KEGG   PATHWAY: cup00630
Entry
cup00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cupriavidus malaysiensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
cup00630  Glyoxylate and dicarboxylate metabolism
cup00630

Module
cup_M00012  Glyoxylate cycle [PATH:cup00630]
cup_M00621  Glycine cleavage system [PATH:cup00630]
Other DBs
GO: 0046487 0043648
Organism
Cupriavidus malaysiensis [GN:cup]
Gene
BKK80_33565  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BKK80_14110  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BKK80_08100  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
BKK80_15405  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BKK80_25330  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
BKK80_22745  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
BKK80_14085  malate synthase A [KO:K01638] [EC:2.3.3.9]
BKK80_15905  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BKK80_28425  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
BKK80_15870  citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BKK80_30010  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
BKK80_15930  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BKK80_31940  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
BKK80_11480  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_34010  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_23415  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_12820  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_12860  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_25525  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_10390  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_29085  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_26580  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_30200  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_02570  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK80_10615  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BKK80_12855  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BKK80_30275  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BKK80_12135  hypothetical protein [KO:K17865] [EC:4.2.1.55]
BKK80_12615  acetyl/propionyl-CoA carboxylase subuit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
BKK80_17865  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
BKK80_17875  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
BKK80_17880  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
BKK80_02630  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BKK80_21515  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BKK80_01955  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BKK80_15690  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BKK80_18810  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BKK80_15650  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
BKK80_27340  hydrolase [KO:K01091] [EC:3.1.3.18]
BKK80_16720  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BKK80_00555  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
BKK80_00545  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
BKK80_14555  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK80_31530  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK80_29170  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK80_13110  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK80_00550  glycine cleavage system protein H [KO:K02437]
BKK80_00380  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BKK80_00385  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BKK80_26010  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BKK80_00390  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BKK80_17460  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BKK80_21540  glycerate kinase [KO:K11529] [EC:2.7.1.165]
BKK80_00395  glycerate kinase [KO:K11529] [EC:2.7.1.165]
BKK80_04105  glycerate kinase [KO:K11529] [EC:2.7.1.165]
BKK80_21550  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK80_24460  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK80_04100  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK80_20965  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK80_25800  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BKK80_05110  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
BKK80_29650  sulfate ABC transporter substrate-binding protein [KO:K00123] [EC:1.17.1.9]
BKK80_29655  formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
BKK80_05105  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
BKK80_29660  formate dehydrogenase subunit beta [KO:K00124]
BKK80_05100  formate dehydrogenase [KO:K00124]
BKK80_29665  formate dehydrogenase subunit gamma [KO:K00127]
BKK80_05095  formate dehydrogenase subunit gamma [KO:K00127]
BKK80_25115  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
BKK80_16625  arylformamidase [KO:K07130] [EC:3.5.1.9]
BKK80_15280  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BKK80_34030  formamidase [KO:K01455] [EC:3.5.1.49]
BKK80_29810  formamidase [KO:K01455] [EC:3.5.1.49]
BKK80_17485  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cup00010  Glycolysis / Gluconeogenesis
cup00020  Citrate cycle (TCA cycle)
cup00030  Pentose phosphate pathway
cup00053  Ascorbate and aldarate metabolism
cup00071  Fatty acid degradation
cup00230  Purine metabolism
cup00250  Alanine, aspartate and glutamate metabolism
cup00260  Glycine, serine and threonine metabolism
cup00620  Pyruvate metabolism
cup00710  Carbon fixation by Calvin cycle
cup00750  Vitamin B6 metabolism
cup00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system