KEGG   PATHWAY: hak00630
Entry
hak00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halomonas sp. KO116
Class
Metabolism; Carbohydrate metabolism
Pathway map
hak00630  Glyoxylate and dicarboxylate metabolism
hak00630

Module
hak_M00012  Glyoxylate cycle [PATH:hak00630]
hak_M00621  Glycine cleavage system [PATH:hak00630]
Other DBs
GO: 0046487 0043648
Organism
Halomonas sp. KO116 [GN:hak]
Gene
KO116_03113  Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
KO116_01747  Acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
KO116_01089  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
KO116_00305  Malate synthase G [KO:K01638] [EC:2.3.3.9]
KO116_00954  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
KO116_03171  citrate synthase I [KO:K01647] [EC:2.3.3.1]
KO116_00074  Citrate synthase [KO:K01647] [EC:2.3.3.1]
KO116_01429  aconitate hydratase domain-containing protein [KO:K01681] [EC:4.2.1.3]
KO116_00916  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
KO116_02038  aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
KO116_P100008  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KO116_03996  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KO116_01745  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KO116_00185  Acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
KO116_03854  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
KO116_03287  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
KO116_01114  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
KO116_01112  FAD linked oxidase domain-containing protein [KO:K11472] [EC:1.1.99.14]
KO116_01111  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
KO116_03183  Catalase [KO:K03781] [EC:1.11.1.6]
KO116_01202  Hydroxypyruvate reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KO116_01527  Glyoxylate reductase (NADP(+)) [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KO116_02268  Glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
KO116_02869  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
KO116_02633  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
KO116_01124  Serine--glyoxylate transaminase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
KO116_04124  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
KO116_00438  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KO116_00417  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KO116_03004  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KO116_00537  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KO116_02302  Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
KO116_02299  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
KO116_03164  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
KO116_02189  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
KO116_02301  Glycine cleavage system H protein [KO:K02437]
KO116_00592  Xylose isomerase domain-containing protein TIM barrel [KO:K01816] [EC:5.3.1.22]
KO116_02314  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
KO116_01007  glycerate kinase [KO:K00865] [EC:2.7.1.165]
KO116_01616  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KO116_01834  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
KO116_00526  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
KO116_00740  Nitrate reductase [KO:K00123] [EC:1.17.1.9]
KO116_P100147  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
KO116_00525  Respiratory-chain NADH dehydrogenase domain 51 kDa subunit [KO:K22515] [EC:1.17.1.9]
KO116_00741  4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein [KO:K00124]
KO116_00742  formate dehydrogenase, gamma subunit [KO:K00127]
KO116_00934  Arylformamidase [KO:K01432] [EC:3.5.1.9]
KO116_00443  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
KO116_00423  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
KO116_02026  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
KO116_00542  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hak00010  Glycolysis / Gluconeogenesis
hak00020  Citrate cycle (TCA cycle)
hak00030  Pentose phosphate pathway
hak00053  Ascorbate and aldarate metabolism
hak00071  Fatty acid degradation
hak00230  Purine metabolism
hak00250  Alanine, aspartate and glutamate metabolism
hak00260  Glycine, serine and threonine metabolism
hak00620  Pyruvate metabolism
hak00710  Carbon fixation by Calvin cycle
hak00750  Vitamin B6 metabolism
hak00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system