KEGG   PATHWAY: boh02024
Entry
boh02024                    Pathway                                
Name
Quorum sensing - Bordetella sp. H567
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
boh02024  Quorum sensing
boh02024

Other DBs
GO: 0009372
Organism
Bordetella sp. H567 [GN:boh]
Gene
AKI39_08590  RNA-binding protein [KO:K03666]
AKI39_22900  anthranilate synthase [KO:K01657] [EC:4.1.3.27]
AKI39_22905  anthranilate synthase [KO:K01658] [EC:4.1.3.27]
AKI39_17250  phospho-2-dehydro-3-deoxyheptonate aldolase [KO:K01626] [EC:2.5.1.54]
AKI39_16010  phospho-2-dehydro-3-deoxyheptonate aldolase [KO:K01626] [EC:2.5.1.54]
AKI39_10435  transcriptional regulator [KO:K02403]
AKI39_10440  transcriptional regulator [KO:K02402]
AKI39_18900  transcriptional regulator [KO:K07667]
AKI39_12365  ABC transporter substrate-binding protein [KO:K02055]
AKI39_01280  ABC transporter substrate-binding protein [KO:K02055]
AKI39_02025  spermidine/putrescine ABC transporter substrate-binding protein [KO:K02055]
AKI39_23895  spermidine/putrescine ABC transporter substrate-binding protein [KO:K02055]
AKI39_13850  ABC transporter substrate-binding protein [KO:K02055]
AKI39_12940  ABC transporter substrate-binding protein [KO:K02055]
AKI39_13165  ABC transporter substrate-binding protein [KO:K02055]
AKI39_17680  hypothetical protein [KO:K02055]
AKI39_12370  ABC transporter permease [KO:K02053]
AKI39_12375  ABC transporter permease [KO:K02053]
AKI39_02015  polyamine ABC transporter permease [KO:K02053]
AKI39_01250  ABC transporter permease [KO:K02053]
AKI39_23915  ABC transporter permease [KO:K02053]
AKI39_12955  ABC transporter permease [KO:K02053]
AKI39_17660  hypothetical protein [KO:K02053]
AKI39_13175  ABC transporter permease [KO:K02053 K02054]
AKI39_12950  ABC transporter permease [KO:K02054]
AKI39_01260  ABC transporter permease [KO:K02054]
AKI39_02020  polyamine ABC transporter substrate-binding protein [KO:K02054]
AKI39_23920  ABC transporter permease [KO:K02054]
AKI39_17665  hypothetical protein [KO:K02054]
AKI39_12380  ABC transporter ATP-binding protein [KO:K02052]
AKI39_01255  spermidine/putrescine ABC transporter ATPase [KO:K02052]
AKI39_02030  spermidine/putrescine ABC transporter ATPase [KO:K02052]
AKI39_23925  spermidine/putrescine ABC transporter ATPase [KO:K02052]
AKI39_12945  hypothetical protein [KO:K02052]
AKI39_13170  ABC transporter [KO:K02052]
AKI39_00165  hypothetical protein [KO:K01999]
AKI39_07555  ABC transporter permease [KO:K01999]
AKI39_12290  ABC transporter substrate-binding protein [KO:K01999]
AKI39_20450  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
AKI39_06700  amino acid-binding protein [KO:K01999]
AKI39_11135  ABC transporter substrate-binding protein [KO:K01999]
AKI39_15570  amino acid ABC transporter substrate-binding protein [KO:K01999]
AKI39_09685  ABC transporter substrate-binding protein [KO:K01999]
AKI39_14275  ABC transporter substrate-binding protein [KO:K01999]
AKI39_23170  ABC transporter permease [KO:K01999]
AKI39_23220  amino acid ABC transporter substrate-binding protein [KO:K01999]
AKI39_14865  amino acid-binding protein [KO:K01999]
AKI39_02940  ABC transporter substrate-binding protein [KO:K01999]
AKI39_00970  hypothetical protein [KO:K01999]
AKI39_23785  hypothetical protein [KO:K01999]
AKI39_06320  amino acid ABC transporter substrate-binding protein [KO:K01999]
AKI39_10900  leucine ABC transporter substrate-binding protein [KO:K01999]
AKI39_24020  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
AKI39_21840  ABC transporter substrate-binding protein [KO:K01999]
