KEGG   PATHWAY: kpnk00250
Entry
kpnk00250                   Pathway                                
Name
Alanine, aspartate and glutamate metabolism - Klebsiella pneumoniae Kp52.145
Class
Metabolism; Amino acid metabolism
Pathway map
kpnk00250  Alanine, aspartate and glutamate metabolism
kpnk00250

Other DBs
GO: 0006522 0006531 0006536
Organism
Klebsiella pneumoniae Kp52.145 [GN:kpnk]
Gene
BN49_1243  unnamed protein product; highly similar to putative aminotransferase class I and II from Pantoea sp (tr [KO:K00812] [EC:2.6.1.1]
BN49_2054  aspC; highly similar to aspartate aminotransferase from Escherichia coli strain K12 (sp [KO:K00813] [EC:2.6.1.1]
BN49_4108  nadB; highly similar to L-aspartate oxidase from Escherichia coli strain K12 (sp [KO:K00278] [EC:1.4.3.16]
BN49_2300  ansB; highly similar to L-asparaginase from Erwinia chrysanthemi (sp [KO:K01424] [EC:3.5.1.1]
BN49_2335  ansA; highly similar to putative L-asparaginase 1 from Escherichia coli O55:H7 strain CB9615 - EPEC (tr [KO:K01424] [EC:3.5.1.1]
BN49_1912  iaaA; highly similar to isoaspartyl dipeptidase with L-asparaginase activity from Escherichia coli O17:K52:H18 strain UMN026 - ExPEC (tr [KO:K13051] [EC:3.5.1.1 3.4.19.5]
BN49_5058  asnA; highly similar to asparagine synthetase A from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K01914] [EC:6.3.1.1]
BN49_1749  asnB; highly similar to asparagine synthetase B (glutamine-hydrolyzing) from Escherichia coli O6 (tr [KO:K01953] [EC:6.3.5.4]
BN49_1202  yafV; highly similar to UPF0012 hydrolase YafV from Escherichia coli strain K12 (sp [KO:K13566] [EC:3.5.1.3]
BN49_3898  unnamed protein product; highly similar to putative aminotransferase from Escherichia coli strain UTI89 - UPEC (tr [KO:K14260] [EC:2.6.1.66 2.6.1.2]
BN49_4903  aspA; highly similar to aspartate ammonia-lyase (Aspartase) from Escherichia coli strain UTI89 - UPEC (tr [KO:K01744] [EC:4.3.1.1]
BN49_0538  argG; highly similar to argininosuccinate synthase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K01940] [EC:6.3.4.5]
BN49_4607  arlY; highly similar to argininosuccinate lyase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K01755] [EC:4.3.2.1]
BN49_4856  purA; highly similar to putative adenylosuccinate synthetase PurA from Escherichia coli O111:H-strain 11128 - EHEC (tr [KO:K01939] [EC:6.3.4.4]
BN49_2228  purB; highly similar to adenylosuccinate lyase from Escherichia coli strain UTI89 - UPEC (tr [KO:K01756] [EC:4.3.2.2]
BN49_4780  pyrB; highly similar to aspartate carbamoyltransferase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00609] [EC:2.1.3.2]
BN49_4781  pyrI; highly similar to aspartate carbamoyltransferase regulatory chain from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00610]
BN49_0292  unnamed protein product; highly similar to 4-aminobutyrate aminotransferase from Escherichia coli strain K12 (sp [KO:K00823] [EC:2.6.1.19]
BN49_1223  gabT; highly similar to 4-aminobutyrate aminotransferase from Escherichia coli strain K12 (sp [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
BN49_1224  gabD; highly similar to succinate-semialdehyde dehydrogenase I, NADP-dependent from Escherichia coli O7:K1 strain IAI39 - ExPEC (tr [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BN49_2099  ssdH; similar to succinate-semialdehyde dehydrogenase (NAD(P)(+)) from Escherichia coli O139:H28 strain E24377A - ETEC (tr [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BN49_4420  unnamed protein product; highly similar to NAD-dependent aldehyde dehydrogenases from Enterobacter cloacae subsp. cloacae NCTC 9394 (tr [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BN49_2739  yneI; highly similar to aldehyde dehydrogenase-like protein YneI from Escherichia coli strain K12 (sp [KO:K08324] [EC:1.2.1.16 1.2.1.24]
