KEGG   PATHWAY: haer00630
Entry
haer00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Haloplanus aerogenes
Class
Metabolism; Carbohydrate metabolism
Pathway map
haer00630  Glyoxylate and dicarboxylate metabolism
haer00630

Module
haer_M00621  Glycine cleavage system [PATH:haer00630]
Other DBs
GO: 0046487 0043648
Organism
Haloplanus aerogenes [GN:haer]
Gene
DU502_02910  isocitrate lyase/PEP mutase family protein [KO:K01637] [EC:4.1.3.1]
DU502_08825  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
DU502_06935  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DU502_00675  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DU502_04360  citrate synthase [KO:K01647] [EC:2.3.3.1]
DU502_02615  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
DU502_02665  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
DU502_16810  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
DU502_07585  thiolase family protein [KO:K00626] [EC:2.3.1.9]
DU502_05235  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DU502_06480  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DU502_07600  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
DU502_17035  hypothetical protein [KO:K05606] [EC:5.1.99.1]
DU502_10980  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DU502_08525  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
DU502_10695  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
DU502_06460  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
DU502_11015  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
DU502_15325  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DU502_07060  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DU502_15065  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DU502_13435  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
DU502_10080  hypothetical protein [KO:K01601] [EC:4.1.1.39]
DU502_06280  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
DU502_05770  glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
DU502_00325  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DU502_17675  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DU502_14175  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DU502_00290  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DU502_00305  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
DU502_00300  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
DU502_14270  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DU502_16570  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
DU502_00275  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DU502_14265  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DU502_12920  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
DU502_05660  class II aldolase/adducin family protein [KO:K01636] [EC:4.1.2.-]
DU502_16960  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DU502_03740  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DU502_13710  twin-arginine translocation signal domain-containing protein [KO:K00123] [EC:1.17.1.9]
DU502_13715  4Fe-4S dicluster domain-containing protein [KO:K00124]
DU502_03680  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
DU502_03700  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
haer00010  Glycolysis / Gluconeogenesis
haer00020  Citrate cycle (TCA cycle)
haer00030  Pentose phosphate pathway
haer00053  Ascorbate and aldarate metabolism
haer00071  Fatty acid degradation
haer00230  Purine metabolism
haer00250  Alanine, aspartate and glutamate metabolism
haer00260  Glycine, serine and threonine metabolism
haer00620  Pyruvate metabolism
haer00710  Carbon fixation by Calvin cycle
haer00750  Vitamin B6 metabolism
haer00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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