KEGG   PATHWAY: hrj04980
Entry
hrj04980                    Pathway                                
Name
Cobalamin transport and metabolism - Haliotis rubra (blacklip abalone)
Class
Organismal Systems; Digestive system
Pathway map
hrj04980  Cobalamin transport and metabolism
hrj04980

Organism
Haliotis rubra (blacklip abalone) [GN:hrj]
Gene
124254945  probable lysosomal cobalamin transporter [KO:K14617]
124272935  LOW QUALITY PROTEIN: probable lysosomal cobalamin transporter [KO:K14617]
124285399  lysosomal cobalamin transporter ABCD4-like [KO:K05678] [EC:7.6.2.8]
124285406  lysosomal cobalamin transporter ABCD4-like [KO:K05678] [EC:7.6.2.8]
124254934  cyanocobalamin reductase / alkylcobalamin dealkylase-like [KO:K14618] [EC:1.16.1.6 2.5.1.151]
124287957  LOW QUALITY PROTEIN: cobalamin trafficking protein CblD-like [KO:K26006]
124258682  corrinoid adenosyltransferase-like isoform X1 [KO:K00798] [EC:2.5.1.17]
124267740  LOW QUALITY PROTEIN: methylmalonic aciduria type A homolog, mitochondrial-like [KO:K07588] [EC:3.6.5.-]
124283386  LOW QUALITY PROTEIN: methylmalonyl-CoA mutase, mitochondrial-like [KO:K01847] [EC:5.4.99.2]
124281376  methionine synthase reductase-like [KO:K00597] [EC:1.16.1.8]
124273698  methionine synthase-like isoform X1 [KO:K00548] [EC:2.1.1.13]
124281774  zinc finger protein 143-like [KO:K20828]
124262318  host cell factor 1-like [KO:K14966]
124290557  peroxiredoxin-2-like isoform X1 [KO:K13279] [EC:1.11.1.24]
Compound
C00073  L-Methionine
C00091  Succinyl-CoA
C00101  Tetrahydrofolate
C00155  L-Homocysteine
C00194  Cobamide coenzyme
C00440  5-Methyltetrahydrofolate
C00541  Cob(II)alamin
C01213  (R)-Methylmalonyl-CoA
C02823  Cyanocobalamin
C06409  [Methionine synthase]-cob(II)alamin
C06410  [Methionine synthase]-methylcob(III)alamin
C06453  Methylcobalamin
C08230  Hydroxocobalamin
C22880  [Methionine synthase]-cob(I)alamin
Reference
PMID:35337617
  Authors
Nijland M, Martinez Felices JM, Slotboom DJ, Thangaratnarajah C
  Title
Membrane transport of cobalamin.
  Journal
Vitam Horm 119:121-148 (2022)
DOI:10.1016/bs.vh.2022.01.008
Reference
PMID:35337623
  Authors
Hannibal L, Jacobsen DW
  Title
Intracellular processing of vitamin B(12) by MMACHC (CblC).
  Journal
Vitam Horm 119:275-298 (2022)
DOI:10.1016/bs.vh.2022.02.001
Reference
PMID:35337626
  Authors
Watkins D, Rosenblatt DS
  Title
Inherited defects of cobalamin metabolism.
  Journal
Vitam Horm 119:355-376 (2022)
DOI:10.1016/bs.vh.2022.01.010
Reference
PMID:36422244
  Authors
Kosa M, Galla Z, Lenart I, Barath A, Grecso N, Racz G, Bereczki C, Monostori P
  Title
Vitamin B12 (Cobalamin): Its Fate from Ingestion to Metabolism with Particular Emphasis on Diagnostic Approaches of Acquired Neonatal/Infantile Deficiency  Detected by Newborn Screening.
  Journal
Metabolites 12:metabo12111104 (2022)
DOI:10.3390/metabo12111104
Reference
PMID:20301503
  Authors
Sloan JL, Carrillo N, Adams D, Venditti CP
  Title
Disorders of Intracellular Cobalamin Metabolism.
  Journal
GeneReviews(1993)
Reference
PMID:23539619
  Authors
Gherasim C, Lofgren M, Banerjee R
  Title
Navigating the B(12) road: assimilation, delivery, and disorders of cobalamin.
  Journal
J Biol Chem 288:13186-93 (2013)
DOI:10.1074/jbc.R113.458810
Related
pathway
hrj00270  Cysteine and methionine metabolism
hrj00280  Valine, leucine and isoleucine degradation
hrj00670  One carbon pool by folate
hrj04144  Endocytosis
KO pathway
ko04980   
LinkDB

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