AKI39_17800  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
AKI39_04730  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
AKI39_13760  leucine ABC transporter substrate-binding protein [KO:K01999]
AKI39_07135  amino acid ABC transporter substrate-binding protein [KO:K01999]
AKI39_00170  hypothetical protein [KO:K01997]
AKI39_07550  ABC transporter permease [KO:K01997]
AKI39_20445  ABC transporter permease [KO:K01997]
AKI39_06695  ABC transporter permease [KO:K01997]
AKI39_11145  ABC transporter ATP-binding protein [KO:K01997]
AKI39_15565  ABC transporter permease [KO:K01997]
AKI39_09680  ABC transporter permease [KO:K01997 K01998]
AKI39_14270  amino acid ABC transporter permease [KO:K01997]
AKI39_23180  ABC transporter permease [KO:K01997]
AKI39_23215  ABC transporter permease [KO:K01997]
AKI39_14870  branched-chain amino acid ABC transporter permease [KO:K01997]
AKI39_02945  ABC transporter permease [KO:K01997]
AKI39_00975  hypothetical protein [KO:K01997]
AKI39_23770  hypothetical protein [KO:K01997]
AKI39_10905  branched-chain amino acid transporter permease subunit LivH [KO:K01997]
AKI39_24000  branched-chain amino acid ABC transporter permease [KO:K01997]
AKI39_21835  ABC transporter permease [KO:K01997]
AKI39_17795  ABC transporter permease [KO:K01997]
AKI39_04725  ABC transporter permease [KO:K01997]
AKI39_12295  amino acid ABC transporter permease [KO:K01997]
AKI39_06325  ABC transporter permease [KO:K01997]
AKI39_23210  ABC transporter [KO:K01995 K01998]
AKI39_14875  branched-chain amino acid ABC transporter ATP-binding protein [KO:K01995 K01998]
AKI39_00980  hypothetical protein [KO:K01995 K01998]
AKI39_04720  hypothetical protein [KO:K01995 K01998]
AKI39_02950  amino acid ABC transporter [KO:K01998]
AKI39_14265  ABC transporter permease [KO:K01998]
AKI39_23175  ABC transporter permease [KO:K01998]
AKI39_23775  hypothetical protein [KO:K01998]
AKI39_06330  ABC transporter permease [KO:K01998]
AKI39_10910  livM; leucine/isoleucine/valine transporter permease subunit [KO:K01998]
AKI39_15560  ABC transporter ATP-binding protein [KO:K01998]
AKI39_20440  ABC transporter permease [KO:K01998]
AKI39_07545  ABC transporter permease [KO:K01998]
AKI39_12300  ABC transporter permease [KO:K01998]
AKI39_00180  hypothetical protein [KO:K01995]
AKI39_09675  sugar ABC transporter ATPase [KO:K01995 K01996]
AKI39_07565  amino acid ABC transporter ATP-binding protein [KO:K01995]
AKI39_20435  ABC transporter [KO:K01995]
AKI39_06685  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01995]
AKI39_11130  ABC transporter permease [KO:K01995]
AKI39_15555  ABC transporter [KO:K01995]
AKI39_14260  ABC transporter [KO:K01995]
AKI39_23185  ABC transporter [KO:K01995]
AKI39_02955  ABC transporter [KO:K01995]
AKI39_23780  hypothetical protein [KO:K01995]
AKI39_06335  branched-chain amino acid ABC transporter ATPase [KO:K01995]
AKI39_10915  livG; leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01995]
AKI39_24010  hypothetical protein [KO:K01995]
AKI39_06340  branched-chain amino acid ABC transporter ATP-binding protein [KO:K01996]
AKI39_00185  hypothetical protein [KO:K01996]
AKI39_00985  hypothetical protein [KO:K01996]
AKI39_02960  amino acid ABC transporter ATPase [KO:K01996]
AKI39_14255  ABC transporter ATP-binding protein [KO:K01996]
AKI39_23165  branched-chain amino acid ABC transporter ATP-binding protein [KO:K01996]
AKI39_23205  ABC transporter ATP-binding protein [KO:K01996]
AKI39_14880  livF; leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01996]
