KEGG   PATHWAY: hpse00630
Entry
hpse00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Hydrogenophaga pseudoflava
Class
Metabolism; Carbohydrate metabolism
Pathway map
hpse00630  Glyoxylate and dicarboxylate metabolism
hpse00630

Module
hpse_M00012  Glyoxylate cycle [PATH:hpse00630]
hpse_M00621  Glycine cleavage system [PATH:hpse00630]
Other DBs
GO: 0046487 0043648
Organism
Hydrogenophaga pseudoflava [GN:hpse]
Gene
HPF_14895  aceA; Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
HPF_15015  acsA5; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
HPF_13230  acsA4; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
HPF_21435  acsA6; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
HPF_07240  acsA2; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
HPF_21795  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
HPF_06950  mdh1; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
HPF_06915  gltA1; Citrate synthase [KO:K01647] [EC:2.3.3.1]
HPF_12640  citZ; Citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
HPF_07000  acoA; Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
HPF_06960  acnB; Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
HPF_06065  fadA2; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
HPF_08475  bktB; Beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
HPF_07965  thlA1; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
HPF_21130  thlA2; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
HPF_10755  fadA3; Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
HPF_14785  phbA2; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
HPF_12715  fadA4; Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
HPF_14780  phbB; Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
HPF_14730  accA6; Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K01965] [EC:6.4.1.3]
HPF_14735  accD1; putative propionyl-CoA carboxylase beta chain 5 [KO:K01966] [EC:6.4.1.3 2.1.3.15]
HPF_13085  accA5; Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
HPF_14745  scpA3; Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
HPF_02675  putative FAD-linked oxidoreductase [KO:K00104] [EC:1.1.99.14]
HPF_01105  putative FAD-linked oxidoreductase [KO:K11472] [EC:1.1.99.14]
HPF_01110  lutA; Lactate utilization protein A [KO:K11473] [EC:1.1.99.14]
HPF_21030  ghrA2; Glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
HPF_16645  ghrA1; Glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
HPF_08265  ghrB2; Glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
HPF_15935  hprA2; Glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
HPF_06210  gph1; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
HPF_18760  ppaX; Pyrophosphatase PpaX [KO:K01091] [EC:3.1.3.18]
HPF_21625  cbbZP; Phosphoglycolate phosphatase, plasmid [KO:K01091] [EC:3.1.3.18]
HPF_05955  cbbL; Ribulose bisphosphate carboxylase large chain [KO:K01601] [EC:4.1.1.39]
HPF_05960  cbbS1; Ribulose bisphosphate carboxylase small chain 1 [KO:K01602] [EC:4.1.1.39]
HPF_00595  puuA1; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
HPF_00635  glnT; Glutamine synthetase 3 [KO:K01915] [EC:6.3.1.2]
HPF_14825  glnA; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HPF_11960  puuA3; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
HPF_03880  puuA2; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
HPF_17155  3-hydroxylaminophenol mutase [KO:K01915] [EC:6.3.1.2]
HPF_16100  glyA2; Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
HPF_16555  gcvP; Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
HPF_16545  gcvT; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
HPF_10515  lpdA; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
HPF_10580  lpd; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
HPF_16550  gcvH; Glycine cleavage system H protein [KO:K02437]
HPF_05435  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
HPF_05440  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
HPF_05445  glxR2; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
HPF_09255  glxR3; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
HPF_15925  ttuD2; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
HPF_05450  ttuD1; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
HPF_09680  dmlA; D-malate dehydrogenase [decarboxylating] [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
HPF_08855  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
HPF_06780  fdhF1; Formate dehydrogenase H [KO:K00123] [EC:1.17.1.9]
HPF_17375  fdhF2; Formate dehydrogenase H [KO:K00123] [EC:1.17.1.9]
HPF_17380  nuoF2; NADH-quinone oxidoreductase subunit F [KO:K22515] [EC:1.17.1.9]
HPF_06785  fdhB1; Formate dehydrogenase iron-sulfur subunit [KO:K00124]
HPF_06795  fdoI; Formate dehydrogenase, cytochrome b556(fdo) subunit [KO:K00127]
HPF_09265  nlhH1; Carboxylesterase NlhH [KO:K01432] [EC:3.5.1.9]
HPF_07050  kynB3; Kynurenine formamidase [KO:K07130] [EC:3.5.1.9]
HPF_02690  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hpse00010  Glycolysis / Gluconeogenesis
hpse00020  Citrate cycle (TCA cycle)
hpse00030  Pentose phosphate pathway
hpse00053  Ascorbate and aldarate metabolism
hpse00071  Fatty acid degradation
hpse00230  Purine metabolism
hpse00250  Alanine, aspartate and glutamate metabolism
hpse00260  Glycine, serine and threonine metabolism
hpse00620  Pyruvate metabolism
hpse00710  Carbon fixation by Calvin cycle
hpse00750  Vitamin B6 metabolism
hpse00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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