KEGG   PATHWAY: kia00630
Entry
kia00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Roseateles sp. DAIF2
Class
Metabolism; Carbohydrate metabolism
Pathway map
kia00630  Glyoxylate and dicarboxylate metabolism
kia00630

Module
kia_M00012  Glyoxylate cycle [PATH:kia00630]
kia_M00621  Glycine cleavage system [PATH:kia00630]
kia_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:kia00630]
Other DBs
GO: 0046487 0043648
Organism
Roseateles sp. DAIF2 [GN:kia]
Gene
G8A07_14115  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
G8A07_08415  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
G8A07_10835  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
G8A07_25830  malate synthase G [KO:K01638] [EC:2.3.3.9]
G8A07_12880  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
G8A07_12915  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
G8A07_11060  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
G8A07_12855  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
G8A07_05375  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
G8A07_05675  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
G8A07_07935  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
G8A07_20100  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
G8A07_07940  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
G8A07_15035  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
G8A07_13145  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
G8A07_13135  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
G8A07_13790  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
G8A07_13120  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
G8A07_02590  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
G8A07_02585  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
G8A07_02580  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
G8A07_27060  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
G8A07_07760  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
G8A07_03705  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
G8A07_07385  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
G8A07_26180  HAD-IIIA family hydrolase [KO:K01091] [EC:3.1.3.18]
G8A07_17725  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
G8A07_16360  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
G8A07_02920  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
G8A07_13600  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
G8A07_15820  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
G8A07_15810  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
G8A07_03160  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
G8A07_07835  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
G8A07_19695  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
G8A07_15815  gcvH; glycine cleavage system protein GcvH [KO:K02437]
G8A07_07465  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
G8A07_01200  glycerate kinase [KO:K00865] [EC:2.7.1.165]
G8A07_07470  glycerate kinase [KO:K11529] [EC:2.7.1.165]
G8A07_04075  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
G8A07_13695  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
G8A07_18960  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
G8A07_18955  fdxH; formate dehydrogenase subunit beta [KO:K00124]
G8A07_18950  formate dehydrogenase subunit gamma [KO:K00127]
G8A07_17340  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
G8A07_17995  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
G8A07_08780  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
G8A07_20490  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
kia00010  Glycolysis / Gluconeogenesis
kia00020  Citrate cycle (TCA cycle)
kia00030  Pentose phosphate pathway
kia00053  Ascorbate and aldarate metabolism
kia00071  Fatty acid degradation
kia00230  Purine metabolism
kia00250  Alanine, aspartate and glutamate metabolism
kia00260  Glycine, serine and threonine metabolism
kia00620  Pyruvate metabolism
kia00710  Carbon fixation by Calvin cycle
kia00750  Vitamin B6 metabolism
kia00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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