KEGG   PATHWAY: btha00630
Entry
btha00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia thailandensis 2003015869
Class
Metabolism; Carbohydrate metabolism
Pathway map
btha00630  Glyoxylate and dicarboxylate metabolism
btha00630

Module
btha_M00012  Glyoxylate cycle [PATH:btha00630]
btha_M00621  Glycine cleavage system [PATH:btha00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia thailandensis 2003015869 [GN:btha]
Gene
DR62_3231  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
DR62_4531  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DR62_4253  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DR62_2491  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DR62_3463  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
DR62_4581  malate synthase [KO:K01638] [EC:2.3.3.9]
DR62_3235  malate synthase [KO:K01638] [EC:2.3.3.9]
DR62_5614  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DR62_4064  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DR62_5621  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
DR62_1950  citrate synthase [KO:K01647] [EC:2.3.3.1]
DR62_3600  citrate synthase [KO:K01647] [EC:2.3.3.1]
DR62_5610  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
DR62_2975  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DR62_2980  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DR62_3089  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DR62_1250  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DR62_1538  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DR62_5372  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DR62_2979  3-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
DR62_576  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
DR62_577  glcE; glycolate oxidase [KO:K11472] [EC:1.1.99.14]
DR62_578  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
DR62_1259  catalase [KO:K03781] [EC:1.11.1.6]
DR62_1508  glyoxylate reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DR62_2938  bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DR62_152  2-hydroxyacid dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DR62_777  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
DR62_143  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DR62_3870  hydrolase [KO:K01091] [EC:3.1.3.18]
DR62_25  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DR62_3366  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DR62_4402  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DR62_4326  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DR62_483  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DR62_1118  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
DR62_1116  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
DR62_4818  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR62_2686  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR62_3343  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR62_1117  glycine cleavage system H protein [KO:K02437]
DR62_3063  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
DR62_3064  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
DR62_3065  tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
DR62_5117  glycerate kinase [KO:K00865] [EC:2.7.1.165]
DR62_3115  glycerate kinase [KO:K00865] [EC:2.7.1.165]
DR62_4899  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DR62_647  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DR62_3568  cupin [KO:K01569] [EC:4.1.1.2]
DR62_229  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
DR62_228  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
DR62_5661  sulfate ABC transporter substrate-binding protein [KO:K00123] [EC:1.17.1.9]
DR62_5662  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
DR62_227  formate dehydrogenase [KO:K00124]
DR62_5663  formate dehydrogenase [KO:K00124]
DR62_226  formate dehydrogenase [KO:K00127]
DR62_5664  formate dehydrogenase [KO:K00127]
DR62_1909  kynurenine formamidase [KO:K07130] [EC:3.5.1.9]
DR62_4315  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DR62_1690  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DR62_27  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
btha00010  Glycolysis / Gluconeogenesis
btha00020  Citrate cycle (TCA cycle)
btha00030  Pentose phosphate pathway
btha00053  Ascorbate and aldarate metabolism
btha00071  Fatty acid degradation
btha00230  Purine metabolism
btha00250  Alanine, aspartate and glutamate metabolism
btha00260  Glycine, serine and threonine metabolism
btha00620  Pyruvate metabolism
btha00710  Carbon fixation by Calvin cycle
btha00750  Vitamin B6 metabolism
btha00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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