KEGG   PATHWAY: bcan02020
Entry
bcan02020                   Pathway                                
Name
Two-component system - Bradyrhizobium canariense
Description
Two-component signal transduction systems enable bacteria to sense, respond, and adapt to changes in their environment or in their intracellular state. Each two-component system consists of a sensor protein-histidine kinase (HK) and a response regulator (RR). In the prototypical two-component pathway, the sensor HK phosphorylates its own conserved His residue in response to a signal(s) in the environment. Subsequently, the phosphoryl group of HK is transferred onto a specific Asp residue on the RR. The activated RR can then effect changes in cellular physiology, often by regulating gene expression. Two-component pathways thus often enable cells to sense and respond to stimuli by inducing changes in transcription.
Class
Environmental Information Processing; Signal transduction
Pathway map
bcan02020  Two-component system
bcan02020

Other DBs
GO: 0000160
Organism
Bradyrhizobium canariense [GN:bcan]
Gene
BcanWSM471_35395  two-component sensor histidine kinase [KO:K07636] [EC:2.7.13.3]
BcanWSM471_35365  phoB; phosphate regulon transcriptional regulator PhoB [KO:K07657]
BcanWSM471_01670  alkaline phosphatase D family protein [KO:K01113] [EC:3.1.3.1]
BcanWSM471_12215  alkaline phosphatase D family protein [KO:K01113] [EC:3.1.3.1]
BcanWSM471_35390  pstS; phosphate ABC transporter substrate-binding protein PstS [KO:K02040]
BcanWSM471_32795  two-component sensor histidine kinase [KO:K07638] [EC:2.7.13.3]
BcanWSM471_32790  response regulator transcription factor [KO:K07659]
BcanWSM471_28510  Do family serine endopeptidase [KO:K04771] [EC:3.4.21.107]
BcanWSM471_12060  Do family serine endopeptidase [KO:K04771] [EC:3.4.21.107]
BcanWSM471_14945  Do family serine endopeptidase [KO:K04771] [EC:3.4.21.107]
BcanWSM471_33490  ATP-binding protein [KO:K07641] [EC:2.7.13.3]
BcanWSM471_20015  efflux RND transporter periplasmic adaptor subunit [KO:K07799]
BcanWSM471_16875  efflux RND transporter periplasmic adaptor subunit [KO:K07799]
BcanWSM471_20020  efflux RND transporter permease subunit [KO:K07788]
BcanWSM471_20025  efflux RND transporter permease subunit [KO:K07789]
BcanWSM471_25930  DUF1522 domain-containing protein [KO:K02406]
BcanWSM471_25935  DUF1522 domain-containing protein [KO:K02406]
BcanWSM471_25940  DUF1522 domain-containing protein [KO:K02406]
BcanWSM471_25945  DUF1522 domain-containing protein [KO:K02406]
BcanWSM471_30235  flagellin [KO:K02406]
BcanWSM471_30240  flagellin [KO:K02406]
BcanWSM471_30320  motA; flagellar motor stator protein MotA [KO:K02556]
BcanWSM471_16430  MotA/TolQ/ExbB proton channel family protein [KO:K02556]
BcanWSM471_29910  sensor histidine kinase KdpD [KO:K07646] [EC:2.7.13.3]
BcanWSM471_29905  response regulator transcription factor [KO:K07667]
BcanWSM471_29925  kdpA; potassium-transporting ATPase subunit KdpA [KO:K01546]
BcanWSM471_29920  kdpB; potassium-transporting ATPase subunit KdpB [KO:K01547] [EC:7.2.2.6]
BcanWSM471_29915  K(+)-transporting ATPase subunit C [KO:K01548]
BcanWSM471_10970  response regulator [KO:K07772]
BcanWSM471_26705  tripartite tricarboxylate transporter permease [KO:K07793]
BcanWSM471_28545  tripartite tricarboxylate transporter permease [KO:K07793]
BcanWSM471_19165  tripartite tricarboxylate transporter permease [KO:K07793]
BcanWSM471_26710  tripartite tricarboxylate transporter TctB family protein [KO:K07794]
BcanWSM471_14535  tripartite tricarboxylate transporter TctB family protein [KO:K07794]
BcanWSM471_28550  tripartite tricarboxylate transporter TctB family protein [KO:K07794]
BcanWSM471_26715  tripartite tricarboxylate transporter substrate binding protein [KO:K07795]
BcanWSM471_30810  tripartite tricarboxylate transporter substrate binding protein [KO:K07795]
BcanWSM471_14540  tripartite tricarboxylate transporter substrate binding protein [KO:K07795]
BcanWSM471_19155  tripartite tricarboxylate transporter substrate binding protein [KO:K07795]
BcanWSM471_22195  COX15/CtaA family protein [KO:K02259] [EC:1.17.99.9]
