Homo sapiens (human): 7849
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Entry
7849 CDS
T01001
Symbol
PAX8, PAX-8
Name
(RefSeq) paired box 8
KO
K09293
paired box protein 8
Organism
hsa
Homo sapiens (human)
Pathway
hsa04918
Thyroid hormone synthesis
hsa05200
Pathways in cancer
hsa05202
Transcriptional misregulation in cancer
hsa05216
Thyroid cancer
Network
nt06240
Transcription (cancer)
nt06274
Thyroid cancer
nt06322
TRH-TSH-TH signaling
Element
N00126
PAX8-PPARG fusion to PPARG-mediated transcription
N00782
TSH-TG signaling pathway
Disease
H00032
Thyroid cancer
H00250
Congenital nongoitrous hypothyroidism (CHNG)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
7849 (PAX8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
7849 (PAX8)
05202 Transcriptional misregulation in cancer
7849 (PAX8)
09162 Cancer: specific types
05216 Thyroid cancer
7849 (PAX8)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
7849 (PAX8)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Helix-turn-helix
Homeo domain Paired-related
7849 (PAX8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PAX
Pax2_C
HTH_23
HTH_32
DUF6115
HTH_Tnp_IS1
Motif
Other DBs
NCBI-GeneID:
7849
NCBI-ProteinID:
NP_003457
OMIM:
167415
HGNC:
8622
Ensembl:
ENSG00000125618
UniProt:
Q06710
R9W7C9
Structure
PDB
LinkDB
All DBs
Position
2:complement(113215997..113278921)
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AA seq
450 aa
AA seq
DB search
MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD
PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL
LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP
NSSLLSSPYYYSSTSRPSAPPTTATAFDHL
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atgcctcacaactccatcagatctggccatggagggctgaaccagctgggaggggccttt
gtgaatggcagacctctgccggaagtggtccgccagcgcatcgtagacctggcccaccag
ggtgtaaggccctgcgacatctctcgccagctccgcgtcagccatggctgcgtcagcaag
atccttggcaggtactacgagactggcagcatccggcctggagtgatagggggctccaag
cccaaggtggccacccccaaggtggtggagaagattggggactacaaacgccagaaccct
accatgtttgcctgggagatccgagaccggctcctggctgagggcgtctgtgacaatgac
actgtgcccagtgtcagctccattaatagaatcatccggaccaaagtgcagcaaccattc
aacctccctatggacagctgcgtggccaccaagtccctgagtcccggacacacgctgatc
cccagctcagctgtaactcccccggagtcaccccagtcggattccctgggctccacctac
tccatcaatgggctcctgggcatcgctcagcctggcagcgacaagaggaaaatggatgac
agtgatcaggatagctgccgactaagcattgactcacagagcagcagcagcggaccccga
aagcaccttcgcacggatgccttcagccagcaccacctcgagccgctcgagtgcccattt
gagcggcagcactacccagaggcctatgcctcccccagccacaccaaaggcgagcagggc
ctctacccgctgcccttgctcaacagcaccctggacgacgggaaggccaccctgacccct
tccaacacgccactggggcgcaacctctcgactcaccagacctaccccgtggtggcagat
cctcactcacccttcgccataaagcaggaaacccccgaggtgtccagttctagctccacc
ccttcctctttatctagctccgcctttttggatctgcagcaagtcggctccggggtcccg
cccttcaatgcctttccccatgctgcctccgtgtacgggcagttcacgggccaggccctc
ctctcagggcgagagatggtggggcccacgctgcccggatacccaccccacatccccacc
agcggacagggcagctatgcctcctctgccatcgcaggcatggtggcaggaagtgaatac
tctggcaatgcctatggccacaccccctactcctcctacagcgaggcctggcgcttcccc
aactccagcttgctgagttccccatattattacagttccacatcaaggccgagtgcaccg
cccaccactgccacggcctttgaccatctgtag
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