KEGG   PATHWAY: harr00061
Entry
harr00061                   Pathway                                
Name
Fatty acid biosynthesis - Halopseudomonas maritima
Class
Metabolism; Lipid metabolism
Pathway map
harr00061  Fatty acid biosynthesis
harr00061

Module
harr_M00082  Fatty acid biosynthesis, initiation [PATH:harr00061]
harr_M00083  Fatty acid biosynthesis, elongation [PATH:harr00061]
harr_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:harr00061]
Other DBs
GO: 0006633
Organism
Halopseudomonas maritima [GN:harr]
Gene
HV822_13590  accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
HV822_14055  accB; acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
HV822_14050  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
HV822_01735  accD; acetyl-CoA carboxylase, carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
HV822_16190  fabD; ACP S-malonyltransferase [KO:K00645] [EC:2.3.1.39]
HV822_10135  beta-ketoacyl synthase [KO:K18473] [EC:2.3.1.180]
HV822_16535  fabB; beta-ketoacyl-ACP synthase I [KO:K00647] [EC:2.3.1.41]
HV822_00075  fabF; beta-ketoacyl-ACP synthase II [KO:K09458] [EC:2.3.1.179]
HV822_16205  fabF; beta-ketoacyl-ACP synthase II [KO:K09458] [EC:2.3.1.179]
HV822_04130  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
HV822_16195  fabG; 3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
HV822_16845  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
HV822_17105  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
HV822_17680  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
HV822_17805  3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
HV822_16540  fabA; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA [KO:K01716] [EC:4.2.1.59 5.3.3.14]
HV822_13565  fabZ; 3-hydroxyacyl-ACP dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
HV822_15790  enoyl-ACP reductase [KO:K00208] [EC:1.3.1.9 1.3.1.10]
HV822_01560  fadD1; long-chain-fatty-acid--CoA ligase FadD1 [KO:K01897] [EC:6.2.1.3]
HV822_01565  long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
HV822_05975  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
HV822_06800  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
HV822_08000  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
HV822_09405  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
HV822_10250  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
HV822_10765  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
HV822_11010  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
HV822_16580  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
PMID:12061798
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
PMID:12518017
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
PMID:11337402
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
PMID:17573542
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
PMID:30201289
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
PMID:25203508
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
PMID:19686777
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
PMID:27553474
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
harr00020  Citrate cycle (TCA cycle)
harr00071  Fatty acid degradation
harr00410  beta-Alanine metabolism
harr00561  Glycerolipid metabolism
harr00564  Glycerophospholipid metabolism
harr00620  Pyruvate metabolism
harr00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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