Homo sapiens (human): 6715 Help Entry 6715              CDS       T01001                                  Symbol SRD5A1, S5AR_1 Name (RefSeq) steroid 5 alpha-reductase 1   KO K12343   3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22] Organism hsa  Homo sapiens (human) Pathway hsa00140   Steroid hormone biosynthesis hsa01100   Metabolic pathways Module hsa_M00976   C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone hsa_M00977   C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone Network nt06019  Steroid hormone biosynthesis   Element N01541   Testosterone biosynthesis N01802   Dihydrotestosterone biosynthesis Drug target Alfatradiol:  D07121 Bexlosteride:  D03107 Dutasteride:  D03820<JP/US> Epristeride:  D01134 Idronoxil:  D04498 Izonsteride:  D04646 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     6715 (SRD5A1) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.3  Acting on the CH-CH group of donors    1.3.1  With NAD+ or NADP+ as acceptor     1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)      6715 (SRD5A1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Steroid_dh DUF1295 PEMT Motif Other DBs NCBI-GeneID:  6715 NCBI-ProteinID:  NP_001038 OMIM:  184753 HGNC:  11284 Ensembl:  ENSG00000145545 UniProt:  P18405 LinkDB All DBs Position 5:6633440..6674386 Genome browser AA seq 259 aa AA seqDB search MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQE LPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMA IMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGD TGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWY LRKFEEYPKFRKIIIPFLF NT seq 780 nt NT seq  +upstreamnt  +downstreamnt atggcaacggcgacgggggtggcggaggagcgcctgctggccgcgctcgcctacctgcag tgcgccgtgggctgcgcggtcttcgcgcgcaatcgtcagacgaactcagtgtacggccgc cacgcgctgcccagccacaggctccgagtgccggcgcgggccgcctgggtggtgcaggag ctgccctcgctggccctgccgctctaccagtacgccagcgagtccgccccgcgtctccgc agcgcgcccaactgcatcctcctggccatgttcctcgtccactacgggcatcggtgctta atttacccatttctgatgcgaggaggaaagcctatgccactgttggcgtgtacaatggcg attatgttctgtacctgtaacggctatttgcaaagcagatacttgagccattgtgcagtg tatgctgatgactgggtaacagatccccgttttctaataggttttggcttgtggttaacg ggcatgttgataaacatccattcagatcatatcctaaggaatctcagaaaaccaggagat actggatacaaaataccaaggggaggcttatttgaatacgtaactgcagccaactatttt ggagaaatcatggagtggtgtggctatgccctggccagctggtctgtccaaggcgcggct tttgctttcttcacgttttgttttttatctggtagagcaaaagagcatcatgagtggtac ctccggaaatttgaagagtatccaaagttcagaaaaattataattccatttttgttttaa

DBGET integrated database retrieval system