BcanWSM471_00005  dnaA; chromosomal replication initiator protein DnaA [KO:K02313]
BcanWSM471_04765  sensor histidine kinase [KO:K14980] [EC:2.7.13.3]
BcanWSM471_04770  response regulator transcription factor [KO:K14981]
BcanWSM471_22720  M15 family metallopeptidase [KO:K08641] [EC:3.4.13.22]
BcanWSM471_29960  CoA ester lyase [KO:K01644] [EC:4.1.3.34]
BcanWSM471_01840  CoA ester lyase [KO:K01644] [EC:4.1.3.34]
BcanWSM471_08770  CoA ester lyase [KO:K01644] [EC:4.1.3.34]
BcanWSM471_27425  histidine kinase [KO:K07675] [EC:2.7.13.3]
BcanWSM471_23340  response regulator transcription factor [KO:K07689]
BcanWSM471_25230  response regulator transcription factor [KO:K07689]
BcanWSM471_27430  response regulator transcription factor [KO:K07689]
BcanWSM471_23410  serine hydrolase [KO:K01467] [EC:3.5.2.6]
BcanWSM471_09410  fatty acid desaturase [KO:K10255] [EC:1.14.19.23 1.14.19.45]
BcanWSM471_28965  Flp family type IVb pilin [KO:K02651]
BcanWSM471_31155  Flp family type IVb pilin [KO:K02651]
BcanWSM471_06005  Flp family type IVb pilin [KO:K02651]
BcanWSM471_14875  Flp family type IVb pilin [KO:K02651]
BcanWSM471_17780  Flp family type IVb pilin [KO:K02651]
BcanWSM471_18495  Flp family type IVb pilin [KO:K02651]
BcanWSM471_01035  cpaB; Flp pilus assembly protein CpaB [KO:K02279]
BcanWSM471_05990  cpaB; Flp pilus assembly protein CpaB [KO:K02279]
BcanWSM471_01040  type II and III secretion system protein family protein [KO:K02280]
BcanWSM471_05985  type II and III secretion system protein family protein [KO:K02280]
BcanWSM471_01050  AAA family ATPase [KO:K02282]
BcanWSM471_05975  AAA family ATPase [KO:K02282]
BcanWSM471_05970  CpaF family protein [KO:K02283] [EC:7.4.2.8]
BcanWSM471_05965  type II secretion system F family protein [KO:K12510]
BcanWSM471_05960  type II secretion system F family protein [KO:K12511]
BcanWSM471_36250  [protein-PII] uridylyltransferase [KO:K00990] [EC:2.7.7.59]
BcanWSM471_22120  P-II family nitrogen regulator [KO:K04751]
BcanWSM471_20185  nitrogen regulation protein NR(II) [KO:K07708] [EC:2.7.13.3]
BcanWSM471_20190  ntrC; nitrogen regulation protein NR(I) [KO:K07712]
BcanWSM471_22125  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
BcanWSM471_35465  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
BcanWSM471_18160  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
BcanWSM471_20200  PAS domain-containing sensor histidine kinase [KO:K13598] [EC:2.7.13.3]
BcanWSM471_20205  sigma-54 dependent transcriptional regulator [KO:K13599]
BcanWSM471_07395  nifA; nif-specific transcriptional activator NifA [KO:K02584]
BcanWSM471_19420  CoA transferase subunit A [KO:K01034] [EC:2.8.3.8 2.8.3.9]
BcanWSM471_28085  CoA transferase subunit A [KO:K01034] [EC:2.8.3.8 2.8.3.9]
BcanWSM471_19415  3-oxoacid CoA-transferase subunit B [KO:K01035] [EC:2.8.3.8 2.8.3.9]
BcanWSM471_28090  3-oxoacid CoA-transferase subunit B [KO:K01035] [EC:2.8.3.8 2.8.3.9]
BcanWSM471_22845  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_23615  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
BcanWSM471_27385  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_32425  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_33900  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_02770  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_04975  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_05835  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_08270  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_11185  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_13975  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_16980  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_17120  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
BcanWSM471_27220  dicarboxylate/amino acid:cation symporter [KO:K11103]
BcanWSM471_31375  dicarboxylate/amino acid:cation symporter [KO:K11103]
BcanWSM471_06980  dctA; C4-dicarboxylate transporter DctA [KO:K11103]
BcanWSM471_18850  dctA; C4-dicarboxylate transporter DctA [KO:K11103]
BcanWSM471_30925  dctA; C4-dicarboxylate transporter DctA [KO:K11103]
BcanWSM471_00760  rpoN; RNA polymerase factor sigma-54 [KO:K03092]
