KEGG   Homo sapiens (human): 65082
Entry
65082             CDS       T01001                                 
Symbol
VPS33A, MPSPS
Name
(RefSeq) VPS33A core subunit of CORVET and HOPS complexes
  KO
K20182  vacuolar protein sorting-associated protein 33A
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04148  Efferocytosis
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06532  Autophagy
  Element
N01300  Tethering of late endosomes and lysosomes
N01301  Salmonella SifA to Tethering of late endosomes and lysosomes
N01721  Autophagosome and lysosome fusion, tethering factor
Disease
H02205  Mucopolysaccharidosis-plus syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    65082 (VPS33A)
   04148 Efferocytosis
    65082 (VPS33A)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    65082 (VPS33A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    65082 (VPS33A)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Tethering complex
   CORVET complex
    65082 (VPS33A)
   Hops complex
    65082 (VPS33A)
SSDB
Motif
Pfam: Sec1 Pectinesterase DTP-pb9_A-dom_C
Other DBs
NCBI-GeneID: 65082
NCBI-ProteinID: NP_075067
OMIM: 610034
HGNC: 18179
Ensembl: ENSG00000139719
UniProt: Q96AX1
Structure
LinkDB
Position
12:complement(122229564..122266494)
AA seq 596 aa
MAAHLSYGRVNLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEV
EKMFTLKGNRLPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLL
CEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLM
TLQALYGTIPQIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPL
ATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIR
DKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAEL
IKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL
KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDDVNEQ
NPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPG
ENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF
NT seq 1791 nt   +upstreamnt  +downstreamnt
atggcggctcatctgtcctacggccgagtgaacctaaacgtgttgcgcgaggcggtgcgt
cgcgagctgcgcgagttcctggacaagtgcgcaggaagcaaggcaatagtttgggatgaa
tacctaactggaccctttggcctgattgcacagtattcactattgaaggaacatgaagtg
gaaaaaatgttcacacttaaaggaaatcgtttgccggcagctgatgtgaagaatataatt
ttttttgtcagacccaggctagagttgatggatataatcgctgaaaacgtgctcagtgaa
gatagacgaggcccaacgagagattttcatattctgtttgtgccacgccgtagcctgttg
tgcgaacagcggttgaaggatctgggtgtcttgggatcctttattcacagggaggagtac
agcttagatctcattccattcgatggggatctcttatccatggaatcagagggtgcattc
aaagagtgctacctggagggtgaccagacgagcctgtaccacgcagccaaggggctgatg
accctgcaagctctgtatggaacgatcccccagatctttgggaaaggagaatgcgctcgg
caagtggccaatatgatgatcaggatgaagagagagtttacaggaagccagaattcaata
tttcctgtttttgataatctcttgttgcttgatcggaatgtggatttattaacacctctt
gccactcagctgacatatgaaggactcattgatgaaatttatggcattcagaacagttat
gtgaaattacctccagagaaatttgcacctaagaaacagggcgatggtggtaaggacctc
cccacggaagcaaagaagctgcagctgaattctgcagaggagctctatgctgagatccga
gataagaacttcaacgcagttggctctgtgctcagcaagaaagcaaagatcatctctgca
gcattcgaggaaagacacaatgctaagaccgtgggggagatcaagcagtttgtttcccag
ttgccccacatgcaggcagcaaggggctcgcttgcaaaccatacctcaattgcagaattg
atcaaagatgtcactacttctgaagacttttttgataaattaaccgtggaacaggagttt
atgtctggaatagacactgataaggtcaacaattacattgaggattgtatcgcccaaaag
cactcgttgatcaaggtgttaagactagtttgcctccaatccgtgtgtaatagtgggctc
aaacaaaaagttttggattattacaaaagagagattctccagacatacggctatgagcac
atattgaccttacacaacctggagaaggccggcctgctgaaaccgcagacggggggcaga
aacaattacccaactatacggaaaacattacgcctctggatggatgatgttaatgagcaa
aaccccacggacatatcgtatgtgtacagtgggtatgccccgctcagtgtgcggctggcc
cagctgctttcccggcctggctggcggagcatcgaggaggtcctccgcatcctcccaggg
ccccactttgaggagcggcagccactgcccacaggactgcagaagaaacgtcaaccggga
gaaaaccgagtgactctgatatttttccttgggggcgtaaccttcgctgaaattgctgcc
ctgcgatttctctcccagttggaagatggaggtacagaatatgtcattgccaccactaaa
ctaatgaatggaaccagttggatagaggctctgatggaaaaacctttctag

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