| Entry |
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| Symbol |
SLC2A1, CSE, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT-1, GLUT1, GLUT1DS, HTLVR, PED, SDCHCN
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| Name |
(RefSeq) solute carrier family 2 member 1
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| KO |
| K07299 | MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1 |
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| Organism |
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| Pathway |
| hsa04919 | Thyroid hormone signaling pathway |
| hsa04920 | Adipocytokine signaling pathway |
| hsa05166 | Human T-cell leukemia virus 1 infection |
| hsa05230 | Central carbon metabolism in cancer |
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| Network |
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| Element |
| N00079 | HIF-1 signaling pathway |
| N00080 | Loss of VHL to HIF-1 signaling pathway |
| N00081 | Mutation-inactivated VHL to HIF-1 signaling pathway |
| N01784 | Glucose uptake and lactate release induced by efferocytosis |
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| Disease |
| H00232 | Hereditary stomatocytosis |
| H00808 | Idiopathic generalized epilepsies |
| H00836 | GLUT1 deficiency syndrome |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
6513 (SLC2A1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
6513 (SLC2A1)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
6513 (SLC2A1)
04922 Glucagon signaling pathway
6513 (SLC2A1)
04920 Adipocytokine signaling pathway
6513 (SLC2A1)
04919 Thyroid hormone signaling pathway
6513 (SLC2A1)
09154 Digestive system
04976 Bile secretion
6513 (SLC2A1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
6513 (SLC2A1)
05230 Central carbon metabolism in cancer
6513 (SLC2A1)
09162 Cancer: specific types
05211 Renal cell carcinoma
6513 (SLC2A1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
6513 (SLC2A1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
6513 (SLC2A1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
6513 (SLC2A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:hsa02000]
6513 (SLC2A1)
Transporters [BR:hsa02000]
Solute carrier family (SLC)
SLC2: Facilitative GLUT transporter
6513 (SLC2A1)
Major facilitator superfamily (MFS)
Sugar transporters
Sugar porter (SP) family [TC:2.A.1.1]
6513 (SLC2A1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
1:complement(42925353..42958868)
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| AA seq |
492 aa
MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
ELFHPLGADSQV |
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| NT seq |
1479 nt +upstreamnt +downstreamnt
atggagcccagcagcaagaagctgacgggtcgcctcatgctggccgtgggaggagcagtg
cttggctccctgcagtttggctacaacactggagtcatcaatgccccccagaaggtgatc
gaggagttctacaaccagacatgggtccaccgctatggggagagcatcctgcccaccacg
ctcaccacgctctggtccctctcagtggccatcttttctgttgggggcatgattggctcc
ttctctgtgggccttttcgttaaccgctttggccggcggaattcaatgctgatgatgaac
ctgctggccttcgtgtccgccgtgctcatgggcttctcgaaactgggcaagtcctttgag
atgctgatcctgggccgcttcatcatcggtgtgtactgcggcctgaccacaggcttcgtg
cccatgtatgtgggtgaagtgtcacccacagcccttcgtggggccctgggcaccctgcac
cagctgggcatcgtcgtcggcatcctcatcgcccaggtgttcggcctggactccatcatg
ggcaacaaggacctgtggcccctgctgctgagcatcatcttcatcccggccctgctgcag
tgcatcgtgctgcccttctgccccgagagtccccgcttcctgctcatcaaccgcaacgag
gagaaccgggccaagagtgtgctaaagaagctgcgcgggacagctgacgtgacccatgac
ctgcaggagatgaaggaagagagtcggcagatgatgcgggagaagaaggtcaccatcctg
gagctgttccgctcccccgcctaccgccagcccatcctcatcgctgtggtgctgcagctg
tcccagcagctgtctggcatcaacgctgtcttctattactccacgagcatcttcgagaag
gcgggggtgcagcagcctgtgtatgccaccattggctccggtatcgtcaacacggccttc
actgtcgtgtcgctgtttgtggtggagcgagcaggccggcggaccctgcacctcataggc
ctcgctggcatggcgggttgtgccatactcatgaccatcgcgctagcactgctggagcag
ctaccctggatgtcctatctgagcatcgtggccatctttggctttgtggccttctttgaa
gtgggtcctggccccatcccatggttcatcgtggctgaactcttcagccagggtccacgt
ccagctgccattgccgttgcaggcttctccaactggacctcaaatttcattgtgggcatg
tgcttccagtatgtggagcaactgtgtggtccctacgtcttcatcatcttcactgtgctc
ctggttctgttcttcatcttcacctacttcaaagttcctgagactaaaggccggaccttc
gatgagatcgcttccggcttccggcaggggggagccagccaaagtgacaagacacccgag
gagctgttccatcccctgggggctgattcccaagtgtga |
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