BcanWSM471_02315  protein-glutamate O-methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
BcanWSM471_09130  protein-glutamate O-methyltransferase CheR [KO:K00575] [EC:2.1.1.80]
BcanWSM471_23175  PAS domain-containing protein [KO:K13924] [EC:2.1.1.80 3.1.1.61]
BcanWSM471_23500  Cache 3/Cache 2 fusion domain-containing protein [KO:K03406]
BcanWSM471_00160  PAS domain-containing methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_30815  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_31260  PAS domain-containing methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_31305  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_32055  cache domain-containing protein [KO:K03406]
BcanWSM471_01850  PAS domain-containing methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_04680  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_06510  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_06515  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_11835  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_11840  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_13955  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_14245  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_18925  methyl-accepting chemotaxis protein [KO:K03406]
BcanWSM471_13960  methyl-accepting chemotaxis protein [KO:K03776]
BcanWSM471_02305  chemotaxis protein CheW [KO:K03408]
BcanWSM471_09115  chemotaxis protein CheW [KO:K03408]
BcanWSM471_02300  hybrid sensor histidine kinase/response regulator [KO:K03407] [EC:2.7.13.3]
BcanWSM471_09110  hybrid sensor histidine kinase/response regulator [KO:K03407] [EC:2.7.13.3]
BcanWSM471_32890  response regulator [KO:K03413]
BcanWSM471_02325  response regulator [KO:K03413]
BcanWSM471_09120  response regulator [KO:K03413]
BcanWSM471_02310  response regulator [KO:K03413]
BcanWSM471_23185  chemotaxis protein CheB [KO:K03412] [EC:3.1.1.61 3.5.1.44]
BcanWSM471_09125  chemotaxis response regulator protein-glutamate methylesterase [KO:K03412] [EC:3.1.1.61 3.5.1.44]
BcanWSM471_14995  ATP-binding protein [KO:K07716] [EC:2.7.13.3]
BcanWSM471_16165  HAMP domain-containing histidine kinase [KO:K07716] [EC:2.7.13.3]
BcanWSM471_22880  PleD family two-component system response regulator [KO:K02488] [EC:2.7.7.65]
BcanWSM471_14640  PAS domain-containing sensor histidine kinase [KO:K11357] [EC:2.7.13.3]
BcanWSM471_22885  response regulator [KO:K11443]
BcanWSM471_25775  PAS domain-containing protein [KO:K13587] [EC:2.7.13.3]
BcanWSM471_09105  histidine phosphotransferase [KO:K13588]
BcanWSM471_09165  response regulator transcription factor [KO:K13584]
BcanWSM471_33550  response regulator [KO:K13589]
BcanWSM471_34105  response regulator [KO:K13589]
BcanWSM471_28215  TRAP transporter substrate-binding protein [KO:K11688]
BcanWSM471_13095  DctP family TRAP transporter solute-binding subunit [KO:K11688]
BcanWSM471_13105  TRAP transporter large permease subunit [KO:K11690]
BcanWSM471_05720  TRAP transporter permease [KO:K11690]
BcanWSM471_13510  TRAP transporter large permease [KO:K11690]
BcanWSM471_31335  TRAP transporter large permease subunit [KO:K11690]
BcanWSM471_13160  PAS domain S-box protein [KO:K14986] [EC:2.7.13.3]
BcanWSM471_13155  response regulator transcription factor FixJ [KO:K14987]
BcanWSM471_19430  helix-turn-helix domain-containing protein [KO:K15861]
BcanWSM471_22825  helix-turn-helix domain-containing protein [KO:K15861]
BcanWSM471_13145  helix-turn-helix domain-containing protein [KO:K15861]
BcanWSM471_30610  sigma-54 dependent transcriptional regulator [KO:K10943]
BcanWSM471_33365  amino acid ABC transporter ATP-binding protein [KO:K10004] [EC:7.4.2.1]
BcanWSM471_17065  amino acid ABC transporter ATP-binding protein [KO:K10004] [EC:7.4.2.1]
BcanWSM471_33370  ABC transporter permease subunit [KO:K10002]
BcanWSM471_17070  amino acid ABC transporter permease [KO:K10002]
BcanWSM471_33375  amino acid ABC transporter permease [KO:K10003]
BcanWSM471_17075  amino acid ABC transporter permease [KO:K10003]
BcanWSM471_33380  amino acid ABC transporter substrate-binding protein [KO:K10001]
