KEGG   PATHWAY: acut00630
Entry
acut00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Acuticoccus sp. I52.16.1
Class
Metabolism; Carbohydrate metabolism
Pathway map
acut00630  Glyoxylate and dicarboxylate metabolism
acut00630

Module
acut_M00012  Glyoxylate cycle [PATH:acut00630]
acut_M00621  Glycine cleavage system [PATH:acut00630]
acut_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:acut00630]
Other DBs
GO: 0046487 0043648
Organism
Acuticoccus sp. I52.16.1 [GN:acut]
Gene
MRB58_08355  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MRB58_18195  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MRB58_00580  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
MRB58_24545  malate synthase G [KO:K01638] [EC:2.3.3.9]
MRB58_10070  hypothetical protein [KO:K01638] [EC:2.3.3.9]
MRB58_16460  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MRB58_00880  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
MRB58_16405  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
MRB58_00545  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MRB58_02760  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MRB58_07895  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MRB58_14230  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
MRB58_07905  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
MRB58_20705  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MRB58_00795  acyl-CoA dehydrogenase family protein [KO:K14448] [EC:1.3.8.12]
MRB58_17735  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
MRB58_10350  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
MRB58_17765  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
MRB58_10345  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
MRB58_04625  methylmalonyl-CoA mutase family protein [KO:K01847] [EC:5.4.99.2]
MRB58_04630  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
MRB58_17940  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
MRB58_17930  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
MRB58_17920  heterodisulfide reductase-related iron-sulfur binding cluster [KO:K11473] [EC:1.1.99.14]
MRB58_15560  catalase [KO:K03781] [EC:1.11.1.6]
MRB58_07115  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
MRB58_02875  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
MRB58_14040  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
MRB58_22005  D-2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
MRB58_12010  D-2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
MRB58_16835  D-2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
MRB58_17630  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
MRB58_17775  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
MRB58_20745  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
MRB58_18345  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
MRB58_18935  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MRB58_22150  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MRB58_08505  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MRB58_09765  hypothetical protein [KO:K01915] [EC:6.3.1.2]
MRB58_13665  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MRB58_18420  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MRB58_00720  gcvPA; aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
MRB58_00715  gcvPB; aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
MRB58_00740  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
MRB58_03530  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MRB58_07670  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MRB58_15805  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MRB58_16310  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MRB58_00735  gcvH; glycine cleavage system protein GcvH [KO:K02437]
MRB58_06030  NAD(P)-dependent oxidoreductase [KO:K00042] [EC:1.1.1.60]
MRB58_17365  glycerate kinase [KO:K00865] [EC:2.7.1.165]
MRB58_24220  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
MRB58_03395  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
MRB58_04455  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
MRB58_04450  NAD(P)H-dependent oxidoreductase subunit E [KO:K22515] [EC:1.17.1.9]
MRB58_03390  fdh3B; formate dehydrogenase FDH3 subunit beta [KO:K00124]
MRB58_03385  formate dehydrogenase subunit gamma [KO:K00127]
MRB58_01010  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
MRB58_17175  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
acut00010  Glycolysis / Gluconeogenesis
acut00020  Citrate cycle (TCA cycle)
acut00030  Pentose phosphate pathway
acut00053  Ascorbate and aldarate metabolism
acut00071  Fatty acid degradation
acut00230  Purine metabolism
acut00250  Alanine, aspartate and glutamate metabolism
acut00260  Glycine, serine and threonine metabolism
acut00620  Pyruvate metabolism
acut00710  Carbon fixation by Calvin cycle
acut00750  Vitamin B6 metabolism
acut00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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