AKI39_10920  livF; leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01996]
AKI39_24015  livF; leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01996]
AKI39_06680  mannosyltransferase [KO:K01996]
AKI39_15550  ABC transporter ATP-binding protein [KO:K01996]
AKI39_20430  ABC transporter [KO:K01996]
AKI39_07560  histidinol dehydrogenase [KO:K01996]
AKI39_12285  branched-chain amino acid ABC transporter ATPase [KO:K01996]
AKI39_21825  ABC transporter ATP-binding protein [KO:K01996]
AKI39_17785  metal-dependent hydrolase [KO:K01996]
AKI39_19175  pectate lyase [KO:K01728] [EC:4.2.2.2]
AKI39_10170  hypothetical protein [KO:K20276]
AKI39_23190  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
AKI39_19520  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
AKI39_11675  acetyl-CoA synthetase [KO:K01897] [EC:6.2.1.3]
AKI39_23195  Crp/Fnr family transcriptional regulator [KO:K10914]
AKI39_23435  hypothetical protein [KO:K09823]
AKI39_03025  diaminohydroxyphosphoribosylaminopyrimidine deaminase [KO:K11752] [EC:3.5.4.26 1.1.1.193]
AKI39_12080  RND transporter [KO:K18139]
AKI39_18585  multidrug transporter [KO:K18139]
AKI39_21790  peptide ABC transporter substrate-binding protein [KO:K02035]
AKI39_20550  peptide ABC transporter substrate-binding protein [KO:K02035]
AKI39_20650  transporter [KO:K02035]
AKI39_09725  hypothetical protein [KO:K02035]
AKI39_14415  ABC transporter substrate-binding protein [KO:K02035]
AKI39_18785  peptide ABC transporter [KO:K02035]
AKI39_10200  ABC transporter substrate-binding protein [KO:K02035]
AKI39_02700  peptide ABC transporter substrate-binding protein [KO:K02035]
AKI39_01525  transporter [KO:K02035]
AKI39_03055  peptide ABC transporter substrate-binding protein [KO:K02035]
AKI39_03680  peptide ABC transporter permease [KO:K02035]
AKI39_19470  hypothetical protein [KO:K02035]
AKI39_24680  peptide ABC transporter substrate-binding protein [KO:K02035]
AKI39_09175  ABC transporter substrate-binding protein [KO:K02035]
AKI39_13500  polyamine ABC transporter substrate-binding protein [KO:K02035]
AKI39_18010  ABC transporter substrate-binding protein [KO:K02035]
AKI39_07475  peptide ABC transporter substrate-binding protein [KO:K02035]
AKI39_07480  peptide ABC transporter permease [KO:K02033]
AKI39_20565  peptide ABC transporter [KO:K02033]
AKI39_09705  ABC transporter permease [KO:K02033]
AKI39_14410  peptide ABC transporter [KO:K02033]
AKI39_18790  peptide ABC transporter [KO:K02033]
AKI39_10205  peptide ABC transporter [KO:K02033]
AKI39_03685  peptide ABC transporter [KO:K02033]
AKI39_03060  ABC transporter permease [KO:K02033]
AKI39_02680  peptide ABC transporter [KO:K02033]
AKI39_19460  hypothetical protein [KO:K02033]
AKI39_24685  ABC transporter permease [KO:K02033]
AKI39_09170  ABC transporter permease [KO:K02033]
AKI39_22525  ABC transporter permease [KO:K02033]
AKI39_13530  glutathione ABC transporter permease [KO:K02033]
AKI39_20560  peptide ABC transporter permease [KO:K02034]
AKI39_09700  peptide ABC transporter permease [KO:K02034]
AKI39_14405  diguanylate cyclase [KO:K02034]
AKI39_18795  peptide ABC transporter permease [KO:K02034]
AKI39_10210  peptide ABC transporter permease [KO:K02034]
AKI39_03690  peptide ABC transporter permease [KO:K02034]
AKI39_03065  peptide ABC transporter permease [KO:K02034]
AKI39_19455  hypothetical protein [KO:K02034]
AKI39_02685  peptide ABC transporter permease [KO:K02034]
AKI39_24690  peptide ABC transporter permease [KO:K02034]
AKI39_09165  peptide ABC transporter permease [KO:K02034]