BcanWSM471_16710  amino acid ABC transporter substrate-binding protein [KO:K10001]
BcanWSM471_17080  amino acid ABC transporter substrate-binding protein [KO:K10001]
BcanWSM471_26795  Crp/Fnr family transcriptional regulator [KO:K10914]
BcanWSM471_02465  Crp/Fnr family transcriptional regulator [KO:K10914]
BcanWSM471_15255  Crp/Fnr family transcriptional regulator [KO:K10914]
BcanWSM471_26435  Crp/Fnr family transcriptional regulator [KO:K10914]
BcanWSM471_31905  Crp/Fnr family transcriptional regulator [KO:K10914]
BcanWSM471_34795  cyclic nucleotide-binding domain-containing protein [KO:K10914]
BcanWSM471_36440  cyclic nucleotide-binding domain-containing protein [KO:K10914]
BcanWSM471_21445  glsA; glutaminase A [KO:K01425] [EC:3.5.1.2]
BcanWSM471_17015  glsA; glutaminase A [KO:K01425] [EC:3.5.1.2]
BcanWSM471_36305  ActS/PrrB/RegB family redox-sensitive histidine kinase [KO:K15011] [EC:2.7.13.3]
BcanWSM471_03125  HAMP domain-containing histidine kinase [KO:K15011] [EC:2.7.13.3]
BcanWSM471_36310  ActR/PrrA/RegA family redox response regulator transcription factor [KO:K15012]
BcanWSM471_03120  response regulator transcription factor [KO:K15012]
BcanWSM471_11510  petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [KO:K00411] [EC:7.1.1.8]
BcanWSM471_11515  cytochrome b N-terminal domain-containing protein [KO:K00410]
BcanWSM471_29255  c-type cytochrome [KO:K08738]
BcanWSM471_33150  cytochrome c family protein [KO:K08738]
BcanWSM471_05905  cytochrome c family protein [KO:K08738]
BcanWSM471_13175  ccoN; cytochrome-c oxidase, cbb3-type subunit I [KO:K00404] [EC:7.1.1.9]
BcanWSM471_13180  ccoO; cytochrome-c oxidase, cbb3-type subunit II [KO:K00405]
BcanWSM471_13185  CcoQ/FixQ family Cbb3-type cytochrome c oxidase assembly chaperone [KO:K00407]
BcanWSM471_28015  cytochrome c [KO:K00406]
BcanWSM471_13190  ccoP; cytochrome-c oxidase, cbb3-type subunit III [KO:K00406]
BcanWSM471_35695  cytochrome ubiquinol oxidase subunit I [KO:K00425] [EC:7.1.1.7]
BcanWSM471_35700  cydB; cytochrome d ubiquinol oxidase subunit II [KO:K00426] [EC:7.1.1.7]
BcanWSM471_20110  TolC family outer membrane protein [KO:K12340]
BcanWSM471_14445  TolC family outer membrane protein [KO:K12340]
BcanWSM471_36525  polysaccharide export protein [KO:K01991]
BcanWSM471_09915  polysaccharide export protein [KO:K01991]
BcanWSM471_10795  polysaccharide export protein [KO:K01991]
BcanWSM471_22215  exopolysaccharide transport family protein [KO:K16692] [EC:2.7.10.3]
BcanWSM471_10875  wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) [KO:K01791] [EC:5.1.3.14]
BcanWSM471_10880  wecC; UDP-N-acetyl-D-mannosamine dehydrogenase [KO:K02472] [EC:1.1.1.336]
BcanWSM471_35080  glycoside hydrolase family 5 protein [KO:K01179] [EC:3.2.1.4]
BcanWSM471_00740  glycoside hydrolase family 5 protein [KO:K01179] [EC:3.2.1.4]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00034  Manganese
C00036  Oxaloacetate
C00038  Zinc cation
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00070  Copper
C00088  Nitrite
C00092  D-Glucose 6-phosphate
C00122  Fumarate
C00149  (S)-Malate
C00158  Citrate
C00164  Acetoacetate
C00237  CO
C00238  Potassium cation
C00244  Nitrate
C00282  Hydrogen
C00291  Nickel
C00305  Magnesium cation
C00399  Ubiquinone
C00533  Nitric oxide
C00547  L-Noradrenaline
C00697  Nitrogen
C00788  L-Adrenaline
C00828  Menaquinone
C01019  L-Fucose
C01104  Trimethylamine N-oxide
C01667  Bacitracin
C02084  Tetrathionate
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05818  2-Demethylmenaquinone
C06230  Fe-enterobactin
C06689  Vancomycin
C06696  Lead
C11612  Polymyxin B
C11842  N-(3-(S)-Hydroxybutyryl)homoserine lactone
C11849  3-Hydroxy-palmitic acid methyl ester
C12008  Ramoplanin A2
C13768  Colistin sulfate
C14819  Fe3+
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C16665  12-Methyltetradecanoic acid
C18206  cis-11-Methyl-2-dodecenoic acid
C21220  AIP-1
C21221  CSP
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21245  AgrD1 peptide
D07746  Colistin (INN)
D08401  Polymyxin B (INN)
Reference
  Authors
Yamamoto K, Hirao K, Oshima T, Aiba H, Utsumi R, Ishihama A.
