Homo sapiens (human): 9586
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Entry
9586 CDS
T01001
Symbol
CREB5, CRE-BPA, CREB-5, CREBPA
Name
(RefSeq) cAMP responsive element binding protein 5
KO
K09047
cyclic AMP-responsive element-binding protein 5
Organism
hsa
Homo sapiens (human)
Pathway
hsa04022
cGMP-PKG signaling pathway
hsa04024
cAMP signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa04152
AMPK signaling pathway
hsa04211
Longevity regulating pathway
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04668
TNF signaling pathway
hsa04714
Thermogenesis
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04911
Insulin secretion
hsa04915
Estrogen signaling pathway
hsa04918
Thyroid hormone synthesis
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04926
Relaxin signaling pathway
hsa04927
Cortisol synthesis and secretion
hsa04928
Parathyroid hormone synthesis, secretion and action
hsa04931
Insulin resistance
hsa04934
Cushing syndrome
hsa04935
Growth hormone synthesis, secretion and action
hsa04962
Vasopressin-regulated water reabsorption
hsa05016
Huntington disease
hsa05020
Prion disease
hsa05030
Cocaine addiction
hsa05031
Amphetamine addiction
hsa05034
Alcoholism
hsa05161
Hepatitis B
hsa05163
Human cytomegalovirus infection
hsa05165
Human papillomavirus infection
hsa05166
Human T-cell leukemia virus 1 infection
hsa05203
Viral carcinogenesis
hsa05207
Chemical carcinogenesis - receptor activation
hsa05215
Prostate cancer
Network
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06167
Human cytomegalovirus (HCMV)
nt06180
Pathogenic Escherichia coli
nt06210
ERK signaling (cancer)
nt06263
Hepatocellular carcinoma
nt06310
CRH-ACTH-cortisol signaling
nt06316
Renin-angiotensin-aldosterone signaling
nt06322
TRH-TSH-TH signaling
nt06324
GHRH-GH-IGF signaling
nt06360
Cushing syndrome
nt06461
Huntington disease
nt06465
Prion disease
nt06516
TNF signaling
Element
N00297
ACTH-cortisol signaling pathway
N00298
CYP11B1-CYP11B2 fusion to ACTH-cortisol signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N00320
Mutation-activated PRKACA to ACTH-cortisol signaling pathway
N00321
Mutation-activated GNAS to ACTH-cortisol signaling pathway
N00322
Mutation-inactivated PRKAR1A to ACTH-cortisol signaling pathway
N00323
Mutation-inactivated PDE11A/PDE8B to ACTH-cortisol signaling pathway
N00324
CRHR-PKA-ACTH signaling pathway
N00325
Mutation-inactivated RASD1 to CRHR-PKA-ACTH signaling pathway
N00326
Mutation-activated GNAS to CRHR-PKA-ACTH signaling pathway
N00327
Mutation-inactivated PRKAR1A to CRHR-PKA-ACTH signaling pathway
N00410
DRD1-GNAS-AC-PKA signaling pathway
N00444
TNF-p38 signaling pathway
N00544
HBV HBx to CREB-mediated transcription
N00782
TSH-TG signaling pathway
N00910
GHRHR-PKA-GH signaling pathway
N00981
Mutation-caused aberrant Htt to CREB-mediated transcription
N01204
PRNP-PI3K-NOX2 signaling pathway
N01343
ACH-CHRN-RAS-ERK signaling pathway
N01351
E2-ER-RAS-ERK signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
9586 (CREB5)
04024 cAMP signaling pathway
9586 (CREB5)
04022 cGMP-PKG signaling pathway
9586 (CREB5)
04151 PI3K-Akt signaling pathway
9586 (CREB5)
04152 AMPK signaling pathway
9586 (CREB5)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
9586 (CREB5)
04922 Glucagon signaling pathway
9586 (CREB5)
04915 Estrogen signaling pathway
9586 (CREB5)
04926 Relaxin signaling pathway
9586 (CREB5)
04935 Growth hormone synthesis, secretion and action
9586 (CREB5)
04918 Thyroid hormone synthesis
9586 (CREB5)
04928 Parathyroid hormone synthesis, secretion and action
9586 (CREB5)
04925 Aldosterone synthesis and secretion
9586 (CREB5)
04927 Cortisol synthesis and secretion
9586 (CREB5)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
9586 (CREB5)
