| Entry |
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| Symbol |
MAD1L1, MAD1, MVA7, PIG9, TP53I9, TXBP181
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| Name |
(RefSeq) mitotic spindle assembly checkpoint protein MAD1 isoform a
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| KO |
| K06679 | mitotic spindle assembly checkpoint protein MAD1 |
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| Organism |
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| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
| hsa05166 | Human T-cell leukemia virus 1 infection |
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| Network |
nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06230 Cell cycle (cancer) nt06515 Regulation of kinetochore-microtubule interactions |
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| Element |
| N00222 | HTLV-1 Tax to spindle assembly checkpoint signaling |
| N00493 | Spindle assembly checkpoint signaling |
| N01529 | Recruitment and formation of the MCC |
| N01532 | Kinetochore targeting of MAD1-MAD2 |
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| Disease |
| H01288 | Mosaic variegated aneuploidy syndrome |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
8379 (MAD1L1)
04114 Oocyte meiosis
8379 (MAD1L1)
09150 Organismal Systems
09152 Endocrine system
04914 Progesterone-mediated oocyte maturation
8379 (MAD1L1)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
8379 (MAD1L1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
8379 (MAD1L1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:hsa03036]
8379 (MAD1L1)
Chromosome and associated proteins [BR:hsa03036]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Core SAC proteins
8379 (MAD1L1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
7:complement(1815795..2232945)
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| AA seq |
718 aa
MEDLGENTMVLSTLRSLNNFISQRVEGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRS
KSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQEREAGA
EEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRV
KRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAA
IVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETL
VGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSAR
GLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDS
ELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKML
KSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRT
KVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKE
VAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPG
DCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA |
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| NT seq |
2157 nt +upstreamnt +downstreamnt
atggaagacctgggggaaaacaccatggttttatccaccctgagatctttgaacaacttc
atctctcagcgtgtggagggaggctctggactggatatttctacctcggccccaggttct
ctgcagatgcagtaccagcagagcatgcagctggaggaaagagcagagcagatccgttcg
aagtcccacctcatccaggtggagcgggagaaaatgcagatggagctgagtcacaagagg
gctcgagtggagctggagagagcagccagcaccagtgccaggaactacgagcgtgaggtc
gaccgcaaccaggagctcctgacgcgcatccggcagcttcaggagcgggaggccggggcg
gaggagaagatgcaggagcagctggagcgcaacaggcagtgtcagcagaacttggatgct
gccagcaagaggctgcgtgagaaagaggacagtctggcccaggctggcgagaccatcaac
gcactgaaggggaggatctcggaactgcagtggagcgtgatggaccaggagatgcgggtg
aagcgcctggagtcggagaagcaggagctgcaggagcagctggacctgcaacacaaaaaa
tgccaggaagccaatcagaaaatccaggaactccaggccagccaagaagcaagagcagac
cacgagcagcagattaaggatctggagcagaagctgtccctgcaagagcaggatgcagcg
attgtgaagaacatgaagtctgagctggtacggctccctaggctggaacgggagctgaag
cagctgcgggaggagagcgcgcacctgcgggagatgagagagaccaacgggctgctccag
gaagagctggaagggctgcagaggaagctggggcgccaggagaagatgcaggagacgctg
gttggcttggagctggagaacgagaggctgctggccaagctgcaaagctgggagagactg
gaccagaccatgggcctgagcatcaggactccagaagacctttccagattcgtggttgag
ctgcagcagagggagcttgccttgaaggacaagaacagcgccgtcaccagcagcgcccgg
gggctggagaaggccaggcagcagctgcaggaggagctccggcaggtcagcggccagctg
ttggaggagaggaagaagcgcgagacccacgaggcgctggcccggaggctccagaaacgg
gtcctgctgctcaccaaggagcgggacggtatgcgggccatcctggggtcctacgacagc
gagctgaccccggccgagtactcaccccagctgacgcggcgcatgcgggaggctgaggat
atggtgcagaaggtgcacagccacagcgccgagatggaggctcagctgtcgcaggccctg
gaggagctgggaggccagaaacaaagagcagacatgctggagatggagctgaagatgctg
aagtctcagtccagctctgccgaacagagcttcctgttctccagggaggaggcggacacg
ctcaggttgaaggtcgaggagctggaaggcgagcggagtcggctggaggaggaaaagagg
atgctggaggcacagctggagcggcgagctctgcagggtgactatgaccagagcaggacc
aaagtgctgcacatgagcctgaaccccaccagtgtggccaggcagcgcctgcgcgaggac
cacagccagctgcaggcggagtgcgagcgactgcgcgggctcctgcgcgccatggagaga
ggaggcaccgtcccagccgaccttgaggctgccgccgcgagtctgccatcgtccaaggag
gtggcagagctgaagaagcaggtggagagtgccgagctgaagaaccagcggctcaaggag
gttttccagaccaagatccaggagttccgcaaggcctgctacacgctcaccggctaccag
atcgacatcaccacggagaaccagtaccggctgacctcgctgtacgccgagcacccaggc
gactgcctcatcttcaaggccaccagcccctcgggttccaagatgcagctactggagaca
gagttctcacacaccgtgggcgagctcatcgaggtgcacctgcggcgccaggacagcatc
cctgccttcctcagctcgctcaccctcgagctcttcagccgccagaccgtggcgtag |
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