 | | NETWORK: N01721 | |
| Entry |
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| Name |
Autophagosome and lysosome fusion, tethering factor
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| Definition |
RAB7 == (EPG5,PLEKHM1,BIRC6,HOPS,TECPR2) == LC3-II |
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| Expanded |
7879,338382 == (57724,9842,57448,(55823+64601+57617+65082+23339+27072),9895) == ((84557,81631,643246,440738)+C00350) |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 7879 | RAB7A; RAB7A, member RAS oncogene family |
| 338382 | RAB7B; RAB7B, member RAS oncogene family |
| 57724 | EPG5; ectopic P-granules 5 autophagy tethering factor |
| 9842 | PLEKHM1; pleckstrin homology and RUN domain containing M1 |
| 57448 | BIRC6; baculoviral IAP repeat containing 6 |
| 55823 | VPS11; VPS11 core subunit of CORVET and HOPS complexes |
| 64601 | VPS16; VPS16 core subunit of CORVET and HOPS complexes |
| 57617 | VPS18; VPS18 core subunit of CORVET and HOPS complexes |
| 65082 | VPS33A; VPS33A core subunit of CORVET and HOPS complexes |
| 23339 | VPS39; VPS39 subunit of HOPS complex |
| 27072 | VPS41; VPS41 subunit of HOPS complex |
| 9895 | TECPR2; tectonin beta-propeller repeat containing 2 |
| 84557 | MAP1LC3A; microtubule associated protein 1 light chain 3 alpha |
| 81631 | MAP1LC3B; microtubule associated protein 1 light chain 3 beta |
| 643246 | MAP1LC3B2; microtubule associated protein 1 light chain 3 beta 2 |
| 440738 | MAP1LC3C; microtubule associated protein 1 light chain 3 gamma |
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| Metabolite |
| C00350 | Phosphatidylethanolamine |
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| Reference |
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| Authors |
Zhao YG, Zhang H |
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| Title |
Autophagosome maturation: An epic journey from the ER to lysosomes. |
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| Journal |
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| Reference |
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| Authors |
Yu L, Chen Y, Tooze SA |
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| Title |
Autophagy pathway: Cellular and molecular mechanisms. |
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| Journal |
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| LinkDB |
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