KEGG   PATHWAY: abri00630
Entry
abri00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Acidianus brierleyi
Class
Metabolism; Carbohydrate metabolism
Pathway map
abri00630  Glyoxylate and dicarboxylate metabolism
abri00630

Module
abri_M00621  Glycine cleavage system [PATH:abri00630]
abri_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:abri00630]
Other DBs
GO: 0046487 0043648
Organism
Acidianus brierleyi [GN:abri]
Gene
DFR85_15465  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
DFR85_15645  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
DFR85_12015  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
DFR85_13850  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
DFR85_14670  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
DFR85_14940  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DFR85_14975  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
DFR85_06225  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DFR85_14910  malate synthase [KO:K01638] [EC:2.3.3.9]
DFR85_15840  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DFR85_15820  citrate synthase [KO:K01647] [EC:2.3.3.1]
DFR85_05845  citrate synthase [KO:K01647] [EC:2.3.3.1]
DFR85_11915  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
DFR85_15390  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DFR85_13830  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DFR85_13835  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DFR85_00610  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DFR85_14625  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DFR85_10215  thiolase family protein [KO:K00626] [EC:2.3.1.9]
DFR85_15335  thiolase family protein [KO:K00626] [EC:2.3.1.9]
DFR85_00820  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DFR85_05890  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01964] [EC:6.4.1.2 6.4.1.3]
DFR85_05880  methylmalonyl-CoA carboxyltransferase [KO:K15036] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
DFR85_05885  biotin/lipoyl-binding protein [KO:K15037]
DFR85_08400  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
DFR85_00815  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
DFR85_11475  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DFR85_14875  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DFR85_02765  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DFR85_14870  4Fe-4S dicluster domain-containing protein [KO:K11473] [EC:1.1.99.14]
DFR85_06265  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
DFR85_08745  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
DFR85_01465  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
DFR85_02815  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DFR85_12500  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DFR85_00905  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DFR85_10055  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DFR85_10230  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
DFR85_10440  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
DFR85_10445  aminotransferase class V-fold PLP-dependent enzyme [KO:K00283] [EC:1.4.4.2]
DFR85_10435  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DFR85_02120  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DFR85_11405  pyridine nucleotide-disulfide oxidoreductase [KO:K00382] [EC:1.8.1.4]
DFR85_09125  NAD(P)-binding protein [KO:K00382] [EC:1.8.1.4]
DFR85_09320  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DFR85_11815  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DFR85_10430  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DFR85_12780  glycine cleavage system protein H [KO:K02437]
DFR85_09105  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
DFR85_02160  aldehyde dehydrogenase family protein [KO:K07248] [EC:1.2.1.22 1.2.1.21]
DFR85_12955  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
DFR85_12970  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
DFR85_13965  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
DFR85_13550  cyclase family protein [KO:K07130] [EC:3.5.1.9]
DFR85_12570  cyclase family protein [KO:K07130] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
abri00010  Glycolysis / Gluconeogenesis
abri00020  Citrate cycle (TCA cycle)
abri00030  Pentose phosphate pathway
abri00053  Ascorbate and aldarate metabolism
abri00071  Fatty acid degradation
abri00230  Purine metabolism
abri00250  Alanine, aspartate and glutamate metabolism
abri00260  Glycine, serine and threonine metabolism
abri00620  Pyruvate metabolism
abri00710  Carbon fixation by Calvin cycle
abri00750  Vitamin B6 metabolism
abri00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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