KEGG   PATHWAY: hra00630
Entry
hra00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Haloplanus rallus
Class
Metabolism; Carbohydrate metabolism
Pathway map
hra00630  Glyoxylate and dicarboxylate metabolism
hra00630

Module
hra_M00621  Glycine cleavage system [PATH:hra00630]
hra_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hra00630]
Other DBs
GO: 0046487 0043648
Organism
Haloplanus rallus [GN:hra]
Gene
EI982_10700  isocitrate lyase/PEP mutase family protein [KO:K01637] [EC:4.1.3.1]
EI982_07505  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
EI982_04715  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
EI982_12130  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
EI982_09250  citrate synthase [KO:K01647] [EC:2.3.3.1]
EI982_10905  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
EI982_10955  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
EI982_12415  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
EI982_07250  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
EI982_06395  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
EI982_06405  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
EI982_01440  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
EI982_17400  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
EI982_01690  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
EI982_01685  acc operon protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
EI982_07225  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
EI982_01400  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
EI982_04860  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EI982_15180  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EI982_01405  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EI982_15575  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EI982_17730  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
EI982_06955  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
EI982_08020  glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
EI982_12650  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
EI982_13305  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
EI982_11970  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EI982_16550  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EI982_11960  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
EI982_11965  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
EI982_14385  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
EI982_16310  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
EI982_11975  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EI982_16315  gcvH; glycine cleavage system protein GcvH [KO:K02437]
EI982_18160  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
EI982_12985  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
EI982_02850  fuculose phosphate aldolase [KO:K01636] [EC:4.1.2.-]
EI982_09890  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
EI982_06800  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
EI982_06825  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hra00010  Glycolysis / Gluconeogenesis
hra00020  Citrate cycle (TCA cycle)
hra00030  Pentose phosphate pathway
hra00053  Ascorbate and aldarate metabolism
hra00071  Fatty acid degradation
hra00230  Purine metabolism
hra00250  Alanine, aspartate and glutamate metabolism
hra00260  Glycine, serine and threonine metabolism
hra00620  Pyruvate metabolism
hra00710  Carbon fixation by Calvin cycle
hra00750  Vitamin B6 metabolism
hra00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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