KEGG   PATHWAY: cobb00630
Entry
cobb00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cobetia sp. 4B
Class
Metabolism; Carbohydrate metabolism
Pathway map
cobb00630  Glyoxylate and dicarboxylate metabolism
cobb00630

Module
cobb_M00621  Glycine cleavage system [PATH:cobb00630]
Other DBs
GO: 0046487 0043648
Organism
Cobetia sp. 4B [GN:cobb]
Gene
H2O77_14020  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
H2O77_15065  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
H2O77_02760  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
H2O77_00380  malate synthase G [KO:K01638] [EC:2.3.3.9]
H2O77_02515  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
H2O77_16055  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
H2O77_12770  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
H2O77_00770  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
H2O77_02750  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
H2O77_16385  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
H2O77_06020  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
H2O77_06015  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
H2O77_06010  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
H2O77_10810  catalase [KO:K03781] [EC:1.11.1.6]
H2O77_02655  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
H2O77_02660  catalase [KO:K03781] [EC:1.11.1.6]
H2O77_07825  hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
H2O77_14440  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
H2O77_08780  D-2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
H2O77_07445  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
H2O77_03075  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
H2O77_04420  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
H2O77_17285  glnA; glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
H2O77_03305  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
H2O77_03320  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
H2O77_13315  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
H2O77_02220  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
H2O77_06125  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
H2O77_07425  DUF1989 domain-containing protein [KO:K00605] [EC:2.1.2.10]
H2O77_06140  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
H2O77_02550  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
H2O77_06045  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
H2O77_06130  gcvH; glycine cleavage system protein GcvH [KO:K02437]
H2O77_12090  glycerate kinase [KO:K00865] [EC:2.7.1.165]
H2O77_06795  aldA; aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
H2O77_07090  aldA; aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
H2O77_10760  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
H2O77_03770  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
H2O77_08540  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
H2O77_02155  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
H2O77_02150  NAD(P)H-dependent oxidoreductase subunit E [KO:K22515] [EC:1.17.1.9]
H2O77_08535  4Fe-4S dicluster domain-containing protein [KO:K00124]
H2O77_08530  formate dehydrogenase subunit gamma [KO:K00127]
H2O77_12180  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
H2O77_02245  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cobb00010  Glycolysis / Gluconeogenesis
cobb00020  Citrate cycle (TCA cycle)
cobb00030  Pentose phosphate pathway
cobb00053  Ascorbate and aldarate metabolism
cobb00071  Fatty acid degradation
cobb00230  Purine metabolism
cobb00250  Alanine, aspartate and glutamate metabolism
cobb00260  Glycine, serine and threonine metabolism
cobb00620  Pyruvate metabolism
cobb00710  Carbon fixation by Calvin cycle
cobb00750  Vitamin B6 metabolism
cobb00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system