KEGG   PATHWAY: bul00630
Entry
bul00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia sp. 2002721687
Class
Metabolism; Carbohydrate metabolism
Pathway map
bul00630  Glyoxylate and dicarboxylate metabolism
bul00630

Module
bul_M00012  Glyoxylate cycle [PATH:bul00630]
bul_M00621  Glycine cleavage system [PATH:bul00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia sp. 2002721687 [GN:bul]
Gene
BW21_1580  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BW21_2470  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BW21_5112  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BW21_3880  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BW21_1576  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
BW21_3773  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BW21_3766  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BW21_3072  merR regulatory family protein [KO:K01647] [EC:2.3.3.1]
BW21_3777  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BW21_2661  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BW21_1724  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW21_137  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW21_1842  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW21_1848  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW21_3511  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BW21_4610  phbB; acetoacetyl-CoA reductase family protein [KO:K00023] [EC:1.1.1.36]
BW21_1843  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BW21_860  FAD binding domain protein [KO:K00104] [EC:1.1.99.14]
BW21_859  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
BW21_858  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
BW21_4220  catalase family protein [KO:K03781] [EC:1.11.1.6]
BW21_128  catalase family protein [KO:K03781] [EC:1.11.1.6]
BW21_3545  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BW21_1318  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BW21_1901  ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BW21_617  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
BW21_1327  HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
BW21_3853  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BW21_1446  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BW21_1463  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BW21_5058  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
BW21_942  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
BW21_274  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BW21_276  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
BW21_2271  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BW21_1484  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BW21_4371  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BW21_275  gcvH; glycine cleavage system H protein [KO:K02437]
BW21_1750  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BW21_1749  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BW21_1748  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BW21_4187  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BW21_1698  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BW21_4274  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BW21_774  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BW21_5472  bicupin, oxalate decarboxylase family protein [KO:K01569] [EC:4.1.1.2]
BW21_1173  NADH-dependent formate dehydrogenase delta subunit FdsD family protein [KO:K00126] [EC:1.17.1.9]
BW21_1174  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BW21_3701  fdnG; formate dehydrogenase-N alpha subunit [KO:K00123] [EC:1.17.1.9]
BW21_3702  Tat (twin-arginine translocation) pathway signal sequence domain protein [KO:K00123] [EC:1.17.1.9]
BW21_1175  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
BW21_3700  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
BW21_1176  thioredoxin-like [2Fe-2S] ferredoxin family protein [KO:K00127]
BW21_3699  formate dehydrogenase, gamma subunit [KO:K00127]
BW21_3114  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
BW21_3353  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BW21_5069  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BW21_1444  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bul00010  Glycolysis / Gluconeogenesis
bul00020  Citrate cycle (TCA cycle)
bul00030  Pentose phosphate pathway
bul00053  Ascorbate and aldarate metabolism
bul00071  Fatty acid degradation
bul00230  Purine metabolism
bul00250  Alanine, aspartate and glutamate metabolism
bul00260  Glycine, serine and threonine metabolism
bul00620  Pyruvate metabolism
bul00710  Carbon fixation by Calvin cycle
bul00750  Vitamin B6 metabolism
bul00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system