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
9586 (CREB5)
09156 Nervous system
04725 Cholinergic synapse
9586 (CREB5)
04728 Dopaminergic synapse
9586 (CREB5)
09149 Aging
04211 Longevity regulating pathway
9586 (CREB5)
09159 Environmental adaptation
04714 Thermogenesis
9586 (CREB5)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
9586 (CREB5)
05203 Viral carcinogenesis
9586 (CREB5)
09162 Cancer: specific types
05215 Prostate cancer
9586 (CREB5)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
9586 (CREB5)
05161 Hepatitis B
9586 (CREB5)
05163 Human cytomegalovirus infection
9586 (CREB5)
05165 Human papillomavirus infection
9586 (CREB5)
09164 Neurodegenerative disease
05016 Huntington disease
9586 (CREB5)
05020 Prion disease
9586 (CREB5)
09165 Substance dependence
05030 Cocaine addiction
9586 (CREB5)
05031 Amphetamine addiction
9586 (CREB5)
05034 Alcoholism
9586 (CREB5)
09167 Endocrine and metabolic disease
04931 Insulin resistance
9586 (CREB5)
04934 Cushing syndrome
9586 (CREB5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
9586 (CREB5)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Basic leucine zipper (bZIP)
AP-1(-like) components, CRE-BP/ATF
9586 (CREB5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bZIP_1
bZIP_2
bZIP_Maf
TolA_bind_tri
ZapB
NDUFB11
DUF3874
DUF6262
Motif
Other DBs
NCBI-GeneID:
9586
NCBI-ProteinID:
NP_878901
OMIM:
618262
HGNC:
16844
Ensembl:
ENSG00000146592
UniProt:
Q02930
LinkDB
All DBs
Position
7:28299321..28825894
Genome browser
AA seq
508 aa
AA seq
DB search
MIYEESKMNLEQERPFVCSAPGCSQRFPTEDHLMIHRHKHEMTLKFPSIKTDNMLSDQTP
TPTRFLKNCEEVGLFSELDCSLEHEFRKAQEEESSKRNISMHNAVGGAMTGPGTHQLSSA
RLPNHDTNVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMPASMP
GTLPNPTMPGSSAVLMPMERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAAL
THHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHH
PHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQ
PTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNE
VSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQQQVIQHNTIT
TSSSVSEVVGSSTLSQLTTHRTDLNPIL
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgatttatgaggaatccaagatgaatttggagcaggagaggccgtttgtctgcagtgcc
ccaggctgctcccagcgcttcccaacagaggaccatctgatgattcataggcacaaacat
gaaatgactttgaagtttccttcaataaaaacagacaatatgttatcagatcaaactccg
accccaacgagattcctgaagaactgcgaggaggtgggcctcttcagcgagctggactgc
tccctggagcacgagttcaggaaggctcaggaagaggagagcagcaagcggaatatctcg
atgcataatgcagttggtggggccatgacggggcccggaactcaccagcttagcagcgct
cggctgcccaaccatgacaccaacgttgtgattcagcaagccatgccgtcgcctcagtcc
agctctgtcatcactcaggcaccttccaccaaccgccagatcgggcctgtcccaggctct
ctatcttctctgctacatctccacaacagacagagacagcccatgccagcctccatgcct
gggaccctgcccaaccctacaatgccaggatcttccgccgtcttgatgccaatggagcga
caaatgtcagtgaactccagcatcatggggatgcaaggtccaaatctcagcaacccctgt
gcttctccccaggtccagccaatgcattcagaagccaaaatgaggttgaaggctgcattg
actcaccaccctgctgccatgtcaaatgggaacatgaacaccatgggacacatgatggag
atgatgggctcccggcaggaccagacgccacaccatcacatgcactcgcacccgcatcag
caccagacactgccaccccatcacccttacccacaccagcaccagcacccagcacaccat
cctcaccctcaaccccatcaccagcagaaccatccacatcaccactcccattcccacctt
catgcacacccagcacatcaccagacctcgccacatccgcccctgcacaccggcaaccaa
gcacaggtttcaccagcaacacaacagatgcagccaacccagacaatacagccaccccag
cccacaggggggcgccggcgaagggtggtagacgaggatccggacgagaggcggcggaaa
tttctggaacggaaccgggcagctgccacccgctgcagacagaagaggaaggtctgggtg
atgtcattggaaaagaaagcagaagaactcacccagacaaacatgcagcttcagaatgaa
gtgtctatgttgaaaaatgaggtggcccagctgaaacagttgttgttaacacataaagac
tgcccaataacagccatgcagaaagaatcacaaggatatctaagtccagagagtagccct
cctgctagtcctgtcccagcttgctcccagcaacaagtcatccagcataataccatcact
acttcctcatcggtcagcgaggtggtaggaagctccaccctcagccagctcaccactcac
agaacagacctgaatccgattctttaa
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