AKI39_13535  ABC transporter permease [KO:K02034]
AKI39_22530  peptide ABC transporter permease [KO:K02034]
AKI39_20555  glutathione ABC transporter ATP-binding protein [KO:K02031 K02032]
AKI39_03050  glutathione ABC transporter ATP-binding protein [KO:K02031 K02032]
AKI39_07490  ABC transporter ATP-binding protein [KO:K02031 K02032]
AKI39_14400  glutathione ABC transporter ATP-binding protein [KO:K02031 K02032]
AKI39_18800  dppD; peptide ABC transporter ATP-binding protein [KO:K02031]
AKI39_02690  peptide ABC transporter ATP-binding protein [KO:K02031 K02032]
AKI39_03695  peptide ABC transporter ATP-binding protein [KO:K02031]
AKI39_24695  methionine ABC transporter ATP-binding protein [KO:K02031]
AKI39_09160  peptide ABC transporter substrate-binding protein [KO:K02031]
AKI39_13540  peptide ABC transporter ATPase [KO:K02031]
AKI39_22535  methionine ABC transporter ATP-binding protein [KO:K02031]
AKI39_03700  peptide ABC transporter substrate-binding protein [KO:K02032]
AKI39_18805  peptide ABC transporter ATP-binding protein [KO:K02032]
AKI39_24735  insertase [KO:K03217]
AKI39_24550  preprotein translocase subunit SecE [KO:K03073]
AKI39_18310  preprotein translocase subunit SecG [KO:K03075]
AKI39_24325  secY; preprotein translocase subunit SecY [KO:K03076]
AKI39_04195  preprotein translocase subunit YajC [KO:K03210]
AKI39_19595  secA; preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
AKI39_02560  cell division protein FtsY [KO:K03110]
AKI39_23000  preprotein translocase subunit SecB [KO:K03071]
AKI39_01945  signal recognition particle [KO:K03106] [EC:3.6.5.4]
AKI39_10050  phospholipase [KO:K01114] [EC:3.1.4.3]
AKI39_14520  hypothetical protein [KO:K01114] [EC:3.1.4.3]
AKI39_24090  phospholipase [KO:K01114] [EC:3.1.4.3]
AKI39_09275  phospholipase [KO:K01114] [EC:3.1.4.3]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
PMID:17376080
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
PMID:21622734
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
PMID:21504831
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
PMID:16513747
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
PMID:20514483
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
PMID:26579084
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
PMID:18851841
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
PMID:25714717
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
DOI:10.1128/mBio.02569-14
Reference
PMID:25824838
  Authors
Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
  Journal
Infect Immun 83:2430-42 (2015)
DOI:10.1128/IAI.00240-15
Reference
PMID:19363118
  Authors
Ohtani K, Yuan Y, Hassan S, Wang R, Wang Y, Shimizu T
  Title
Virulence gene regulation by the agr system in Clostridium perfringens.
  Journal
J Bacteriol 191:3919-27 (2009)
DOI:10.1128/JB.01455-08
Reference
PMID:22736963
  Authors
Li YH, Tian X
  Title
Quorum sensing and bacterial social interactions in biofilms.
  Journal
Sensors (Basel) 12:2519-38 (2012)
DOI:10.3390/s120302519
Reference
PMID:22407687
  Authors
Berg KH, Biornstad TJ, Johnsborg O, Havarstein LS
  Title
Properties and biological role of streptococcal fratricins.
  Journal
Appl Environ Microbiol 78:3515-22 (2012)
DOI:10.1128/AEM.00098-12
Reference
PMID:25475081
  Authors
Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Dobler I, Zeng AP
  Title
Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.
  Journal
J Oral Microbiol 6:26189 (2014)
DOI:10.3402/jom.v6.26189
Reference
PMID:25309879
  Authors
Jimenez JC, Federle MJ
  Title
Quorum sensing in group A Streptococcus.
