KEGG   PATHWAY: axn00630
Entry
axn00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Achromobacter xylosoxidans NBRC 15126 = ATCC 27061
Class
Metabolism; Carbohydrate metabolism
Pathway map
axn00630  Glyoxylate and dicarboxylate metabolism
axn00630

Module
axn_M00012  Glyoxylate cycle [PATH:axn00630]
axn_M00621  Glycine cleavage system [PATH:axn00630]
Other DBs
GO: 0046487 0043648
Organism
Achromobacter xylosoxidans NBRC 15126 = ATCC 27061 [GN:axn]
Gene
AX27061_4595  Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
AX27061_2202  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
AX27061_1493  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
AX27061_1523  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
AX27061_5949  Malate synthase G [KO:K01638] [EC:2.3.3.9]
AX27061_1534  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
AX27061_1541  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
AX27061_3252  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
AX27061_5481  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
AX27061_5651  putative Citrate synthase [KO:K01647] [EC:2.3.3.1]
AX27061_4284  Aconitate hydratase / 2-methylisocitrate dehydratase [KO:K01681] [EC:4.2.1.3]
AX27061_5113  Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
AX27061_4706  Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
AX27061_4634  3-ketoacyl-CoA thiolase / Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AX27061_4354  3-ketoacyl-CoA thiolase / Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AX27061_4084  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
AX27061_4091  Acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
AX27061_3311  3-ketoacyl-CoA thiolase / Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AX27061_2310  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
AX27061_0119  Acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
AX27061_0112  Thiolase [KO:K00626] [EC:2.3.1.9]
AX27061_1571  Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
AX27061_5428  Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
AX27061_1329  Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
AX27061_1792  Glycolate dehydrogenase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
AX27061_1793  Glycolate dehydrogenase, FAD-binding subunit GlcE [KO:K11472] [EC:1.1.99.14]
AX27061_1794  Glycolate dehydrogenase, iron-sulfur subunit GlcF [KO:K11473] [EC:1.1.99.14]
AX27061_6077  Catalase [KO:K03781] [EC:1.11.1.6]
AX27061_4152  Catalase [KO:K03781] [EC:1.11.1.6]
AX27061_0031  D-3-phosphoglycerate dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
AX27061_0785  D-3-phosphoglycerate dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
AX27061_5728  putative haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
AX27061_0370  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
AX27061_1447  putative phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
AX27061_6039  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
AX27061_0693  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AX27061_5390  Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) [KO:K00281] [EC:1.4.4.2]
AX27061_5392  Aminomethyltransferase (glycine cleavage system T protein) [KO:K00605] [EC:2.1.2.10]
AX27061_1554  Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase [KO:K00382] [EC:1.8.1.4]
AX27061_5604  Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex [KO:K00382] [EC:1.8.1.4]
AX27061_2361  Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase [KO:K00382] [EC:1.8.1.4]
AX27061_2412  Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex [KO:K00382] [EC:1.8.1.4]
AX27061_2652  Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
AX27061_5391  Glycine cleavage system H protein [KO:K02437]
AX27061_0884  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
AX27061_4599  Tartrate dehydrogenase / Tartrate decarboxylase / D-malic enzyme [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
AX27061_1926  Tartrate dehydrogenase / Tartrate decarboxylase / D-malic enzyme [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
AX27061_0973  4-Hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
AX27061_4993  NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
AX27061_4991  NAD-dependent formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
AX27061_0346  Formate dehydrogenase O alpha subunit [KO:K00123] [EC:1.17.1.9]
AX27061_4990  NAD-dependent formate dehydrogenase beta subunit [KO:K00124]
AX27061_0347  Formate dehydrogenase O beta subunit [KO:K00124]
AX27061_4989  NAD-dependent formate dehydrogenase gamma subunit [KO:K00127]
AX27061_0348  Formate dehydrogenase O gamma subunit [KO:K00127]
AX27061_0463  hypothetical protein [KO:K01432] [EC:3.5.1.9]
AX27061_4148  esterase/lipase/thioesterase family protein [KO:K01432] [EC:3.5.1.9]
AX27061_1669  Kynurenine formamidase, bacterial [KO:K07130] [EC:3.5.1.9]
AX27061_0949  Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
AX27061_3993  Formamidase [KO:K01455] [EC:3.5.1.49]
AX27061_2323  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
axn00010  Glycolysis / Gluconeogenesis
axn00020  Citrate cycle (TCA cycle)
axn00030  Pentose phosphate pathway
axn00053  Ascorbate and aldarate metabolism
axn00071  Fatty acid degradation
axn00230  Purine metabolism
axn00250  Alanine, aspartate and glutamate metabolism
axn00260  Glycine, serine and threonine metabolism
axn00620  Pyruvate metabolism
axn00710  Carbon fixation by Calvin cycle
axn00750  Vitamin B6 metabolism
axn00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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