Homo sapiens (human): 84699
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Entry
84699 CDS
T01001
Symbol
CREB3L3, CREB-H, CREBH, HYST1481, HYTG2
Name
(RefSeq) cAMP responsive element binding protein 3 like 3
KO
K09048
cyclic AMP-responsive element-binding protein 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04022
cGMP-PKG signaling pathway
hsa04024
cAMP signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa04152
AMPK signaling pathway
hsa04211
Longevity regulating pathway
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04668
TNF signaling pathway
hsa04714
Thermogenesis
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04911
Insulin secretion
hsa04915
Estrogen signaling pathway
hsa04916
Melanogenesis
hsa04918
Thyroid hormone synthesis
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04926
Relaxin signaling pathway
hsa04927
Cortisol synthesis and secretion
hsa04928
Parathyroid hormone synthesis, secretion and action
hsa04931
Insulin resistance
hsa04934
Cushing syndrome
hsa04935
Growth hormone synthesis, secretion and action
hsa04962
Vasopressin-regulated water reabsorption
hsa05016
Huntington disease
hsa05020
Prion disease
hsa05030
Cocaine addiction
hsa05031
Amphetamine addiction
hsa05034
Alcoholism
hsa05161
Hepatitis B
hsa05163
Human cytomegalovirus infection
hsa05165
Human papillomavirus infection
hsa05166
Human T-cell leukemia virus 1 infection
hsa05203
Viral carcinogenesis
hsa05207
Chemical carcinogenesis - receptor activation
hsa05215
Prostate cancer
Network
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06167
Human cytomegalovirus (HCMV)
nt06180
Pathogenic Escherichia coli
nt06210
ERK signaling (cancer)
nt06263
Hepatocellular carcinoma
nt06310
CRH-ACTH-cortisol signaling
nt06316
Renin-angiotensin-aldosterone signaling
nt06322
TRH-TSH-TH signaling
nt06324
GHRH-GH-IGF signaling
nt06360
Cushing syndrome
nt06461
Huntington disease
nt06465
Prion disease
nt06516
TNF signaling
Element
N00297
ACTH-cortisol signaling pathway
N00298
CYP11B1-CYP11B2 fusion to ACTH-cortisol signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N00320
Mutation-activated PRKACA to ACTH-cortisol signaling pathway
N00321
Mutation-activated GNAS to ACTH-cortisol signaling pathway
N00322
Mutation-inactivated PRKAR1A to ACTH-cortisol signaling pathway
N00323
Mutation-inactivated PDE11A/PDE8B to ACTH-cortisol signaling pathway
N00324
CRHR-PKA-ACTH signaling pathway
N00325
Mutation-inactivated RASD1 to CRHR-PKA-ACTH signaling pathway
N00326
Mutation-activated GNAS to CRHR-PKA-ACTH signaling pathway
N00327
Mutation-inactivated PRKAR1A to CRHR-PKA-ACTH signaling pathway
N00410
DRD1-GNAS-AC-PKA signaling pathway
N00444
TNF-p38 signaling pathway
N00544
HBV HBx to CREB-mediated transcription
N00782
TSH-TG signaling pathway
N00910
GHRHR-PKA-GH signaling pathway
N00981
Mutation-caused aberrant Htt to CREB-mediated transcription
N01204
PRNP-PI3K-NOX2 signaling pathway
N01343
ACH-CHRN-RAS-ERK signaling pathway
N01351
E2-ER-RAS-ERK signaling pathway
Disease
H01637
Hypertriglyceridemia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
84699 (CREB3L3)
04024 cAMP signaling pathway
84699 (CREB3L3)
04022 cGMP-PKG signaling pathway
84699 (CREB3L3)
04151 PI3K-Akt signaling pathway
84699 (CREB3L3)
04152 AMPK signaling pathway
84699 (CREB3L3)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
84699 (CREB3L3)
04922 Glucagon signaling pathway
84699 (CREB3L3)
04915 Estrogen signaling pathway
84699 (CREB3L3)
04926 Relaxin signaling pathway
84699 (CREB3L3)
04935 Growth hormone synthesis, secretion and action
84699 (CREB3L3)
04918 Thyroid hormone synthesis
84699 (CREB3L3)
04928 Parathyroid hormone synthesis, secretion and action
84699 (CREB3L3)
04916 Melanogenesis
84699 (CREB3L3)