  Journal
Front Cell Infect Microbiol 4:127 (2014)
DOI:10.3389/fcimb.2014.00127
Reference
PMID:24118108
  Authors
Cook LC, Federle MJ
  Title
Peptide pheromone signaling in Streptococcus and Enterococcus.
  Journal
FEMS Microbiol Rev 38:473-92 (2014)
DOI:10.1111/1574-6976.12046
Reference
PMID:9680220
  Authors
Podbielski A, Leonard BA
  Title
The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease.
  Journal
Mol Microbiol 28:1323-34 (1998)
DOI:10.1046/j.1365-2958.1998.00898.x
Reference
PMID:8885277
  Authors
Podbielski A, Pohl B, Woischnik M, Korner C, Schmidt KH, Rozdzinski E, Leonard BA
  Title
Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease production.
  Journal
Mol Microbiol 21:1087-99 (1996)
DOI:10.1046/j.1365-2958.1996.661421.x
Reference
PMID:22636768
  Authors
Anbalagan S, Dmitriev A, McShan WM, Dunman PM, Chaussee MS
  Title
Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes.
  Journal
J Bacteriol 194:3961-71 (2012)
DOI:10.1128/JB.06709-11
Reference
PMID:22016844
  Authors
Clewell DB
  Title
Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey.
  Journal
Mob Genet Elements 1:38-54 (2011)
DOI:10.4161/mge.1.1.15409
Reference
PMID:20734751
  Authors
Wardal E, Sadowy E, Hryniewicz W
  Title
Complex nature of enterococcal pheromone-responsive plasmids.
  Journal
Pol J Microbiol 59:79-87 (2010)
Reference
PMID:19683678
  Authors
Roux A, Payne SM, Gilmore MS
  Title
Microbial telesensing: probing the environment for friends, foes, and food.
  Journal
Cell Host Microbe 6:115-24 (2009)
DOI:10.1016/j.chom.2009.07.004
Reference
PMID:25089349
  Authors
Slamti L, Perchat S, Huillet E, Lereclus D
  Title
Quorum sensing in Bacillus thuringiensis is required for completion of a full infectious cycle in the insect.
  Journal
Toxins (Basel) 6:2239-55 (2014)
DOI:10.3390/toxins6082239
Reference
PMID:20030732
  Authors
Lopez D, Kolter R
  Title
Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis.
  Journal
FEMS Microbiol Rev 34:134-49 (2010)
DOI:10.1111/j.1574-6976.2009.00199.x
Reference
PMID:12897006
  Authors
Stephenson S, Mueller C, Jiang M, Perego M
  Title
Molecular analysis of Phr peptide processing in Bacillus subtilis.
  Journal
J Bacteriol 185:4861-71 (2003)
DOI:10.1128/JB.185.16.4861-4871.2003
Reference
PMID:17666034
  Authors
Lanigan-Gerdes S, Dooley AN, Faull KF, Lazazzera BA
  Title
Identification of subtilisin, Epr and Vpr as enzymes that produce CSF, an extracellular signalling peptide of Bacillus subtilis.
  Journal
Mol Microbiol 65:1321-33 (2007)
DOI:10.1111/j.1365-2958.2007.05869.x
Reference
PMID:15374644
  Authors
Kleerebezem M
  Title
Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis.
  Journal
Peptides 25:1405-14 (2004)
DOI:10.1016/j.peptides.2003.10.021
Reference
PMID:23125205
  Authors
Rutherford ST, Bassler BL
  Title
Bacterial quorum sensing: its role in virulence and possibilities for its control.
  Journal
Cold Spring Harb Perspect Med 2:a012427 (2012)
DOI:10.1101/cshperspect.a012427
Reference
PMID:23471618
  Authors
LaSarre B, Federle MJ
  Title
Exploiting quorum sensing to confuse bacterial pathogens.
  Journal
Microbiol Mol Biol Rev 77:73-111 (2013)
DOI:10.1128/MMBR.00046-12
Reference
PMID:18781869
  Authors
Sifri CD
  Title
Healthcare epidemiology: quorum sensing: bacteria talk sense.
  Journal
Clin Infect Dis 47:1070-6 (2008)
DOI:10.1086/592072
Related
pathway
boh00405  Phenazine biosynthesis
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KO pathway
ko02024   
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