KEGG   PATHWAY: bcm00630
Entry
bcm00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia orbicola
Class
Metabolism; Carbohydrate metabolism
Pathway map
bcm00630  Glyoxylate and dicarboxylate metabolism
bcm00630

Module
bcm_M00012  Glyoxylate cycle [PATH:bcm00630]
bcm_M00621  Glycine cleavage system [PATH:bcm00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia orbicola [GN:bcm]
Gene
Bcenmc03_2067  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Bcenmc03_5860  isocitrate lyase and phosphorylmutase [KO:K01637] [EC:4.1.3.1]
Bcenmc03_5151  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Bcenmc03_5324  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Bcenmc03_6706  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Bcenmc03_2216  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Bcenmc03_1298  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Bcenmc03_2071  malate synthase A [KO:K01638] [EC:2.3.3.9]
Bcenmc03_4566  malate synthase G [KO:K01638] [EC:2.3.3.9]
Bcenmc03_3596  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Bcenmc03_2558  Citrate synthase [KO:K01647] [EC:2.3.3.1]
Bcenmc03_3589  citrate synthase I [KO:K01647] [EC:2.3.3.1]
Bcenmc03_3600  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
Bcenmc03_5605  aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
Bcenmc03_6708  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bcenmc03_1927  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bcenmc03_1814  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bcenmc03_6768  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bcenmc03_6898  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bcenmc03_2783  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bcenmc03_6830  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bcenmc03_2782  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
Bcenmc03_1813  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
Bcenmc03_0702  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Bcenmc03_0701  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Bcenmc03_0700  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Bcenmc03_3629  Catalase [KO:K03781] [EC:1.11.1.6]
Bcenmc03_6071  Catalase [KO:K03781] [EC:1.11.1.6]
Bcenmc03_4238  Catalase [KO:K03781] [EC:1.11.1.6]
Bcenmc03_0031  Catalase domain protein [KO:K03781] [EC:1.11.1.6]
Bcenmc03_6281  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Bcenmc03_2979  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Bcenmc03_1744  Gluconate 2-dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
Bcenmc03_1062  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
Bcenmc03_1662  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K00018] [EC:1.1.1.29]
Bcenmc03_1071  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
Bcenmc03_0507  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Bcenmc03_5407  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Bcenmc03_5521  HAD-superfamily hydrolase, subfamily IA, variant 3 [KO:K01091] [EC:3.1.3.18]
Bcenmc03_2167  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Bcenmc03_2181  Glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
Bcenmc03_3013  Glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
Bcenmc03_5385  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Bcenmc03_6419  Glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
Bcenmc03_0775  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Bcenmc03_5200  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Bcenmc03_0157  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
Bcenmc03_0159  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Bcenmc03_2153  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Bcenmc03_1486  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Bcenmc03_1219  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Bcenmc03_0158  glycine cleavage system H protein [KO:K02437]
Bcenmc03_1901  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
Bcenmc03_1902  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Bcenmc03_1903  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Bcenmc03_1948  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
Bcenmc03_3812  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Bcenmc03_4532  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Bcenmc03_0628  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Bcenmc03_5717  bicupin, oxalate decarboxylase family [KO:K01569] [EC:4.1.1.2]
Bcenmc03_6021  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K00122] [EC:1.17.1.9]
Bcenmc03_0989  conserved hypothetical protein [KO:K00126] [EC:1.17.1.9]
Bcenmc03_3544  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Bcenmc03_3545  molybdopterin oxidoreductase Fe4S4 region [KO:K00123] [EC:1.17.1.9]
Bcenmc03_0990  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Bcenmc03_3543  formate dehydrogenase, beta subunit [KO:K00124]
Bcenmc03_0991  NADH dehydrogenase (quinone) [KO:K00124]
Bcenmc03_0992  NADH-ubiquinone oxidoreductase 24 kD subunit-like protein [KO:K00127]
Bcenmc03_3542  formate dehydrogenase, gamma subunit [KO:K00127]
Bcenmc03_1666  esterase/lipase-like protein [KO:K01432] [EC:3.5.1.9]
Bcenmc03_2601  arylformamidase [KO:K07130] [EC:3.5.1.9]
Bcenmc03_5211  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Bcenmc03_2792  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Bcenmc03_5673  Formamidase [KO:K01455] [EC:3.5.1.49]
Bcenmc03_2183  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bcm00010  Glycolysis / Gluconeogenesis
bcm00020  Citrate cycle (TCA cycle)
bcm00030  Pentose phosphate pathway
bcm00053  Ascorbate and aldarate metabolism
bcm00071  Fatty acid degradation
bcm00230  Purine metabolism
bcm00250  Alanine, aspartate and glutamate metabolism
bcm00260  Glycine, serine and threonine metabolism
bcm00620  Pyruvate metabolism
bcm00710  Carbon fixation by Calvin cycle
bcm00750  Vitamin B6 metabolism
bcm00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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