KEGG   Homo sapiens (human): 57617
Entry
57617             CDS       T01001                                 
Symbol
VPS18, PEP3
Name
(RefSeq) VPS18 core subunit of CORVET and HOPS complexes
  KO
K20181  vacuolar protein sorting-associated protein 18
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04148  Efferocytosis
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06532  Autophagy
  Element
N01300  Tethering of late endosomes and lysosomes
N01301  Salmonella SifA to Tethering of late endosomes and lysosomes
N01721  Autophagosome and lysosome fusion, tethering factor
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    57617 (VPS18)
   04148 Efferocytosis
    57617 (VPS18)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    57617 (VPS18)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    57617 (VPS18)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Tethering complex
   CORVET complex
    57617 (VPS18)
   Hops complex
    57617 (VPS18)
SSDB
Motif
Pfam: Pep3_Vps18 Clathrin zf-RING_5 Vps39_2 zf-C3HC4_2 zf-RING_16 KNOX2 zf-ANAPC11 zf-RING_2 zf-RING_UBOX zf-rbx1 CNH zf-C3HC4
Other DBs
NCBI-GeneID: 57617
NCBI-ProteinID: NP_065908
OMIM: 608551
HGNC: 15972
Ensembl: ENSG00000104142
UniProt: Q9P253
LinkDB
Position
15:40894450..40903975
AA seq 973 aa
MASILDEYENSLSRSAVLQPGCPSVGIPHSGYVNAQLEKEVPIFTKQRIDFTPSERITSL
VVSSNQLCMSLGKDTLLRIDLGKANEPNHVELGRKDDAKVHKMFLDHTGSHLLIALSSTE
VLYVNRNGQKVRPLARWKGQLVESVGWNKALGTESSTGPILVGTAQGHIFEAELSASEGG
LFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRSFVIATTRQRLFQFIGRAAEGAE
AQGFSGLFAAYTDHPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGALDCG
RPDSLLSEERVWEYPEGVGPGASPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFL
EKFGPLKHMVKDSSTGQLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPD
CLDTVLAREADFCFRQRRYLESARCYALTQSYFEEIALKFLEARQEEALAEFLQRKLASL
KPAERTQATLLTTWLTELYLSRLGALQGDPEALTLYRETKECFRTFLSSPRHKEWLFASR
ASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSP
ILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEVQQVSQAIRYMEFCVNVLGETE
QAIHNYLLSLYARGRPDSLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVL
ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC
PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQEL
RGRYGTVEPQDKCATCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQR
KLGAAPPPAKGSARAKEAEGGAATAGPSREQLKADLDELVAAECVYCGELMIRSIDRPFI
DPQRYEEEQLSWL
NT seq 2922 nt   +upstreamnt  +downstreamnt
atggcgtccatcctggatgagtacgagaactcgctgtcccgctcggccgtcttgcagccc
ggctgccctagcgtgggcatcccccactcggggtatgtgaatgcccagctggagaaggaa
gtgcccatcttcacaaagcagcgcattgacttcaccccttccgagcgcattaccagtctt
gtcgtctccagcaatcagctgtgcatgagcctgggcaaggatacactgctccgcattgac
ttgggcaaggcaaatgagcccaaccacgtggagctgggacgtaaggatgacgcaaaagtt
cacaagatgttccttgaccatactggctctcacctgctgattgccctgagcagcacggag
gtcctctacgtgaaccgaaatggacagaaggtacggccactagcacgctggaaggggcag
ctggtggagagtgtgggttggaacaaggcactgggcacggagagcagcacaggccccatc
ctggtcgggactgcccaaggccacatctttgaagcagagctctcagccagcgaaggtggg
cttttcggccctgctccggatctctacttccgcccattgtacgtgctaaatgaagaaggg
ggtccagcacctgtgtgctcccttgaggccgagcggggccctgatgggcgtagctttgtt
attgccaccactcggcagcgcctcttccagttcataggccgagcagcagagggggctgag
gcccagggtttctcagggctctttgcagcttacacggaccacccacccccattccgtgag
tttcccagcaacctgggctacagtgagttggccttctacacccccaagctgcgctccgca
ccccgggccttcgcctggatgatgggggatggtgtgttgtatggggcattggactgtggg
cgccctgactctctgctgagcgaggagcgagtctgggagtacccagagggggtagggcct
ggggccagcccacccctagccatcgtcttgacccagttccacttcctgctgctactggca
gaccgggtggaggcagtgtgcacactgaccgggcaggtggtgctgcgggatcacttcctg
gagaaatttgggccgctgaagcacatggtgaaggactcctccacaggccagctgtgggcc
tacactgagcgggctgtcttccgctaccacgtgcaacgggaggcccgagatgtctggcgc
acctatctggacatgaaccgcttcgatctggccaaagagtattgtcgagagcggcccgac
tgcctggacacggtcctggcccgggaggccgatttctgctttcgccagcgtcgctacctg
gagagcgcacgctgctatgccctgacccagagctactttgaggagattgccctcaagttc
ctggaggcccgacaggaggaggctctggctgagttcctgcagcgaaaactggccagtttg
aagccagccgaacgtacccaggccacactgctgaccacctggctgacagagctctacctg
agccggcttggggctctgcagggcgacccagaggccctgactctctaccgagaaaccaag
gaatgctttcgaaccttcctcagcagcccccgccacaaagagtggctctttgccagccgg
gcctctatccatgagctgctcgccagtcatggggacacagaacacatggtgtactttgca
gtgatcatgcaggactatgagcgggtggtggcttaccactgtcagcacgaggcctacgag
gaggccctggccgtgctcgcccgccaccgtgacccccagctcttctacaagttctcaccc
atcctcatccgtcacatcccccgccagcttgtagatgcctggattgagatgggcagccgg
ctggatgctcgtcagctcattcctgccctggtgaactacagccagggtggtgaggtccag
caggtgagccaggccatccgctacatggagttctgcgtgaacgtgctgggggagactgag
caggccatccacaactacctgctgtcactgtatgcccgtggccggccggactcactactg
gcctatctggagcaggctggggccagcccccaccgggtgcattacgacctcaagtatgcg
ctgcggctctgcgccgagcatggccaccaccgcgcttgtgtccatgtctacaaggtccta
gagctgtatgaggaggccgtggacctggccctgcaggtggatgtggacctggccaagcag
tgtgcagacctgcctgaggaggatgaggaattgcgcaagaagctgtggctgaagatcgca
cggcacgtggtgcaggaagaggaagatgtacagacagccatggcttgcctggctagctgc
cccttgctcaagattgaggatgtgctgcccttctttcctgatttcgtcaccatcgaccac
ttcaaggaggcgatctgcagctcacttaaggcctacaaccaccacatccaggagctgcag
cgggagatggaagaggctacagccagtgcccagcgcatccggcgagacctgcaggagctg
cggggccgctacggcactgtggagccccaggacaaatgtgccacctgcgacttccccctg
ctcaaccgccctttttacctcttcctctgtggccatatgttccatgctgactgcctgctg
caggctgtgcgacctggcctgccagcctacaagcaggcccggctggaggagctgcagagg
aagctgggggctgctccacccccagccaagggctctgcccgggccaaggaggccgagggt
ggggctgccacggcagggcccagccgggaacagctcaaggctgacctggatgagttggtg
gccgctgagtgtgtgtactgtggggagctgatgatccgctctatcgaccggccgttcatc
gacccccagcgctacgaggaggagcagctcagttggctgtag

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