BN49_0496  gltB; highly similar to glutamate synthase [NADPH] large chain from Escherichia coli strain K12 (sp [KO:K00265] [EC:1.4.1.13]
BN49_0495  gltD; highly similar to glutamate synthase subunit small from Escherichia coli B185 (tr [KO:K00266] [EC:1.4.1.13]
BN49_2554  unnamed protein product; highly similar to putative glutamic dehyrogenase-like protein from Salmonella typhimurium (tr [KO:K00261] [EC:1.4.1.3]
BN49_1237  unnamed protein product; highly similar to putative Glu-Leu-Phe-Val dehydrogenase from Pantoea sp. (tr [KO:K00261] [EC:1.4.1.3]
BN49_2344  gdhA; highly similar to NADP-specific glutamate dehydrogenase from Salmonella typhi (sp [KO:K00262] [EC:1.4.1.4]
BN49_2130  putA; highly similar to bifunctional protein PutA from Klebsiella aerogenes (sp [KO:K13821] [EC:1.5.5.2 1.2.1.88]
BN49_4684  glnA; highly similar to putative glutamine synthetase from Enterobacter gergoviae (tr [KO:K01915] [EC:6.3.1.2]
BN49_4299  carB; highly similar to carbamoyl-phosphate synthase large chain from Salmonella typhimurium (sp [KO:K01955] [EC:6.3.5.5]
BN49_4300  carA; highly similar to carbamoyl-phosphate synthase small chain from Escherichia coli strain SMS-3-5 - SECEC (tr [KO:K01956] [EC:6.3.5.5]
BN49_2740  glsA; highly similar to glutaminase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K01425] [EC:3.5.1.2]
BN49_5073  glmS; highly similar to glucosamine--fructose-6-phosphate aminotransferase from Escherichia coli O6 (sp [KO:K00820] [EC:2.6.1.16]
BN49_3919  purF; highly similar to amidophosphoribosyltransferase from Escherichia coli strain ATCC 33849 - DSM 4235 - NCIB 12045 - K12 - DH1 (tr [KO:K00764] [EC:2.4.2.14]
Compound
C00014  Ammonia
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00041  L-Alanine
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00122  Fumarate
C00152  L-Asparagine
C00158  Citrate
C00169  Carbamoyl phosphate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00352  D-Glucosamine 6-phosphate
C00402  D-Aspartate
C00438  N-Carbamoyl-L-aspartate
C00940  2-Oxoglutaramate
C01042  N-Acetyl-L-aspartate
C02362  2-Oxosuccinamate
C03090  5-Phosphoribosylamine
C03406  N-(L-Arginino)succinate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03912  (S)-1-Pyrroline-5-carboxylate
C12270  N-Acetylaspartylglutamate
C20775  beta-Citryl-L-glutamate
C20776  N-Acetylaspartylglutamylglutamate
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:9687539
  Authors
Wu G
  Title
Intestinal mucosal amino acid catabolism.
  Journal
J Nutr 128:1249-52 (1998)
DOI:10.1093/jn/128.8.1249
Related
pathway
kpnk00010  Glycolysis / Gluconeogenesis
kpnk00020  Citrate cycle (TCA cycle)
kpnk00220  Arginine biosynthesis
kpnk00230  Purine metabolism
kpnk00240  Pyrimidine metabolism
kpnk00260  Glycine, serine and threonine metabolism
kpnk00261  Monobactam biosynthesis
kpnk00300  Lysine biosynthesis
kpnk00330  Arginine and proline metabolism
kpnk00340  Histidine metabolism
kpnk00410  beta-Alanine metabolism
kpnk00460  Cyanoamino acid metabolism
kpnk00470  D-Amino acid metabolism
kpnk00480  Glutathione metabolism
kpnk00520  Amino sugar and nucleotide sugar metabolism
kpnk00620  Pyruvate metabolism
kpnk00630  Glyoxylate and dicarboxylate metabolism
kpnk00650  Butanoate metabolism
kpnk00660  C5-Branched dibasic acid metabolism
kpnk00760  Nicotinate and nicotinamide metabolism
kpnk00770  Pantothenate and CoA biosynthesis
kpnk00860  Porphyrin metabolism
kpnk00910  Nitrogen metabolism
KO pathway
ko00250   
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