  Title
Functional characterization in vitro of all two-component signal transduction systems from Escherichia coli.
  Journal
J Biol Chem 280:1448-56 (2005)
DOI:10.1074/jbc.M410104200
Reference
  Authors
Abdel-Fattah WR, Chen Y, Eldakak A, Hulett FM.
  Title
Bacillus subtilis phosphorylated PhoP: direct activation of the E(sigma)A- and repression of the E(sigma)E-responsive phoB-PS+V promoters during pho response.
  Journal
J Bacteriol 187:5166-78 (2005)
DOI:10.1128/JB.187.15.5166-5178.2005
Reference
  Authors
Navarre WW, Halsey TA, Walthers D, Frye J, McClelland M, Potter JL, Kenney LJ, Gunn JS, Fang FC, Libby SJ.
  Title
Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ.
  Journal
Mol Microbiol 56:492-508 (2005)
DOI:10.1111/j.1365-2958.2005.04553.x
Reference
  Authors
Cai SJ, Inouye M.
  Title
EnvZ-OmpR interaction and osmoregulation in Escherichia coli.
  Journal
J Biol Chem 277:24155-61 (2002)
DOI:10.1074/jbc.M110715200
Reference
  Authors
Batchelor E, Walthers D, Kenney LJ, Goulian M.
  Title
The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins ompF and ompC.
  Journal
J Bacteriol 187:5723-31 (2005)
DOI:10.1128/JB.187.16.5723-5731.2005
Reference
  Authors
Nagakubo S, Nishino K, Hirata T, Yamaguchi A.
  Title
The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC.
  Journal
J Bacteriol 184:4161-7 (2002)
DOI:10.1128/JB.184.15.4161-4167.2002
Reference
  Authors
Hagiwara D, Yamashino T, Mizuno T.
  Title
A Genome-wide view of the Escherichia coli BasS-BasR two-component system implicated in iron-responses.
  Journal
Biosci Biotechnol Biochem 68:1758-67 (2004)
DOI:10.1271/bbb.68.1758
Reference
  Authors
Munson GP, Lam DL, Outten FW, O'Halloran TV.
  Title
Identification of a copper-responsive two-component system on the chromosome of Escherichia coli K-12.
  Journal
J Bacteriol 182:5864-71 (2000)
DOI:10.1128/JB.182.20.5864-5871.2000
Reference
  Authors
Sperandio V, Torres AG, Kaper JB.
  Title
Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli.
  Journal
Mol Microbiol 43:809-21 (2002)
DOI:10.1046/j.1365-2958.2002.02803.x
Reference
  Authors
Epstein W.
  Title
The roles and regulation of potassium in bacteria.
  Journal
Prog Nucleic Acid Res Mol Biol 75:293-320 (2003)
DOI:10.1016/S0079-6603(03)75008-9
Reference
  Authors
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Related
pathway
bcan00190  Oxidative phosphorylation
bcan00550  Peptidoglycan biosynthesis
bcan00910  Nitrogen metabolism
bcan02030  Bacterial chemotaxis
bcan02040  Flagellar assembly
bcan03070  Bacterial secretion system
KO pathway
ko02020   
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