78
Name
(RefSeq) aph-1 homolog A, gamma-secretase subunit
  KO
K06172  gamma-secretase subunit APH-1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa05010  Alzheimer disease
Network
nt06511  NOTCH signaling
  Element
N01478  Notch proteolytic activation
Drug target
Avagacestat: D09869
Begacestat: D08869
Crenigacestat: D11151
Nirogacestat (DG03016): D10960 D11453<US>
Osugacestat: D12235
Semagacestat: D09377
Tarenflurbil: D09010
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    51107 (APH1A)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    51107 (APH1A)
SSDB
Motif
Pfam: Aph-1 Peptidase_M3_N HTH_58 BRI3BP
Other DBs
NCBI-GeneID: 51107
NCBI-ProteinID: NP_001071096
OMIM: 607629
HGNC: 29509
Ensembl: ENSG00000117362
UniProt: Q96BI3
Structure
LinkDB
Position
1:complement(150265404..150269016)
AA seq 265 aa
MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
RSLLCRRQEDSRVMVYSALRIPPED
NT seq 798 nt   +upstreamnt  +downstreamnt
atgggggctgcggtgtttttcggctgcactttcgtcgcgttcggcccggccttcgcgctt
ttcttgatcactgtggctggggacccgcttcgcgttatcatcctggtcgcaggggcattt
ttctggctggtctccctgctcctggcctctgtggtctggttcatcttggtccatgtgacc
gaccggtcagatgcccggctccagtacggcctcctgatttttggtgctgctgtctctgtc
cttctacaggaggtgttccgctttgcctactacaagctgcttaagaaggcagatgagggg
ttagcatcgctgagtgaggacggaagatcacccatctccatccgccagatggcctatgtt
tctggtctctccttcggtatcatcagtggtgtcttctctgttatcaatattttggctgat
gcacttgggccaggtgtggttgggatccatggagactcaccctattacttcctgacttca
gcctttctgacagcagccattatcctgctccataccttttggggagttgtgttctttgat
gcctgtgagaggagacggtactgggctttgggcctggtggttgggagtcacctactgaca
tcgggactgacattcctgaacccctggtatgaggccagcctgctgcccatctatgcagtc
actgtttccatggggctctgggccttcatcacagctggagggtccctccgaagtattcag
cgcagcctcttgtgccgacggcaggaggacagtcgggtgatggtgtattctgccctgcgc
atcccacccgaggactga

KEGG   Homo sapiens (human): 83464
Entry
83464             CDS       T01001                                 
Symbol
APH1B, APH-1B, PRO1328, PSFL, TAAV688, aph-1beta
Name
(RefSeq) aph-1 homolog B, gamma-secretase subunit
  KO
K06172  gamma-secretase subunit APH-1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
hsa05010  Alzheimer disease
Network
nt06511  NOTCH signaling
  Element
N01478  Notch proteolytic activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    83464 (APH1B)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    83464 (APH1B)
SSDB
Motif
Pfam: Aph-1
Other DBs
NCBI-GeneID: 83464
NCBI-ProteinID: NP_112591
OMIM: 607630
HGNC: 24080
Ensembl: ENSG00000138613
UniProt: Q8WW43
Structure
LinkDB
Position
15:63277605..63309126
AA seq 257 aa
MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII
DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYVS
GLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFDG
CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL
CLLCQDKNFLLYNQRSR
NT seq 774 nt   +upstreamnt  +downstreamnt
atgactgcggccgtgttcttcggctgcgccttcattgccttcgggcctgcgctcgccctt
tatgtcttcaccatcgccaccgagccgttgcgtatcatcttcctcatcgccggagctttc
ttctggttggtgtctctactgatttcgtcccttgtttggttcatggcaagagtcattatt
gacaacaaagatggaccaacacagaaatatctgctgatctttggagcgtttgtctctgtc
tatatccaagaaatgttccgatttgcatattataaactcttaaaaaaagccagtgaaggt
ttgaagagtataaacccaggtgagacagcaccctctatgcgactgctggcctatgtttct
ggcttgggctttggaatcatgagtggagtattttcctttgtgaataccctatctgactcc
ttggggccaggcacagtgggcattcatggagattctcctcaattcttcctttattcagct
ttcatgacgctggtcattatcttgctgcatgtattctggggcattgtattttttgatggc
tgtgagaagaaaaagtggggcatcctccttatcgttctcctgacccacctgctggtgtca
gcccagaccttcataagttcttattatggaataaacctggcgtcagcatttataatcctg
gtgctcatgggcacctgggcattcttagctgcgggaggcagctgccgaagcctgaaactc
tgcctgctctgccaagacaagaactttcttctttacaaccagcgctccagataa

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