Entry |
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Symbol |
LPIN
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Name |
phosphatidate phosphatase LPIN [EC: 3.1.3.4]
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Pathway |
map01110 | Biosynthesis of secondary metabolites |
|
Module |
M00089 | Triacylglycerol biosynthesis |
|
Reaction |
R02239 | 1,2-diacyl-sn-glycerol 3-phosphate phosphohydrolase |
|
Disease |
H01117 | Chronic recurrent multifocal osteomyelitis |
H01290 | Acute recurrent myoglobinuria |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09103 Lipid metabolism
00561 Glycerolipid metabolism
K15728 LPIN; phosphatidate phosphatase LPIN
00564 Glycerophospholipid metabolism
K15728 LPIN; phosphatidate phosphatase LPIN
09130 Environmental Information Processing
09132 Signal transduction
04150 mTOR signaling pathway
K15728 LPIN; phosphatidate phosphatase LPIN
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
K15728 LPIN; phosphatidate phosphatase LPIN
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins
K15728 LPIN; phosphatidate phosphatase LPIN
Enzymes [BR:ko01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.4 phosphatidate phosphatase
K15728 LPIN; phosphatidate phosphatase LPIN
Protein phosphatases and associated proteins [BR:ko01009]
HAD phosphatases
Other HAD phosphatases
K15728 LPIN; phosphatidate phosphatase LPIN
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Other DBs |
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Genes |
» show all
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Reference |
|
Authors |
Donkor J, Sariahmetoglu M, Dewald J, Brindley DN, Reue K |
Title |
Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns. |
Journal |
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Reference |
|
Authors |
Santos-Rosa H, Leung J, Grimsey N, Peak-Chew S, Siniossoglou S |
Title |
The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth. |
Journal |
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Sequence |
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Reference |
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Authors |
Huffman TA, Mothe-Satney I, Lawrence JC Jr |
Title |
Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin. |
Journal |
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Sequence |
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LinkDB |
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