KEGG   PATHWAY: bros00630
Entry
bros00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Bradyrhizobium roseum
Class
Metabolism; Carbohydrate metabolism
Pathway map
bros00630  Glyoxylate and dicarboxylate metabolism
bros00630

Module
bros_M00012  Glyoxylate cycle [PATH:bros00630]
bros_M00621  Glycine cleavage system [PATH:bros00630]
bros_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:bros00630]
Other DBs
GO: 0046487 0043648
Organism
Bradyrhizobium roseum [GN:bros]
Gene
QUH67_08525  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
QUH67_01285  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
QUH67_06080  acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
QUH67_20695  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
QUH67_04985  malate synthase G [KO:K01638] [EC:2.3.3.9]
QUH67_01935  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
QUH67_03225  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
QUH67_03230  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
QUH67_16740  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
QUH67_01885  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
QUH67_26105  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
QUH67_27330  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
QUH67_28720  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
QUH67_31945  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
QUH67_03015  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
QUH67_03420  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
QUH67_09325  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
QUH67_11215  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
QUH67_14360  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
QUH67_20825  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
QUH67_03020  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
QUH67_30385  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
QUH67_16460  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
QUH67_14575  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
QUH67_14250  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
QUH67_12220  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
QUH67_12230  methylmalonyl-CoA mutase family protein [KO:K01847] [EC:5.4.99.2]
QUH67_30315  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
QUH67_30305  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
QUH67_30300  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
QUH67_25475  catalase [KO:K03781] [EC:1.11.1.6]
QUH67_31090  catalase [KO:K03781] [EC:1.11.1.6]
QUH67_00320  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
QUH67_22450  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
QUH67_05395  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
QUH67_12780  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
QUH67_22070  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
QUH67_08995  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
QUH67_10280  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
QUH67_20395  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
QUH67_10025  form I ribulose bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
QUH67_10030  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
QUH67_02340  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
QUH67_11590  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
QUH67_33695  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
QUH67_15940  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
QUH67_19670  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
QUH67_15610  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
QUH67_24725  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
QUH67_24715  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
QUH67_01975  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
QUH67_16995  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
QUH67_24720  gcvH; glycine cleavage system protein GcvH [KO:K02437]
QUH67_12720  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
QUH67_12725  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
QUH67_12730  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
QUH67_04275  glycerate kinase [KO:K11529] [EC:2.7.1.165]
QUH67_26225  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
QUH67_17060  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
QUH67_20830  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
QUH67_07895  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
QUH67_12865  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
QUH67_07890  NAD(P)H-dependent oxidoreductase subunit E [KO:K22515] [EC:1.17.1.9]
QUH67_12870  fdh3B; formate dehydrogenase FDH3 subunit beta [KO:K00124]
QUH67_12875  formate dehydrogenase subunit gamma [KO:K00127]
QUH67_27260  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
QUH67_26240  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
QUH67_25720  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
QUH67_27345  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
QUH67_12670  oxc; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
QUH67_12665  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bros00010  Glycolysis / Gluconeogenesis
bros00020  Citrate cycle (TCA cycle)
bros00030  Pentose phosphate pathway
bros00053  Ascorbate and aldarate metabolism
bros00071  Fatty acid degradation
bros00230  Purine metabolism
bros00250  Alanine, aspartate and glutamate metabolism
bros00260  Glycine, serine and threonine metabolism
bros00620  Pyruvate metabolism
bros00710  Carbon fixation by Calvin cycle
bros00750  Vitamin B6 metabolism
bros00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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