KEGG   PATHWAY: cng00630
Entry
cng00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cryptococcus neoformans var. grubii H99
Class
Metabolism; Carbohydrate metabolism
Pathway map
cng00630  Glyoxylate and dicarboxylate metabolism
cng00630

Module
cng_M00012  Glyoxylate cycle [PATH:cng00630]
cng_M00621  Glycine cleavage system [PATH:cng00630]
Other DBs
GO: 0046487 0043648
Organism
Cryptococcus neoformans var. grubii H99 [GN:cng]
Gene
CNAG_05303  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
CNAG_00797  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
CNAG_05653  malate synthase A [KO:K01638] [EC:2.3.3.9]
CNAG_03266  malate dehydrogenase, NAD-dependent [KO:K00026] [EC:1.1.1.37]
CNAG_03225  malate dehydrogenase, NAD-dependent [KO:K00026] [EC:1.1.1.37]
CNAG_00061  citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
CNAG_01137  aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
CNAG_03427  aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
CNAG_02918  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CNAG_01080  glycolate oxidase [KO:K11517] [EC:1.1.3.15]
CNAG_00575  catalase [KO:K03781] [EC:1.11.1.6]
CNAG_04981  catalase [KO:K03781] [EC:1.11.1.6]
CNAG_05015  catalase [KO:K03781] [EC:1.11.1.6]
CNAG_05256  catalase [KO:K03781] [EC:1.11.1.6]
CNAG_01794  2-hydroxyacid dehydrogenase [KO:K00015] [EC:1.1.1.26]
CNAG_00836  2-hydroxyacid dehydrogenase [KO:K00015] [EC:1.1.1.26]
CNAG_01777  glyoxylate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
CNAG_07808  alanine-glyoxylate transaminase/serine-glyoxylate transaminase/serine-pyruvate transaminase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
CNAG_00457  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CNAG_00710  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CNAG_04601  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CNAG_01594  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
CNAG_02818  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
CNAG_07004  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CNAG_06316  glycine cleavage system H protein [KO:K02437]
CNAG_07779  D-glycerate 3-kinase [KO:K15918] [EC:2.7.1.31]
CNAG_02781  dihydrodipicolinate synthetase [KO:K18123] [EC:4.1.3.16]
CNAG_06672  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cng00010  Glycolysis / Gluconeogenesis
cng00020  Citrate cycle (TCA cycle)
cng00030  Pentose phosphate pathway
cng00053  Ascorbate and aldarate metabolism
cng00071  Fatty acid degradation
cng00230  Purine metabolism
cng00250  Alanine, aspartate and glutamate metabolism
cng00260  Glycine, serine and threonine metabolism
cng00620  Pyruvate metabolism
cng00710  Carbon fixation by Calvin cycle
cng00750  Vitamin B6 metabolism
cng00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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