KEGG   PATHWAY: bgk00061
Entry
bgk00061                    Pathway                                
Name
Fatty acid biosynthesis - Bradyrhizobium genosp. L
Class
Metabolism; Lipid metabolism
Pathway map
bgk00061  Fatty acid biosynthesis
bgk00061

Module
bgk_M00082  Fatty acid biosynthesis, initiation [PATH:bgk00061]
bgk_M00083  Fatty acid biosynthesis, elongation [PATH:bgk00061]
bgk_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:bgk00061]
Other DBs
GO: 0006633
Organism
Bradyrhizobium genosp. L [GN:bgk]
Gene
IC762_03225  acetyl-CoA carboxylase carboxyltransferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
IC762_16765  accB; acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
IC762_16760  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
IC762_00375  acetyl-CoA carboxylase carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
IC762_15920  fabD; ACP S-malonyltransferase [KO:K00645] [EC:2.3.1.39]
IC762_20420  ketoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
IC762_00255  fabB; beta-ketoacyl-ACP synthase I [KO:K00647] [EC:2.3.1.41]
IC762_14800  beta-ketoacyl-ACP synthase [KO:K09458] [EC:2.3.1.179]
IC762_14805  beta-ketoacyl-ACP synthase [KO:K09458] [EC:2.3.1.179]
IC762_15935  fabF; beta-ketoacyl-ACP synthase II [KO:K09458] [EC:2.3.1.179]
IC762_09955  3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
IC762_14155  SDR family NAD(P)-dependent oxidoreductase [KO:K00059] [EC:1.1.1.100]
IC762_14635  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IC762_15925  fabG; 3-oxoacyl-[acyl-carrier-protein] reductase [KO:K00059] [EC:1.1.1.100]
IC762_30570  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IC762_31385  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IC762_31865  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IC762_31870  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IC762_05080  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IC762_10080  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IC762_22690  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
IC762_22890  fabA; bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase [KO:K01716] [EC:4.2.1.59 5.3.3.14]
IC762_00260  fabA; bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase [KO:K01716] [EC:4.2.1.59 5.3.3.14]
IC762_14810  beta-hydroxyacyl-ACP dehydratase [KO:K02372] [EC:4.2.1.59]
IC762_19760  fabZ; 3-hydroxyacyl-ACP dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
IC762_00250  trans-2-enoyl-CoA reductase family protein [KO:K00209] [EC:1.3.1.9 1.3.1.44]
IC762_11470  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
IC762_14610  long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
IC762_15130  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
IC762_24750  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
IC762_33295  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
IC762_33875  pimA; dicarboxylate--CoA ligase PimA [KO:K01897] [EC:6.2.1.3]
IC762_34700  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
IC762_04380  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
IC762_04880  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
IC762_07425  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
PMID:12061798
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
PMID:12518017
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
PMID:11337402
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
PMID:17573542
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
PMID:30201289
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
PMID:25203508
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
PMID:19686777
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
PMID:27553474
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
bgk00020  Citrate cycle (TCA cycle)
bgk00071  Fatty acid degradation
bgk00074  Mycolic acid biosynthesis
bgk00410  beta-Alanine metabolism
bgk00561  Glycerolipid metabolism
bgk00564  Glycerophospholipid metabolism
bgk00620  Pyruvate metabolism
bgk00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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