KEGG   PATHWAY: bmn00630
Entry
bmn00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia mallei NCTC 10247
Class
Metabolism; Carbohydrate metabolism
Pathway map
bmn00630  Glyoxylate and dicarboxylate metabolism
bmn00630

Module
bmn_M00621  Glycine cleavage system [PATH:bmn00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia mallei NCTC 10247 [GN:bmn]
Gene
BMA10247_1361  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BMA10247_0599  acsA-2; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
BMA10247_A2054  acsA-1; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BMA10247_A0497  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BMA10247_A0504  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BMA10247_2135  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
BMA10247_A0493  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BMA10247_1076  bktB; acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
BMA10247_2729  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BMA10247_2277  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BMA10247_1081  phbA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BMA10247_1199  acetyl-CoA acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BMA10247_1080  phbB-2; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BMA10247_A0193  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BMA10247_2601  glcD; glycolate oxidase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
BMA10247_2600  glcE; glycolate oxidase, GlcE subunit [KO:K11472] [EC:1.1.99.14]
BMA10247_2599  glcF; glycolate oxidase, iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
BMA10247_1821  gyaR; glyoxylate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BMA10247_A1909  gph-2; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
BMA10247_1669  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
BMA10247_1524  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BMA10247_A1979  glyA_2; glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BMA10247_1942  glyA_1; glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BMA10247_3058  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BMA10247_3061  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
BMA10247_A2299  lpdA_3; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BMA10247_1500  lpdA_2; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BMA10247_1002  lpdA_1; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BMA10247_3060  gcvH; glycine cleavage system H protein [KO:K02437]
BMA10247_1235  glxK; glycerate kinase 1 [KO:K00865] [EC:2.7.1.165]
BMA10247_A0014  ttuC; tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BMA10247_2631  eda; 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BMA10247_A1067  oxdD; oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
BMA10247_0180  putative sulfite reductase [NADPH] flavoprotein, alpha-component [KO:K00123] [EC:1.17.1.9]
BMA10247_0181  fdsB; formate dehydrogenase, NAD-dependent, beta subunit [KO:K00124]
BMA10247_A0572  fdoH; formate dehydrogenase-O, beta subunit [KO:K00124]
BMA10247_0182  fdsG; formate dehydrogenase, NAD-dependent, gamma subunit [KO:K00127]
BMA10247_A0573  fdoI; formate dehydrogenase-O, gamma subunit [KO:K00127]
BMA10247_0652  conserved hypothetical protein [KO:K01432] [EC:3.5.1.9]
BMA10247_0100  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
BMA10247_2952  purU-1; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BMA10247_A1968  purU-2; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BMA10247_1674  hutG; N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bmn00010  Glycolysis / Gluconeogenesis
bmn00020  Citrate cycle (TCA cycle)
bmn00030  Pentose phosphate pathway
bmn00053  Ascorbate and aldarate metabolism
bmn00071  Fatty acid degradation
bmn00230  Purine metabolism
bmn00250  Alanine, aspartate and glutamate metabolism
bmn00260  Glycine, serine and threonine metabolism
bmn00620  Pyruvate metabolism
bmn00710  Carbon fixation by Calvin cycle
bmn00750  Vitamin B6 metabolism
bmn00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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