KEGG   MODULE: M00026
Entry
M00026            Pathway   Module                                 
Name
Histidine biosynthesis, PRPP => histidine
Definition
(K00765-K02502) (K01523 K01496,K11755,K14152) (K01814,K24017) (K02501+K02500,K01663) ((K01693 K00817 (K04486,K05602,K18649)),(K01089 K00817)) (K00013,K14152)
Diagram
M00026

Orthology
K00765,K02502  
ATP phosphoribosyltransferase [EC:2.4.2.17] [RN:R01071]
K01523,K11755,K14152  
phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] [RN:R04035]
K01496,K11755,K14152  
phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] [RN:R04037]
K01814,K24017  
phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] [RN:R04640]
K02500,K02501,K01663  
imidazole glycerol-phosphate synthase [EC:4.3.2.10] [RN:R04558]
K01693  
imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] [RN:R03457]
K00817  
histidinol-phosphate aminotransferase [EC:2.6.1.9] [RN:R03243]
K04486,K05602,K18649  
histidinol-phosphatase [EC:3.1.3.15] [RN:R03013]
K01089  
imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15] [RN:R03457 R03013]
K00013,K14152  
histidinol dehydrogenase [EC:1.1.1.23] [RN:R03012 R01163]
Class
Pathway modules; Amino acid metabolism; Histidine metabolism
Pathway
map00340  Histidine metabolism
map01230  Biosynthesis of amino acids
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R01071  
R04035  
R04037  
R04640  
R04558  
R03457  
R03243  
R03013  
R03012  
R01163  
Compound
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C02739  1-(5-Phospho-D-ribosyl)-ATP
C02741  Phosphoribosyl-AMP
C04896  5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
C04916  N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide
C04666  D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate
C01267  3-(Imidazol-4-yl)-2-oxopropyl phosphate
C01100  L-Histidinol phosphate
C00860  L-Histidinol
C01929  L-Histidinal
C00135  L-Histidine
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