04925 Aldosterone synthesis and secretion
84699 (CREB3L3)
04927 Cortisol synthesis and secretion
84699 (CREB3L3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
84699 (CREB3L3)
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
84699 (CREB3L3)
09156 Nervous system
04725 Cholinergic synapse
84699 (CREB3L3)
04728 Dopaminergic synapse
84699 (CREB3L3)
09149 Aging
04211 Longevity regulating pathway
84699 (CREB3L3)
09159 Environmental adaptation
04714 Thermogenesis
84699 (CREB3L3)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
84699 (CREB3L3)
05203 Viral carcinogenesis
84699 (CREB3L3)
09162 Cancer: specific types
05215 Prostate cancer
84699 (CREB3L3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
84699 (CREB3L3)
05161 Hepatitis B
84699 (CREB3L3)
05163 Human cytomegalovirus infection
84699 (CREB3L3)
05165 Human papillomavirus infection
84699 (CREB3L3)
09164 Neurodegenerative disease
05016 Huntington disease
84699 (CREB3L3)
05020 Prion disease
84699 (CREB3L3)
09165 Substance dependence
05030 Cocaine addiction
84699 (CREB3L3)
05031 Amphetamine addiction
84699 (CREB3L3)
05034 Alcoholism
84699 (CREB3L3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
84699 (CREB3L3)
04934 Cushing syndrome
84699 (CREB3L3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
84699 (CREB3L3)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Basic leucine zipper (bZIP)
CREB
84699 (CREB3L3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bZIP_1
bZIP_2
bZIP_Maf
ZapB
KASH_CCD
Mit_KHE1
pEK499_p136
OppC_N
DUF1664
Motif
Other DBs
NCBI-GeneID:
84699
NCBI-ProteinID:
NP_115996
OMIM:
611998
HGNC:
18855
Ensembl:
ENSG00000060566
UniProt:
Q68CJ9
LinkDB
All DBs
Position
19:4153631..4173054
Genome browser
AA seq
461 aa
AA seq
DB search
MNTDLAAGKMASAACSMDPIDSFELLDLLFDRQDGILRHVELGEGWGHVKDQQVLPNPDS
DDFLSSILGSGDSLPSSPLWSPEGSDSGISEDLPSDPQDTPPRSGPATSPAGCHPAQPGK
GPCLSYHPGNSCSTTTPGPVIQVPEASVTIDLEMWSPGGRICAEKPADPVDLSPRCNLTV
KDLLLSGSSGDLQQHHLGASYLLRPGAGHCQELVLTEDEKKLLAKEGITLPTQLPLTKYE
ERVLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNLSLL
EQLKKLQAIVVQSTSKSAQTGTCVAVLLLSFALIILPSISPFGPNKTESPGDFAPVRVFS
RTLHNDAASRVAADAVPGSEAPGPRPEADTTREESPGSPGADWGFQDTANLTNSTEELDN
ATLVLRNATEGLGQVALLDWVAPGPSTGSGRAGLEAAGDEL
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgaatacggatttagctgctggaaagatggcttctgctgcctgctccatggaccccatc
gacagctttgagctcctggatctcctgtttgaccggcaggacggcatcctgagacacgtg
gagctgggcgagggctggggtcacgtcaaggaccagcaggtcctgccaaaccccgactct
gacgacttcctcagctccatcctgggctctggagactcactgcccagctccccactctgg
tcccccgaaggcagtgatagtggcatctccgaagacctcccctccgacccccaggacacc
cctccacgcagcggaccagccacctcccccgccggctgccatcctgcccagcctggcaag
gggccctgcctctcctatcatcctggcaactcttgctccaccacaaccccagggccagtg
atccaagtacctgaagcctctgtgaccatagacctggaaatgtggagcccaggaggaagg
atctgtgctgagaagccggctgatccggtggacctgtccccacgatgcaatctcaccgtg
aaagacctcctcctttcgggcagcagtggggacctgcaacagcatcacctgggggcctcc
tacctcctgcgacctggggctgggcactgtcaggagctggtgctcaccgaggatgagaag
aagctgctggctaaagaaggcatcaccctgcccactcagctgcccctcactaagtacgag
gagcgagtgctgaaaaaaatccgccggaaaatccggaacaagcagtcggcgcaagaaagc
aggaagaagaagaaggaatatatcgatggcctggagactcggatgtcagcttgcactgct
cagaatcaggagttacagaggaaagtcttgcatctcgagaagcaaaacctgtccctcttg
gagcaactgaagaaactccaggccattgtggtgcagtccaccagcaagtcagcccagaca
ggcacctgtgtcgcagtcctgttgctgtcctttgccctcatcatcctcccctccatcagc
ccttttggccccaacaaaaccgagagccctggggactttgcgcctgtacgagtgttctcc
agaactttgcacaacgatgctgcctcccgcgtggctgctgatgctgtgccaggctccgag
gccccaggaccccgacccgaggctgacacaacccgagaagagtctccaggaagccccggg
gcagactggggcttccaggacaccgcgaacctgaccaattcgacggaggagctggacaac
gccaccctggtcctgaggaatgcaacagaggggctgggccaggtcgccctgctggactgg
gtggcgcctgggccgagcactggctcaggacgtgcagggctggaggcggcgggagacgag
ctgtga
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