KEGG PATHWAY: lma00564

PATHWAY: lma00564

Entry

lma00564                    Pathway

Name

Glycerophospholipid metabolism - Leishmania major

Class

Metabolism; Lipid metabolism

Pathway map

lma00564

Glycerophospholipid metabolism

Module

lma_M00091

Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:lma00564]

Other DBs

GO:

0006650

Organism

Leishmania major [GN:lma]

Gene

LMJF_10_0510

GPD; glycerol-3-phosphate dehydrogenase [NAD+],glycosomal [KO:K00006] [EC:1.1.1.8]

LMJF_20_0430

glycerol-3-phosphate dehydrogenase-like protein [KO:K00111] [EC:1.1.5.3]

LMJF_28_0240

glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial [KO:K00111] [EC:1.1.5.3]

LMJF_03_0080

GAT; glycerol-3-phosphate acyl transferase [KO:K13507] [EC:2.3.1.15 2.3.1.42]

LMJF_34_1090

DAT; dihydroxyacetonephosphate acyltransferase [KO:K00649] [EC:2.3.1.42]

LMJF_18_0440

putative phosphatidic acid phosphatase [KO:K01080] [EC:3.1.3.4]

LMJF_06_0830

putative lipin [KO:K15728] [EC:3.1.3.4]

LMJF_35_5370

diacylglycerol kinase-like protein [KO:K00901] [EC:2.7.1.107]

LMJF_24_1840

putative lysophospholipase [KO:K06128] [EC:3.1.1.5]

LMJF_36_5960

putative glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]

LMJF_36_5900

putative choline/ethanolamine phosphotransferase (CEPT) [KO:K00993] [EC:2.7.8.1]

LMJF_32_0890

putative ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]

LMJF_31_2290

phosphatidylethanolaminen-methyltransferase-lik E protein [KO:K00551] [EC:2.1.1.17 2.1.1.71]

LMJF_31_3120

phosphatidylethanolaminen-methyltransferase-lik E protein [KO:K16369] [EC:2.1.1.17]

LMJF_26_1620

cdp-diacylglycerol synthetase-like protein [KO:K00981] [EC:2.7.7.41]

LMJF_35_4590

putative phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]

LMJF_07_0200

putative phosphatidylglycerophosphate synthase [KO:K00995] [EC:2.7.8.5]

LMJF_26_2480

putative phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]

Compound

C00040

Acyl-CoA

C00065

L-Serine

C00084

Acetaldehyde

C00093

sn-Glycerol 3-phosphate

C00111

Glycerone phosphate

C00114

Choline

C00157

Phosphatidylcholine

C00189

Ethanolamine

C00269

CDP-diacylglycerol

C00307

CDP-choline

C00344

Phosphatidylglycerol

C00346

Ethanolamine phosphate

C00350

Phosphatidylethanolamine

C00416

Phosphatidate

C00513

CDP-glycerol

C00570

CDP-ethanolamine

C00588

Choline phosphate

C00623

sn-Glycerol 1-phosphate

C00641

1,2-Diacyl-sn-glycerol

C00670

sn-Glycero-3-phosphocholine

C00681

1-Acyl-sn-glycerol 3-phosphate

C01194

1-Phosphatidyl-D-myo-inositol

C01210

N-Methylethanolamine phosphate

C01233

sn-Glycero-3-phosphoethanolamine

C01241

Phosphatidyl-N-methylethanolamine

C01996

Acetylcholine

C02737

Phosphatidylserine

C03372

Acylglycerone phosphate

C03819

1-Acylglycerophosphoinositol

C03872

L-Serine-phosphoethanolamine

C03892

Phosphatidylglycerophosphate

C03974

2-Acyl-sn-glycerol 3-phosphate

C04230

1-Acyl-sn-glycero-3-phosphocholine

C04233

2-Acyl-sn-glycero-3-phosphocholine

C04308

Phosphatidyl-N-dimethylethanolamine

C04438

1-Acyl-sn-glycero-3-phosphoethanolamine

C04590

3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate

C04638

2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate

C05973

2-Acyl-sn-glycero-3-phosphoethanolamine

C05974

2-Acyl-sn-glycero-3-phosphoserine

C05976

Aminoacyl-phosphatidylglycerol

C05980

Cardiolipin

C06771

Triethanolamine

C06772

Diethanolamine

C13482

Phosphodimethylethanolamine

C18059

CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol

C18125

1-Acyl-sn-glycero-3-phosphoserine

C18126

1-Acyl-sn-glycero-3-phosphoglycerol

C18129

Monolysocardiolipin

C18168

Diacylglycerylhomoserine

C18169

Diacylglyceryl-N,N,N-trimethylhomoserine

C20466

2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine

C20518

2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate

C22340

Heptaprenylglyceryl phosphate

C22341

Heptaprenylglycerol

C22342

Diacetylheptaprenylglycerol

Reference

PMID:1512203

Authors

Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.

Title

The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.

Journal

J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992

Reference

PMID:10092508

Authors

Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.

Title

Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

Journal

Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411

Reference

PMID:10542045

Authors

Athenstaedt K, Daum G.

Title

Phosphatidic acid, a key intermediate in lipid metabolism.

Journal

Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x

Reference

PMID:12431977

Authors

Shields DJ, Lehner R, Agellon LB, Vance DE.

Title

Membrane topography of human phosphatidylethanolamine N-methyltransferase.

Journal

J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200

Reference

PMID:14663079

Authors

Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.

Title

Pathways for phosphatidylcholine biosynthesis in bacteria.

Journal

Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0

Reference

PMID:15522832

Authors

Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.

Title

Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.

Journal

Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007

Reference

PMID:1649829

Authors

Hsu L, Jackowski S, Rock CO

Title

Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.

Journal

J Biol Chem 266:13783-8 (1991)

Reference

PMID:10938271

Authors

Stone SJ, Vance JE.

Title

Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.

Journal

J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200

Related
pathway

lma00010